| # | Title | Journal | Year | Citations |
|---|
| 1 | Photodynamic Therapy | Journal of the National Cancer Institute | 1998 | 4,721 |
| 2 | The Eighth Edition AJCC Cancer Staging Manual: Continuing to build a bridge from a population‐based to a more “personalized” approach to cancer staging | Ca-A Cancer Journal for Clinicians | 2017 | 3,940 |
| 3 | Non-Small Cell Lung Cancer: Epidemiology, Risk Factors, Treatment, and Survivorship | Mayo Clinic Proceedings | 2008 | 2,424 |
| 4 | A polymorphic DNA marker genetically linked to Huntington's disease | Nature | 1983 | 2,289 |
| 5 | Non-Small Cell Lung Cancer: Epidemiology, Risk Factors, Treatment, and Survivorship | Mayo Clinic Proceedings | 2008 | 1,906 |
| 6 | Surgical pathologic spread patterns of endometrial cancer: A gynecologic oncology group study | Cancer | 1987 | 1,720 |
| 7 | The single-step method of RNA isolation by acid guanidinium thiocyanate–phenol–chloroform extraction: twenty-something years on | Nature Protocols | 2006 | 1,642 |
| 8 | A graphic method for the determination and presentation of binding parameters in a complex system | Analytical Biochemistry | 1967 | 1,576 |
| 9 | A phase III trial of surgery with or without adjunctive external pelvic radiation therapy in intermediate risk endometrial adenocarcinoma: a Gynecologic Oncology Group study | Gynecologic Oncology | 2004 | 1,531 |
| 10 | The pathogenesis of cancer metastasis | Nature | 1980 | 1,472 |
| 11 | The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus | Nature | 1988 | 1,326 |
| 12 | Levels of selected carcinogens and toxicants in vapour from electronic cigarettes | Tobacco Control | 2014 | 1,324 |
| 13 | A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization | Cell | 1988 | 1,246 |
| 14 | Basic principles of photodynamic therapy | Journal of Porphyrins and Phthalocyanines | 2001 | 1,225 |
| 15 | Vitamin D signalling pathways in cancer: potential for anticancer therapeutics | Nature Reviews Cancer | 2007 | 1,215 |
| 16 | Association analysis identifies 65 new breast cancer risk loci | Nature | 2017 | 1,099 |
| 17 | Moderate expansion of a normally biallelic trinucleotide repeat in spinocerebellar ataxia type 2 | Nature Genetics | 1996 | 1,092 |
| 18 | Therapy of locally unresectable pancreatic carcinoma: A randomized comparison of high dose (6000 rads) radiation alone, moderate dose radiation (4000 rads + 5-fluorouracil), and high dose radiation + 5-fluorouracil. The gastrointestinal tumor study group | Cancer | 1981 | 1,025 |
| 19 | Lenalidomide after Stem-Cell Transplantation for Multiple Myeloma | New England Journal of Medicine | 2012 | 1,024 |
| 20 | Interleukin (IL) 15 is a novel cytokine that activates human natural killer cells via components of the IL-2 receptor. | Journal of Experimental Medicine | 1994 | 1,020 |
| 21 | A rule for termination-codon position within intron-containing genes: when nonsense affects RNA abundance | Trends in Biochemical Sciences | 1998 | 999 |
| 22 | Escape of Human Solid Tumors from T–Cell Recognition: Molecular Mechanisms and Functional Significance | Advances in Immunology | 1999 | 998 |
| 23 | Nibrin, a Novel DNA Double-Strand Break Repair Protein, Is Mutated in Nijmegen Breakage Syndrome | Cell | 1998 | 989 |
| 24 | The search for synergy: a critical review from a response surface perspective | Pharmacological Reviews | 1995 | 984 |
| 25 | Preparation of liposomes of defined size distribution by extrusion through polycarbonate membranes | Biochimica Et Biophysica Acta - Biomembranes | 1979 | 964 |
