| # | Title | Journal | Year | Citations |
|---|
| 1 | A Modified Poisson Regression Approach to Prospective Studies with Binary Data | American Journal of Epidemiology | 2004 | 6,963 |
| 2 | Estimating kinetic parameters from dynamic contrast-enhanced t1-weighted MRI of a diffusable tracer: Standardized quantities and symbols | Journal of Magnetic Resonance Imaging | 1999 | 2,856 |
| 3 | Dynamic functional connectivity: Promise, issues, and interpretations | NeuroImage | 2013 | 2,358 |
| 4 | Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel | European Heart Journal | 2017 | 2,292 |
| 5 | Vedolizumab as Induction and Maintenance Therapy for Ulcerative Colitis | New England Journal of Medicine | 2013 | 2,114 |
| 6 | Serious Infections and Mortality in Association With Therapies for Crohn’s Disease: TREAT Registry | Clinical Gastroenterology and Hepatology | 2006 | 831 |
| 7 | Imaging biomarker roadmap for cancer studies | Nature Reviews Clinical Oncology | 2017 | 792 |
| 8 | Low-density lipoproteins cause atherosclerotic cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus statement from the European Atherosclerosis Society Consensus Panel | European Heart Journal | 2020 | 776 |
| 9 | 2016 Canadian Cardiovascular Society Guidelines for the Management of Dyslipidemia for the Prevention of Cardiovascular Disease in the Adult | Canadian Journal of Cardiology | 2016 | 775 |
| 10 | Treatment of Ulcerative Colitis with a Humanized Antibody to the α4β7Integrin | New England Journal of Medicine | 2005 | 736 |
| 11 | The cellular inflammatory response in human spinal cords after injury | Brain | 2006 | 706 |
| 12 | 2012 Update of the Canadian Cardiovascular Society Guidelines for the Diagnosis and Treatment of Dyslipidemia for the Prevention of Cardiovascular Disease in the Adult | Canadian Journal of Cardiology | 2013 | 680 |
| 13 | Transient Notch Activation Initiates an Irreversible Switch from Neurogenesis to Gliogenesis by Neural Crest Stem Cells | Cell | 2000 | 674 |
| 14 | Resting-state networks show dynamic functional connectivity in awake humans and anesthetized macaques | Human Brain Mapping | 2013 | 667 |
| 15 | Differences between human and mouse embryonic stem cells | Developmental Biology | 2004 | 656 |
| 16 | 2009 Canadian Cardiovascular Society/Canadian guidelines for the diagnosis and treatment of dyslipidemia and prevention of cardiovascular disease in the adult – 2009 recommendations | Canadian Journal of Cardiology | 2009 | 653 |
| 17 | Serious Infection and Mortality in Patients With Crohn's Disease: More Than 5 Years of Follow-Up in the TREAT™ Registry | American Journal of Gastroenterology | 2012 | 652 |
| 18 | MRI Measures of Middle Cerebral Artery Diameter in Conscious Humans During Simulated Orthostasis | Stroke | 2000 | 642 |
| 19 | Rapid combinedT1 andT2 mapping using gradient recalled acquisition in the steady state | Magnetic Resonance in Medicine | 2003 | 642 |
| 20 | The safety of vedolizumab for ulcerative colitis and Crohn's disease | Gut | 2017 | 630 |
| 21 | Nuclear lamin A/C R482Q mutation in Canadian kindreds with Dunnigan-type familial partial lipodystrophy | Human Molecular Genetics | 2000 | 596 |
| 22 | Shift work and vascular events: systematic review and meta-analysis | BMJ, The | 2012 | 595 |
| 23 | Genomic alterations in cultured human embryonic stem cells | Nature Genetics | 2005 | 592 |
| 24 | Natalizumab for the Treatment of Active Crohn’s Disease: Results of the ENCORE Trial | Gastroenterology | 2007 | 586 |
| 25 | Bone marrow–derived stem cells initiate pancreatic regeneration | Nature Biotechnology | 2003 | 572 |
