| # | Title | Journal | Year | Citations |
|---|
| 1 | Genomic analyses identify molecular subtypes of pancreatic cancer | Nature | 2016 | 2,700 |
| 2 | Global Surgery 2030: evidence and solutions for achieving health, welfare, and economic development | Lancet, The | 2015 | 2,466 |
| 3 | Genome-wide association study identifies novel breast cancer susceptibility loci | Nature | 2007 | 2,165 |
| 4 | Whole genomes redefine the mutational landscape of pancreatic cancer | Nature | 2015 | 2,132 |
| 5 | The global burden of low back pain: estimates from the Global Burden of Disease 2010 study | Annals of the Rheumatic Diseases | 2014 | 2,091 |
| 6 | The Quality in Australian Health Care Study | Medical Journal of Australia | 1995 | 2,072 |
| 7 | A systematic review of the global prevalence of low back pain | Arthritis and Rheumatism | 2012 | 2,007 |
| 8 | Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes | Nature | 2012 | 1,741 |
| 9 | Assessing risk of bias in prevalence studies: modification of an existing tool and evidence of interrater agreement | Journal of Clinical Epidemiology | 2012 | 1,721 |
| 10 | Posthepatectomy liver failure: A definition and grading by the International Study Group of Liver Surgery (ISGLS) | Surgery | 2011 | 1,703 |
| 11 | Mortality after all major types of osteoporotic fracture in men and women: an observational study | Lancet, The | 1999 | 1,684 |
| 12 | Cellular Actions of the Insulin-Like Growth Factor Binding Proteins | Endocrine Reviews | 2002 | 1,609 |
| 13 | Bile leakage after hepatobiliary and pancreatic surgery: A definition and grading of severity by the International Study Group of Liver Surgery | Surgery | 2011 | 1,596 |
| 14 | Cancer-related inflammation and treatment effectiveness | Lancet Oncology, The | 2014 | 1,525 |
| 15 | Ibrutinib versus Ofatumumab in Previously Treated Chronic Lymphoid Leukemia | New England Journal of Medicine | 2014 | 1,427 |
| 16 | 1999 World Health Organization-International Society of Hypertension Guidelines for the Management of Hypertension | Journal of Hypertension | 1999 | 1,232 |
| 17 | Influence of Age and Gender on the Pharmacokinetics and Pharmacodynamics of Remifentanil | Anesthesiology | 1997 | 1,201 |
| 18 | Epidemiology, Demographics, and Pathophysiology of Acute Spinal Cord Injury | Spine | 2001 | 1,132 |
| 19 | Drotrecogin Alfa (Activated) in Adults with Septic Shock | New England Journal of Medicine | 2012 | 1,112 |
| 20 | Prostate-specific membrane antigen PET-CT in patients with high-risk prostate cancer before curative-intent surgery or radiotherapy (proPSMA): a prospective, randomised, multicentre study | Lancet, The | 2020 | 1,108 |
| 21 | The systemic inflammation-based neutrophil–lymphocyte ratio: Experience in patients with cancer | Critical Reviews in Oncology/Hematology | 2013 | 1,106 |
| 22 | Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture | Nature Genetics | 2012 | 1,100 |
| 23 | Whole-genome landscapes of major melanoma subtypes | Nature | 2017 | 1,068 |
| 24 | Biological, clinical, and ethical advances of placebo effects | Lancet, The | 2010 | 1,055 |
| 25 | Multicenter, Randomized, Open-Label, Phase III Trial of Decitabine Versus Patient Choice, With Physician Advice, of Either Supportive Care or Low-Dose Cytarabine for the Treatment of Older Patients With Newly Diagnosed Acute Myeloid Leukemia | Journal of Clinical Oncology | 2012 | 998 |
| 26 | PD-1 Blockade with Cemiplimab in Advanced Cutaneous Squamous-Cell Carcinoma | New England Journal of Medicine | 2018 | 997 |
| 27 | A Comprehensive Review of the Placebo Effect: Recent Advances and Current Thought | Annual Review of Psychology | 2008 | 959 |
| 28 | Critical Care Services and 2009 H1N1 Influenza in Australia and New Zealand | New England Journal of Medicine | 2009 | 920 |
| 29 | Polypharmacy cutoff and outcomes: five or more medicines were used to identify community-dwelling older men at risk of different adverse outcomes | Journal of Clinical Epidemiology | 2012 | 891 |
| 30 | Chronic pain in Australia: a prevalence study | Pain | 2001 | 843 |
| 31 | ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro | Nature | 2005 | 826 |
| 32 | A longitudinal study of the prevalence and characteristics of pain in the first 5 years following spinal cord injury | Pain | 2003 | 810 |
| 33 | Short-Course Radiation plus Temozolomide in Elderly Patients with Glioblastoma | New England Journal of Medicine | 2017 | 810 |
| 34 | A Randomized, Controlled Trial of Early versus Late Initiation of Dialysis | New England Journal of Medicine | 2010 | 767 |
| 35 | 5th ESO-ESMO international consensus guidelines for advanced breast cancer (ABC 5) | Annals of Oncology | 2020 | 761 |
| 36 | The individual and socioeconomic impact of osteoarthritis | Nature Reviews Rheumatology | 2014 | 757 |
| 37 | Nonsteroidal Antiinflammatory Drugs — Differences and Similarities | New England Journal of Medicine | 1991 | 745 |
| 38 | Whole-genome landscape of pancreatic neuroendocrine tumours | Nature | 2017 | 716 |
| 39 | Respiratory rate: the neglected vital sign | Medical Journal of Australia | 2008 | 707 |
| 40 | Evolution of semi-quantitative whole joint assessment of knee OA: MOAKS (MRI Osteoarthritis Knee Score) | Osteoarthritis and Cartilage | 2011 | 690 |
| 41 | HRPT2, encoding parafibromin, is mutated in hyperparathyroidism–jaw tumor syndrome | Nature Genetics | 2002 | 686 |
| 42 | Venetoclax in relapsed or refractory chronic lymphocytic leukaemia with 17p deletion: a multicentre, open-label, phase 2 study | Lancet Oncology, The | 2016 | 676 |
| 43 | The IASP classification of chronic pain for ICD-11: chronic primary pain | Pain | 2019 | 645 |
| 44 | Safety and efficacy of imatinib cessation for CML patients with stable undetectable minimal residual disease: results from the TWISTER study | Blood | 2013 | 641 |
| 45 | The role of the CFP2C9-Leu 359 allelic variant in the tolbutamide polymorphism | Pharmacogenetics and Genomics | 1996 | 600 |
| 46 | Selective BRAF Inhibitors Induce Marked T-cell Infiltration into Human Metastatic Melanoma | Clinical Cancer Research | 2012 | 589 |
| 47 | Chemotherapy in Addition to Supportive Care Improves Survival in Advanced Non–Small-Cell Lung Cancer: A Systematic Review and Meta-Analysis of Individual Patient Data From 16 Randomized Controlled Trials | Journal of Clinical Oncology | 2008 | 582 |
| 48 | Results From a Pivotal, Open-Label, Phase II Study of Romidepsin in Relapsed or Refractory Peripheral T-Cell Lymphoma After Prior Systemic Therapy | Journal of Clinical Oncology | 2012 | 571 |
| 49 | The IASP classification of chronic pain for ICD-11: chronic neuropathic pain | Pain | 2019 | 571 |
| 50 | Clinical Presentation and Penetrance of Pheochromocytoma/Paraganglioma Syndromes | Journal of Clinical Endocrinology and Metabolism | 2006 | 560 |
