| # | Title | Journal | Year | Citations |
|---|
| 1 | Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications | Biomaterials | 2005 | 5,951 |
| 2 | Genomic analyses identify molecular subtypes of pancreatic cancer | Nature | 2016 | 2,700 |
| 3 | Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial | Lancet Neurology, The | 2008 | 971 |
| 4 | Axonal pathology in traumatic brain injury | Experimental Neurology | 2013 | 949 |
| 5 | Diffuse axonal injury due to nonmissile head injury in humans: An analysis of 45 cases | Annals of Neurology | 1982 | 890 |
| 6 | Clinical Trials in Head Injury | Journal of Neurotrauma | 2002 | 868 |
| 7 | International multicenter pilot study of the first comprehensive self-completed nonmotor symptoms questionnaire for Parkinson's disease: The NMSQuest study | Movement Disorders | 2006 | 865 |
| 8 | The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: an unblinded randomised controlled trial | Lancet, The | 2007 | 850 |
| 9 | The metric properties of a novel non‐motor symptoms scale for Parkinson's disease: Results from an international pilot study | Movement Disorders | 2007 | 838 |
| 10 | Mutations in ATP2A2, encoding a Ca2+ pump, cause Darier disease | Nature Genetics | 1999 | 697 |
| 11 | Peripheral neuropathies and anti-glycolipid antibodies | Brain | 2002 | 679 |
| 12 | Glial‐Neuronal Interactions in Alzheimer's Disease: The Potential Role of a ‘Cytokine Cycle’ in Disease Progression | Brain Pathology | 1998 | 628 |
| 13 | Rapid sequence intubation in Scottish urban emergency departments | Emergency Medicine Journal | 2003 | 601 |
| 14 | Comprehensive analysis of the gene encoding filaggrin uncovers prevalent and rare mutations in ichthyosis vulgaris and atopic eczema | Nature Genetics | 2007 | 598 |
| 15 | Chronic neuropathologies of single and repetitive TBI: substrates of dementia? | Nature Reviews Neurology | 2013 | 590 |
| 16 | The BrainIT group: concept and core dataset definition | Acta Neurochirurgica | 2003 | 578 |
| 17 | Randomized controlled trial of intravenous immunoglobulin versus oral prednisolone in chronic inflammatory demyelinating polyradiculoneuropathy | Annals of Neurology | 2001 | 577 |
| 18 | Toxicity evaluation of replication-competent herpes simplex virus (ICP 34.5 null mutant 1716) in patients with recurrent malignant glioma | Gene Therapy | 2000 | 569 |
| 19 | β-Amyloid precursor protein (βAPP) as a marker for axonal injury after head injury | Neuroscience Letters | 1993 | 545 |
| 20 | Fatigue and basal ganglia | Journal of the Neurological Sciences | 2000 | 535 |
| 21 | Guidelines on the assessment of bleeding risk prior to surgery or invasive procedures | British Journal of Haematology | 2008 | 530 |
| 22 | The neurotropic herpes viruses: herpes simplex and varicella-zoster | Lancet Neurology, The | 2007 | 512 |
| 23 | Widespread Tau and Amyloid‐Beta Pathology Many Years After a Single Traumatic Brain Injury in Humans | Brain Pathology | 2012 | 507 |
| 24 | Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling | Nature Genetics | 2014 | 490 |
| 25 | Apolipoprotein E ε4 allele is associated with deposition of amyloid β-protein following head injury | Nature Medicine | 1995 | 488 |
| 26 | βA4 amyloid protein deposition in brain after head trauma | Lancet, The | 1991 | 476 |
| 27 | Tear Film Osmolarity: Determination of a Referent for Dry Eye Diagnosis | | 2006 | 467 |
| 28 | Prevalence of nonmotor symptoms in Parkinson's disease in an international setting; Study using nonmotor symptoms questionnaire in 545 patients | Movement Disorders | 2007 | 461 |
| 29 | Ischaemic brain damage in fatal non-missile head injuries | Journal of the Neurological Sciences | 1978 | 456 |
| 30 | Varicella zoster virus infection | Nature Reviews Disease Primers | 2015 | 435 |
| 31 | A review of screening tests for cognitive impairment | Journal of Neurology, Neurosurgery and Psychiatry | 2007 | 419 |
| 32 | Importance of the environment in meticillin-resistant Staphylococcus aureus acquisition: the case for hospital cleaning | Lancet Infectious Diseases, The | 2008 | 416 |
| 33 | Insomnia and health-related quality of life | Sleep Medicine Reviews | 2010 | 407 |
| 34 | Detection and characterization of MuSK antibodies in seronegative myasthenia gravis | Annals of Neurology | 2004 | 391 |
| 35 | The attention–intention–effort pathway in the development of psychophysiologic insomnia: A theoretical review | Sleep Medicine Reviews | 2006 | 391 |
| 36 | Association of interleukin-1 gene polymorphisms with Alzheimer's disease | Annals of Neurology | 2000 | 386 |
| 37 | Laparoscopic versus minilaparotomy cholecystectomy: a randomised trial | Lancet, The | 1994 | 385 |
| 38 | The fracture liaison service: success of a program for the evaluation and management of patients with osteoporotic fracture | Osteoporosis International | 2003 | 378 |
| 39 | Clinical features, diagnosis, and treatment of human African trypanosomiasis (sleeping sickness) | Lancet Neurology, The | 2013 | 360 |
| 40 | What can amnesic patients learn? | Neuropsychologia | 1976 | 351 |
| 41 | ASPECTS OF COMA AFTER SEVERE HEAD INJURY | Lancet, The | 1977 | 346 |
| 42 | The European Brain Injury Consortium Survey of Head Injuries | Acta Neurochirurgica | 1999 | 344 |
| 43 | Face processing impairments after encephalitis: amygdala damage and recognition of fear | Neuropsychologia | 1998 | 343 |
| 44 | The nondeclaration of nonmotor symptoms of Parkinson's disease to health care professionals: An international study using the nonmotor symptoms questionnaire | Movement Disorders | 2010 | 342 |
| 45 | Bone grafting, orthopaedic biomaterials, and the clinical need for bone engineering | Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine | 2010 | 341 |
| 46 | “Stepped Care”: A Health Technology Solution for Delivering Cognitive Behavioral Therapy as a First Line Insomnia Treatment | Sleep | 2009 | 340 |
| 47 | Depression: an inflammatory illness?: Figure 1 | Journal of Neurology, Neurosurgery and Psychiatry | 2012 | 339 |
| 48 | High sensitivity cardiac troponin and the under-diagnosis of myocardial infarction in women: prospective cohort study | BMJ, The | 2015 | 338 |
| 49 | Relationship between total body water and surface area in normal and obese subjects | Journal of Clinical Pathology | 1971 | 331 |
| 50 | Keratin 16 and keratin 17 mutations cause pachyonychia congenita | Nature Genetics | 1995 | 331 |
