| # | Title | Journal | Year | Citations |
|---|
| 1 | Clinical Practice Guideline for Screening and Management of High Blood Pressure in Children and Adolescents | Pediatrics | 2017 | 2,199 |
| 2 | Current concepts in the diagnosis and management of cytokine release syndrome | Blood | 2014 | 2,080 |
| 3 | Management of Postoperative Pain: A Clinical Practice Guideline From the American Pain Society, the American Society of Regional Anesthesia and Pain Medicine, and the American Society of Anesthesiologists' Committee on Regional Anesthesia, Executive Committee, and Administrative Council | Journal of Pain | 2016 | 2,040 |
| 4 | ASTCT Consensus Grading for Cytokine Release Syndrome and Neurologic Toxicity Associated with Immune Effector Cells | Biology of Blood and Marrow Transplantation | 2019 | 1,741 |
| 5 | Regression of Glioblastoma after Chimeric Antigen Receptor T-Cell Therapy | New England Journal of Medicine | 2016 | 1,326 |
| 6 | Prevalence of Type 1 and Type 2 Diabetes Among Children and Adolescents From 2001 to 2009 | JAMA - Journal of the American Medical Association | 2014 | 1,160 |
| 7 | A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing | Nature Neuroscience | 2012 | 1,153 |
| 8 | Comprehensive single-cell transcriptional profiling of a multicellular organism | Science | 2017 | 1,067 |
| 9 | A brain–computer interface using electrocorticographic signals in humans | Journal of Neural Engineering | 2004 | 1,066 |
| 10 | Guidelines for Family-Centered Care in the Neonatal, Pediatric, and Adult ICU | Critical Care Medicine | 2017 | 973 |
| 11 | Guidelines of care for the management of atopic dermatitis | Journal of the American Academy of Dermatology | 2014 | 970 |
| 12 | Pseudomonas aeruginosa and other predictors of mortality and morbidity in young children with cystic fibrosis | Pediatric Pulmonology | 2002 | 910 |
| 13 | Guidelines of care for the management of atopic dermatitis | Journal of the American Academy of Dermatology | 2014 | 889 |
| 14 | Huntington disease: natural history, biomarkers and prospects for therapeutics | Nature Reviews Neurology | 2014 | 873 |
| 15 | Intent-to-treat leukemia remission by CD19 CAR T cells of defined formulation and dose in children and young adults | Blood | 2017 | 861 |
| 16 | Intertumoral Heterogeneity within Medulloblastoma Subgroups | Cancer Cell | 2017 | 836 |
| 17 | International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data | Blood | 2022 | 814 |
| 18 | Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del mutation: a double-blind, randomised, phase 3 trial | Lancet, The | 2019 | 804 |
| 19 | Characteristics and Outcomes of Children With Coronavirus Disease 2019 (COVID-19) Infection Admitted to US and Canadian Pediatric Intensive Care Units | JAMA Pediatrics | 2020 | 785 |
| 20 | Kinetics and biomarkers of severe cytokine release syndrome after CD19 chimeric antigen receptor–modified T-cell therapy | Blood | 2017 | 774 |
| 21 | Diagnosis and management of Duchenne muscular dystrophy, part 1: diagnosis, and neuromuscular, rehabilitation, endocrine, and gastrointestinal and nutritional management | Lancet Neurology, The | 2018 | 767 |
| 22 | Guidelines of care for the management of atopic dermatitis | Journal of the American Academy of Dermatology | 2014 | 695 |
| 23 | KDIGO clinical practice guideline for the care of kidney transplant recipients: a summary | Kidney International | 2010 | 675 |
| 24 | Diagnosis and management of Duchenne muscular dystrophy, part 2: respiratory, cardiac, bone health, and orthopaedic management | Lancet Neurology, The | 2018 | 668 |
