| Sporadic primary pulmonary hypertension is associated with germline mutations of the gene encoding BMPR-II, a receptor member of the TGF-beta family | Journal of Medical Genetics | 2000 | 503 |
| Low-dose transdermal testosterone therapy improves angina threshold in men with chronic stable angina: A randomized, double-blind, placebo-controlled study | Circulation | 2000 | 492 |
| A46R and A52R from vaccinia virus are antagonists of host IL-1 and toll-like receptor signaling | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 385 |
| BICALUTAMIDE MONOTHERAPY COMPARED WITH CASTRATION IN PATIENTS WITH NONMETASTATIC LOCALLY ADVANCED PROSTATE CANCER: 6.3 YEARS OF FOLLOWUP | Journal of Urology | 2000 | 274 |
| Men with coronary artery disease have lower levels of androgens than men with normal coronary angiograms | European Heart Journal | 2000 | 257 |
| Muscarinic receptor antagonists in the treatment of overactive bladder | Urology | 2000 | 236 |
| Arterial inflammation in mice lacking the interleukin 1 receptor antagonist gene | Journal of Experimental Medicine | 2000 | 232 |
| FLT3 internal tandem duplication mutations in adult acute myeloid leukaemia define a high-risk group | British Journal of Haematology | 2000 | 227 |
| Urothelium-derived inhibitory factor(s) influences on detrusor muscle contractility in vitro | British Journal of Pharmacology | 2000 | 218 |
| A comparison of egocentric and allocentric spatial memory in a patient with selective hippocampal damage | Neuropsychologia | 2000 | 216 |
| Cyclosporin for severe childhood atopic dermatitis: short course versus continuous therapy | British Journal of Dermatology | 2000 | 192 |
| Cytofluorometric methods for assessing absolute numbers of cell subsets in blood. European Working Group on Clinical Cell Analysis | Cytometry | 2000 | 179 |
| Relation between tissue structure and imposed electrical current flow in cervical neoplasia | Lancet, The | 2000 | 152 |
| Dexamethasone regulation of matrix metalloproteinase expression in CNS vascular endothelium | Brain | 2000 | 151 |
| A comparison of modified Howland circuits as current generators with current mirror type circuits | Physiological Measurement | 2000 | 147 |
| Peripheral nerve injuries associated with anaesthesia | Anaesthesia | 2000 | 127 |
| Chiral switches | Lancet, The | 2000 | 126 |
| The changing pattern of mortality and morbidity from radical cystectomy | BJU International | 2000 | 124 |
| Coronary and cardiovascular risk estimation for primary prevention: validation of a new Sheffield table in the 1995 Scottish health survey population | BMJ: British Medical Journal | 2000 | 118 |
| Guidelines on the diagnosis of noise-induced hearing loss for medicolegal purposes | Clinical Otolaryngology | 2000 | 118 |
| Dynamic shuttling of nuclear factor kappa B between the nucleus and cytoplasm as a consequence of inhibitor dissociation | Journal of Biological Chemistry | 2000 | 117 |
| Radiosurgery for epilepsy associated with cavernous malformation: retrospective study in 49 patients | Neurosurgery | 2000 | 95 |
| Bacterial meningitis in Malawian adults: pneumococcal disease is common, severe, and seasonal | Clinical Infectious Diseases | 2000 | 92 |
| Efficacy of trospium chloride in patients with detrusor instability: a placebo-controlled, randomized, double-blind, multicentre clinical trial | BJU International | 2000 | 81 |
| Characterisation of the human plunc gene, a gene product with an upper airways and nasopharyngeal restricted expression pattern | Biochimica Et Biophysica Acta Gene Regulatory Mechanisms | 2000 | 80 |