| 26 | A Comparison of Estimates of Michaelis-Menten Kinetic Constants from Various Linear Transformations | Journal of Biological Chemistry | 1965 | 941 |
| 27 | Sp1 and krüppel-like factor family of transcription factors in cell growth regulation and cancer | Journal of Cellular Physiology | 2001 | 925 |
| 28 | Separation of univalent fragments from the bivalent rabbit antibody molecule by reduction of disulfide bonds | Archives of Biochemistry and Biophysics | 1960 | 912 |
| 29 | Granulocytic sarcoma: A clinicopathologic study of 61 biopsied cases | Cancer | 1981 | 899 |
| 30 | The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma | Nature Genetics | 2014 | 871 |
| 31 | Preferred conformation and molecular packing of phosphatidylethanolamine and phosphatidylcholine | BBA - Biomembranes | 1981 | 865 |
| 32 | Dysferlin, a novel skeletal muscle gene, is mutated in Miyoshi myopathy and limb girdle muscular dystrophy | Nature Genetics | 1998 | 857 |
| 33 | Treatment of Patients With Low-Grade B-Cell Lymphoma With the Combination of Chimeric Anti-CD20 Monoclonal Antibody and CHOP Chemotherapy | Journal of Clinical Oncology | 1999 | 850 |
| 34 | Fever and the thermal regulation of immunity: the immune system feels the heat | Nature Reviews Immunology | 2015 | 795 |
| 35 | cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumour cell lines | Nature | 1986 | 778 |
| 36 | Rb1 and Trp53 cooperate to suppress prostate cancer lineage plasticity, metastasis, and antiandrogen resistance | Science | 2017 | 767 |
| 37 | Association between endometriosis and risk of histological subtypes of ovarian cancer: a pooled analysis of case–control studies | Lancet Oncology, The | 2012 | 753 |
| 38 | Cotransplantation of HLA-Identical Sibling Culture-Expanded Mesenchymal Stem Cells and Hematopoietic Stem Cells in Hematologic Malignancy Patients | Biology of Blood and Marrow Transplantation | 2005 | 745 |
| 39 | Tumor-infiltrating NY-ESO-1–specific CD8 + T cells are negatively regulated by LAG-3 and PD-1 in human ovarian cancer | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 744 |
| 40 | Oxidative damage to DNA in diabetes mellitus | Lancet, The | 1996 | 718 |
| 41 | An enhanced International Prognostic Index (NCCN-IPI) for patients with diffuse large B-cell lymphoma treated in the rituximab era | Blood | 2014 | 693 |
| 42 | Narrative communication in cancer prevention and control: A framework to guide research and application | Annals of Behavioral Medicine | 2007 | 683 |
| 43 | Potent activity of carfilzomib, a novel, irreversible inhibitor of the ubiquitin-proteasome pathway, against preclinical models of multiple myeloma | Blood | 2007 | 669 |
| 44 | Breast Cancer—Major changes in the American Joint Committee on Cancer eighth edition cancer staging manual | Ca-A Cancer Journal for Clinicians | 2017 | 649 |
| 45 | Metastatic non-small-cell lung cancer (NSCLC): ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up | Annals of Oncology | 2012 | 647 |
| 46 | (α-NaYbF4:Tm3+)/CaF2 Core/Shell Nanoparticles with Efficient Near-Infrared to Near-Infrared Upconversion for High-Contrast Deep Tissue Bioimaging | ACS Nano | 2012 | 647 |
| 47 | The molecular structure of lecithin dihydrate | Nature | 1979 | 643 |
| 48 | Aspergillosis | New England Journal of Medicine | 2009 | 640 |
| 49 | Management and survival of female breast cancer: Results of a national survey by the American college of surgeons | Cancer | 1980 | 637 |
| 50 | Haematogenous metastastic patterns in colonic carcinoma: An analysis of 1541 necropsies | Journal of Pathology | 1986 | 629 |