| 25 | Acquisition of a CD19-negative myeloid phenotype allows immune escape of MLL-rearranged B-ALL from CD19 CAR-T-cell therapy | Blood | 2016 | 622 |
| 26 | De novo germline and postzygotic mutations in AKT3, PIK3R2 and PIK3CA cause a spectrum of related megalencephaly syndromes | Nature Genetics | 2012 | 621 |
| 27 | Rhabdomyosarcoma | Nature Reviews Disease Primers | 2019 | 619 |
| 28 | Glial Lipid Droplets and ROS Induced by Mitochondrial Defects Promote Neurodegeneration | Cell | 2015 | 617 |
| 29 | Larotrectinib in patients with TRK fusion-positive solid tumours: a pooled analysis of three phase 1/2 clinical trials | Lancet Oncology, The | 2020 | 608 |
| 30 | In vitro generation of human pluripotent stem cell derived lung organoids | ELife | 2015 | 605 |
| 31 | Power-Law Scaling in the Brain Surface Electric Potential | PLoS Computational Biology | 2009 | 602 |
| 32 | The genomic landscape of hypodiploid acute lymphoblastic leukemia | Nature Genetics | 2013 | 588 |
| 33 | Exercise management in type 1 diabetes: a consensus statement | Lancet Diabetes and Endocrinology,the | 2017 | 588 |
| 34 | US Health Care Spending by Payer and Health Condition, 1996-2016 | JAMA - Journal of the American Medical Association | 2020 | 587 |
| 35 | Family-Centered Care: Current Applications and Future Directions in Pediatric Health Care | Maternal and Child Health Journal | 2012 | 577 |
| 36 | Breast Cancer Before Age 40 Years | Seminars in Oncology | 2009 | 574 |
| 37 | Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection | Science | 2014 | 573 |
| 38 | Bioactivity and Safety of IL13Rα2-Redirected Chimeric Antigen Receptor CD8+ T Cells in Patients with Recurrent Glioblastoma | Clinical Cancer Research | 2015 | 573 |
| 39 | Diagnosis of Cystic Fibrosis: Consensus Guidelines from the Cystic Fibrosis Foundation | Journal of Pediatrics | 2017 | 572 |
| 40 | Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children | Pediatric Critical Care Medicine | 2020 | 567 |
| 41 | PTEN Mutation Spectrum and Genotype-Phenotype Correlations in Bannayan-Riley-Ruvalcaba Syndrome Suggest a Single Entity With Cowden Syndrome | Human Molecular Genetics | 1999 | 562 |
| 42 | Modifiable Risk Factors and Major Cardiac Events Among Adult Survivors of Childhood Cancer | Journal of Clinical Oncology | 2013 | 558 |
| 43 | Molecular basis of renal fibrosis | Pediatric Nephrology | 2000 | 555 |
| 44 | Evaluation of the Patient Health Questionnaire-9 Item for Detecting Major Depression Among Adolescents | Pediatrics | 2010 | 551 |
| 45 | Fecal Microbiota Transplant for Treatment of Clostridium difficile Infection in Immunocompromised Patients | American Journal of Gastroenterology | 2014 | 546 |
| 46 | Global report on preterm birth and stillbirth (1 of 7): definitions, description of the burden and opportunities to improve data | BMC Pregnancy and Childbirth | 2010 | 538 |
| 47 | VX-445–Tezacaftor–Ivacaftor in Patients with Cystic Fibrosis and One or Two Phe508del Alleles | New England Journal of Medicine | 2018 | 509 |
| 48 | High Functional Diversity in Mycobacterium tuberculosis Driven by Genetic Drift and Human Demography | PLoS Biology | 2008 | 507 |
| 49 | Promoting coherent minimum reporting guidelines for biological and biomedical investigations: the MIBBI project | Nature Biotechnology | 2008 | 506 |
| 50 | Global and National Burden of Diseases and Injuries Among Children and Adolescents Between 1990 and 2013 | JAMA Pediatrics | 2016 | 479 |
