| # | Title | Journal | Year | Citations |
|---|
| 1 | Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease | Nature | 2012 | 4,038 |
| 2 | Imatinib Compared with Interferon and Low-Dose Cytarabine for Newly Diagnosed Chronic-Phase Chronic Myeloid Leukemia | New England Journal of Medicine | 2003 | 3,227 |
| 3 | Five-Year Follow-up of Patients Receiving Imatinib for Chronic Myeloid Leukemia | New England Journal of Medicine | 2006 | 3,212 |
| 4 | Genomic analyses identify molecular subtypes of pancreatic cancer | Nature | 2016 | 2,700 |
| 5 | Whole genomes redefine the mutational landscape of pancreatic cancer | Nature | 2015 | 2,132 |
| 6 | The Quality in Australian Health Care Study | Medical Journal of Australia | 1995 | 2,072 |
| 7 | Hyperhomocysteinemia: An Independent Risk Factor for Vascular Disease | New England Journal of Medicine | 1991 | 2,023 |
| 8 | Rosuvastatin and Cardiovascular Events in Patients Undergoing Hemodialysis | New England Journal of Medicine | 2009 | 1,781 |
| 9 | Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes | Nature | 2012 | 1,741 |
| 10 | Functional Gastroduodenal Disorders | Gastroenterology | 2006 | 1,740 |
| 11 | What is polypharmacy? A systematic review of definitions | BMC Geriatrics | 2017 | 1,706 |
| 12 | Epidemiology of gastro-oesophageal reflux disease: a systematic review | Gut | 2005 | 1,522 |
| 13 | Nilotinib versus Imatinib for Newly Diagnosed Chronic Myeloid Leukemia | New England Journal of Medicine | 2010 | 1,497 |
| 14 | Update on the epidemiology of gastro-oesophageal reflux disease: a systematic review | Gut | 2014 | 1,444 |
| 15 | Plasma Homocysteine as a Risk Factor for Vascular Disease | JAMA - Journal of the American Medical Association | 1997 | 1,255 |
| 16 | Perspectives on cancer therapy-induced mucosal injury | Cancer | 2004 | 1,214 |
| 17 | Diagnosis and Treatment of Primary Adrenal Insufficiency: An Endocrine Society Clinical Practice Guideline | Journal of Clinical Endocrinology and Metabolism | 2016 | 1,166 |
| 18 | Prostate-specific membrane antigen PET-CT in patients with high-risk prostate cancer before curative-intent surgery or radiotherapy (proPSMA): a prospective, randomised, multicentre study | Lancet, The | 2020 | 1,108 |
| 19 | The effect on human tumor necrosis factor alpha and interleukin 1 beta production of diets enriched in n-3 fatty acids from vegetable oil or fish oil | American Journal of Clinical Nutrition | 1996 | 986 |
| 20 | Enzalutamide with Standard First-Line Therapy in Metastatic Prostate Cancer | New England Journal of Medicine | 2019 | 982 |
| 21 | Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial | Lancet Neurology, The | 2008 | 971 |
| 22 | The Development and Validation of an Endoscopic Grading System for Barrett’s Esophagus: The Prague C & M Criteria | Gastroenterology | 2006 | 931 |
| 23 | Dietary polyunsaturated fatty acids and inflammatory mediator production | American Journal of Clinical Nutrition | 2000 | 878 |
| 24 | Surgery alone versus chemoradiotherapy followed by surgery for resectable cancer of the oesophagus: a randomised controlled phase III trial | Lancet Oncology, The | 2005 | 876 |
| 25 | Cholesteryl Ester Transfer Protein | Arteriosclerosis, Thrombosis, and Vascular Biology | 2003 | 780 |
| 26 | The pathophysiology of primary dystonia | Brain | 1998 | 746 |
| 27 | Global Vascular Guidelines on the Management of Chronic Limb-Threatening Ischemia | European Journal of Vascular and Endovascular Surgery | 2019 | 741 |
