| # | Title | Journal | Year | Citations |
|---|
| 1 | limma powers differential expression analyses for RNA-sequencing and microarray studies | Nucleic Acids Research | 2015 | 26,032 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 3 | Global, Regional, and National Burden of Cardiovascular Diseases for 10 Causes, 1990 to 2015 | Journal of the American College of Cardiology | 2017 | 2,705 |
| 4 | The global burden of group A streptococcal diseases | Lancet Infectious Diseases, The | 2005 | 2,384 |
| 5 | Genome-wide association study identifies novel breast cancer susceptibility loci | Nature | 2007 | 2,165 |
| 6 | Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics | PLoS Genetics | 2014 | 2,012 |
| 7 | DNA methylation-based classification of central nervous system tumours | Nature | 2018 | 1,872 |
| 8 | Nasal CPAP or Intubation at Birth for Very Preterm Infants | New England Journal of Medicine | 2008 | 1,704 |
| 9 | X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy | Nature Genetics | 2001 | 1,648 |
| 10 | Adolescence: a foundation for future health | Lancet, The | 2012 | 1,637 |
| 11 | Assessment and Development of Executive Function (EF) During Childhood | Child Neuropsychology | 2002 | 1,566 |
| 12 | Guideline to reference gene selection for quantitative real-time PCR | Biochemical and Biophysical Research Communications | 2004 | 1,409 |
| 13 | Antithrombotic Therapy in Neonates and Children | Chest | 2012 | 1,229 |
| 14 | Guidelines and definitions for research on epithelial–mesenchymal transition | Nature Reviews Molecular Cell Biology | 2020 | 1,195 |
| 15 | A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva | Nature Genetics | 2006 | 1,079 |
| 16 | Paracellin-1, a Renal Tight Junction Protein Required for Paracellular Mg2+ Resorption | Science | 1999 | 1,042 |
| 17 | Real-time PCR in virology | Nucleic Acids Research | 2002 | 1,041 |
| 18 | Interventions for preventing obesity in children | The Cochrane Library | 2019 | 1,041 |
| 19 | Mitochondrial diseases | Nature Reviews Disease Primers | 2016 | 1,001 |
| 20 | Worldwide trends in the prevalence of asthma symptoms: phase III of the International Study of Asthma and Allergies in Childhood (ISAAC) | Thorax | 2007 | 988 |
| 21 | PIM2: a revised version of the Paediatric Index of Mortality | Intensive Care Medicine | 2003 | 973 |
| 22 | Epithelial—mesenchymal and mesenchymal—epithelial transitions in carcinoma progression | Journal of Cellular Physiology | 2007 | 957 |
| 23 | Global patterns of mortality in young people: a systematic analysis of population health data | Lancet, The | 2009 | 935 |
| 24 | Programmed Anuclear Cell Death Delimits Platelet Life Span | Cell | 2007 | 910 |
| 25 | Early, Accurate Diagnosis and Early Intervention in Cerebral Palsy | JAMA Pediatrics | 2017 | 898 |
| 26 | International Pediatric Multiple Sclerosis Study Group criteria for pediatric multiple sclerosis and immune-mediated central nervous system demyelinating disorders: revisions to the 2007 definitions | Multiple Sclerosis Journal | 2013 | 883 |
| 27 | Neurodevelopmental outcome at 2 years of age after general anaesthesia and awake-regional anaesthesia in infancy (GAS): an international multicentre, randomised controlled trial | Lancet, The | 2016 | 865 |
| 28 | VIRUS PARTICLES IN EPITHELIAL CELLS OF DUODENAL MUCOSA FROM CHILDREN WITH ACUTE NON-BACTERIAL GASTROENTERITIS | Lancet, The | 1973 | 859 |
| 29 | Prevalence of challenge-proven IgE-mediated food allergy using population-based sampling and predetermined challenge criteria in infants | Journal of Allergy and Clinical Immunology | 2011 | 851 |
| 30 | Uniformity of rotavirus strain nomenclature proposed by the Rotavirus Classification Working Group (RCWG) | Archives of Virology | 2011 | 827 |
| 31 | ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro | Nature | 2005 | 826 |
| 32 | Risk-adapted craniospinal radiotherapy followed by high-dose chemotherapy and stem-cell rescue in children with newly diagnosed medulloblastoma (St Jude Medulloblastoma-96): long-term results from a prospective, multicentre trial | Lancet Oncology, The | 2006 | 811 |
| 33 | The reliability of three-dimensional kinematic gait measurements: A systematic review | Gait and Posture | 2009 | 808 |
| 34 | Mutations in smooth muscle α-actin (ACTA2) lead to thoracic aortic aneurysms and dissections | Nature Genetics | 2007 | 767 |
| 35 | Fathers' involvement and children's developmental outcomes: a systematic review of longitudinal studies | Acta Paediatrica, International Journal of Paediatrics | 2008 | 744 |
| 36 | Replication of Norovirus in Cell Culture Reveals a Tropism for Dendritic Cells and Macrophages | PLoS Biology | 2004 | 740 |
| 37 | The avian Z-linked gene DMRT1 is required for male sex determination in the chicken | Nature | 2009 | 728 |
| 38 | Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature | Nature Genetics | 2012 | 712 |
| 39 | Consensus Guidelines for the Diagnosis and Treatment of Growth Hormone (GH) Deficiency in Childhood and Adolescence: Summary Statement of the GH Research Society | Journal of Clinical Endocrinology and Metabolism | 2000 | 703 |
| 40 | Leigh syndrome: Clinical features and biochemical and DNA abnormalities | Annals of Neurology | 1996 | 694 |
| 41 | How much physical activity is enough to prevent unhealthy weight gain? Outcome of the IASO 1st Stock Conference and consensus statement | Obesity Reviews | 2003 | 694 |
| 42 | Immune Checkpoint Inhibition for Hypermutant Glioblastoma Multiforme Resulting From Germline Biallelic Mismatch Repair Deficiency | Journal of Clinical Oncology | 2016 | 692 |
| 43 | The Epidemiology of Childhood Cardiomyopathy in Australia | New England Journal of Medicine | 2003 | 650 |
| 44 | Generalized epilepsy with febrile seizures plus. A genetic disorder with heterogeneous clinical phenotypes | Brain | 1997 | 646 |
| 45 | Procreative Beneficence: Why We Should Select the Best Children | Bioethics | 2001 | 629 |
| 46 | Adolescent resilience: a concept analysis | Journal of Adolescence | 2003 | 629 |
| 47 | Does bullying cause emotional problems? A prospective study of young teenagers | BMJ: British Medical Journal | 2001 | 628 |
| 48 | Splatter: simulation of single-cell RNA sequencing data | Genome Biology | 2017 | 626 |
| 49 | A male-specific role for SOX9 in vertebrate sex determination | Development (Cambridge) | 1996 | 623 |
| 50 | Social and School Connectedness in Early Secondary School as Predictors of Late Teenage Substance Use, Mental Health, and Academic Outcomes | Journal of Adolescent Health | 2007 | 611 |