| 26 | Cytokines and BMP-4 promote hematopoietic differentiation of human embryonic stem cells | Blood | 2003 | 563 |
| 27 | Organization of visceral and limbic connections in the insular cortex of the rat | Journal of Comparative Neurology | 1991 | 483 |
| 28 | Evaluation of prostate segmentation algorithms for MRI: The PROMISE12 challenge | Medical Image Analysis | 2014 | 469 |
| 29 | C-Reactive Protein, Fecal Calprotectin, and Stool Lactoferrin for Detection of Endoscopic Activity in Symptomatic Inflammatory Bowel Disease Patients: A Systematic Review and Meta-Analysis | American Journal of Gastroenterology | 2015 | 465 |
| 30 | Developing an instrument to assess the endoscopic severity of ulcerative colitis: the Ulcerative Colitis Endoscopic Index of Severity (UCEIS) | Gut | 2012 | 463 |
| 31 | Motor Area Activity During Mental Rotation Studied by Time-Resolved Single-Trial fMRI | Journal of Cognitive Neuroscience | 2000 | 461 |
| 32 | A MOLECULAR PERSPECTIVE OF CTLA-4 FUNCTION | Annual Review of Immunology | 2006 | 459 |
| 33 | Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans | Nature | 2011 | 459 |
| 34 | Colectomy Rate Comparison After Treatment of Ulcerative Colitis With Placebo or Infliximab | Gastroenterology | 2009 | 440 |
| 35 | Characterization and culture of human embryonic stem cells | Nature Biotechnology | 2005 | 423 |
| 36 | Gleaning multicomponent T1 and T2 information from steady‐state imaging data | Magnetic Resonance in Medicine | 2008 | 413 |
| 37 | High-resolutionT1 andT2 mapping of the brain in a clinically acceptable time with DESPOT1 and DESPOT2 | Magnetic Resonance in Medicine | 2005 | 407 |
| 38 | Reliability and Initial Validation of the Ulcerative Colitis Endoscopic Index of Severity | Gastroenterology | 2013 | 354 |
| 39 | Endothelial and Hematopoietic Cell Fate of Human Embryonic Stem Cells Originates from Primitive Endothelium with Hemangioblastic Properties | Immunity | 2004 | 353 |
| 40 | Delayed Enhancement Magnetic Resonance Imaging Predicts Response to Cardiac Resynchronization Therapy in Patients With Intraventricular Dyssynchrony | Journal of the American College of Cardiology | 2006 | 348 |
| 41 | Poly(vinyl alcohol) cryogel phantoms for use in ultrasound and MR imaging | Physics in Medicine and Biology | 2004 | 346 |
| 42 | Electromagnetic Tracking in Medicine—A Review of Technology, Validation, and Applications | IEEE Transactions on Medical Imaging | 2014 | 344 |
| 43 | Effects of Adalimumab Therapy on Incidence of Hospitalization and Surgery in Crohn's Disease: Results From the CHARM Study | Gastroenterology | 2008 | 339 |
| 44 | Human Embryonic Stem Cells Possess Immune-Privileged Properties | Stem Cells | 2004 | 329 |
| 45 | Clinical Practice Guidelines for the Medical Management of Nonhospitalized Ulcerative Colitis: The Toronto Consensus | Gastroenterology | 2015 | 323 |
| 46 | Human fMRI evidence for the neural correlates of preparatory set | Nature Neuroscience | 2002 | 319 |
| 47 | Cerebrogenic Cardiac Arrhythmias | Archives of Neurology | 1990 | 315 |
| 48 | Use of Lipoprotein(a) in clinical practice: A biomarker whose time has come. A scientific statement from the National Lipid Association | Journal of Clinical Lipidology | 2019 | 315 |
| 49 | Acute rejection is associated with antibodies to non-Gal antigens in baboons using Gal-knockout pig kidneys | Nature Medicine | 2005 | 312 |
| 50 | TDP43 is a human low molecular weight neurofilament (hNFL) mRNA-binding protein | Molecular and Cellular Neurosciences | 2007 | 308 |