| 28 | Combination nivolumab and ipilimumab or nivolumab alone in melanoma brain metastases: a multicentre randomised phase 2 study | Lancet Oncology, The | 2018 | 732 |
| 29 | Whole-genome landscape of pancreatic neuroendocrine tumours | Nature | 2017 | 716 |
| 30 | Respiratory rate: the neglected vital sign | Medical Journal of Australia | 2008 | 707 |
| 31 | 2015 Heart Rhythm Society Expert Consensus Statement on the Diagnosis and Treatment of Postural Tachycardia Syndrome, Inappropriate Sinus Tachycardia, and Vasovagal Syncope | Heart Rhythm | 2015 | 694 |
| 32 | Updated clinical practice guidelines for the prevention and treatment of mucositis | Cancer | 2007 | 692 |
| 33 | Clinical practice guidelines for the prevention and treatment of cancer therapy-induced oral and gastrointestinal mucositis | Cancer | 2004 | 691 |
| 34 | Pathophysiology of bradykinesia in Parkinson's disease | Brain | 2001 | 667 |
| 35 | Pulmonary-Vein Isolation for Atrial Fibrillation in Patients with Heart Failure | New England Journal of Medicine | 2008 | 654 |
| 36 | Effectiveness and Safety of Bronchial Thermoplasty in the Treatment of Severe Asthma | American Journal of Respiratory and Critical Care Medicine | 2010 | 650 |
| 37 | Sentinel Node Biopsy for Early-Stage Melanoma | Annals of Surgery | 2005 | 632 |
| 38 | Long‐term Outcomes of Catheter Ablation of Atrial Fibrillation: A Systematic Review and Meta‐analysis | Journal of the American Heart Association | 2013 | 622 |
| 39 | Physiotherapy for adult patients with critical illness: recommendations of the European Respiratory Society and European Society of Intensive Care Medicine Task Force on Physiotherapy for Critically Ill Patients | Intensive Care Medicine | 2008 | 567 |
| 40 | Immune Activation in Patients With Irritable Bowel Syndrome | Gastroenterology | 2007 | 561 |
| 41 | Nature and Frequency of Bisphosphonate-Associated Osteonecrosis of the Jaws in Australia | Journal of Oral and Maxillofacial Surgery | 2007 | 553 |
| 42 | Effect of Fecal Microbiota Transplantation on 8-Week Remission in Patients With Ulcerative Colitis | JAMA - Journal of the American Medical Association | 2019 | 548 |
| 43 | Long-term omeprazole treatment in resistant gastroesophageal reflux disease: Efficacy, safety, and influence on gastric mucosa | Gastroenterology | 2000 | 519 |
| 44 | Laparoscopic adjustable gastric banding in the treatment of obesity: A systematic literature review | Surgery | 2004 | 510 |
| 45 | Development of the GerdQ, a tool for the diagnosis and management of gastro‐oesophageal reflux disease in primary care | Alimentary Pharmacology and Therapeutics | 2009 | 497 |
| 46 | Hyperglycaemia slows gastric emptying in Type 1 (insulin-dependent) diabetes mellitus | Diabetologia | 1990 | 484 |
| 47 | Nilotinib versus imatinib for the treatment of patients with newly diagnosed chronic phase, Philadelphia chromosome-positive, chronic myeloid leukaemia: 24-month minimum follow-up of the phase 3 randomised ENESTnd trial | Lancet Oncology, The | 2011 | 444 |
| 48 | Long-term prognostic significance of early molecular response to imatinib in newly diagnosed chronic myeloid leukemia: an analysis from the International Randomized Study of Interferon and STI571 (IRIS) | Blood | 2010 | 440 |
| 49 | Outcomes of long-standing persistent atrial fibrillation ablation: A systematic review | Heart Rhythm | 2010 | 438 |
| 50 | Relationships of Upper Gastrointestinal Motor and Sensory Function With Glycemic Control | Diabetes Care | 2001 | 434 |
