| # | Title | Journal | Year | Citations |
|---|
| 1 | Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016 | Intensive Care Medicine | 2017 | 4,590 |
| 2 | Screening for Colorectal Cancer: U.S. Preventive Services Task Force Recommendation Statement | Annals of Internal Medicine | 2008 | 1,281 |
| 3 | Azithromycin for Prevention of Exacerbations of COPD | New England Journal of Medicine | 2011 | 1,057 |
| 4 | The Effect of Emergency Department Crowding on Clinically Oriented Outcomes | Academic Emergency Medicine | 2009 | 914 |
| 5 | Management of COVID-19 Respiratory Distress | JAMA - Journal of the American Medical Association | 2020 | 842 |
| 6 | Incidence of Hospitalized Rhabdomyolysis in Patients Treated With Lipid-Lowering Drugs | JAMA - Journal of the American Medical Association | 2004 | 768 |
| 7 | Use of Diagnostic Imaging Studies and Associated Radiation Exposure for Patients Enrolled in Large Integrated Health Care Systems, 1996-2010 | JAMA - Journal of the American Medical Association | 2012 | 685 |
| 8 | Effectiveness and Safety of Bronchial Thermoplasty in the Treatment of Severe Asthma | American Journal of Respiratory and Critical Care Medicine | 2010 | 650 |
| 9 | Prone positioning attenuates and redistributes ventilator-induced lung injury in dogs | Critical Care Medicine | 2000 | 608 |
| 10 | Effectiveness of Influenza Vaccine in the Community-Dwelling Elderly | New England Journal of Medicine | 2007 | 573 |
| 11 | American Burn Association Consensus Conference to Define Sepsis and Infection in Burns | Journal of Burn Care and Research | 2007 | 529 |
| 12 | Changes in the Prevalence of Hepatitis C Virus Infection, Nonalcoholic Steatohepatitis, and Alcoholic Liver Disease Among Patients With Cirrhosis or Liver Failure on the Waitlist for Liver Transplantation | Gastroenterology | 2017 | 487 |
| 13 | Intranasal Insulin Administration Dose-Dependently Modulates Verbal Memory and Plasma Amyloid-β in Memory-Impaired Older Adults | Journal of Alzheimer's Disease | 2008 | 477 |
| 14 | Towards clarification of the meaning of spirituality | Journal of Advanced Nursing | 2002 | 468 |
| 15 | Cognitive Therapy and Pharmacotherapy for Depression | Archives of General Psychiatry | 1992 | 441 |
| 16 | Severe premature coronary artery disease with protease inhibitors | Lancet, The | 1998 | 432 |
| 17 | Apixaban and dalteparin in active malignancy‐associated venous thromboembolism: The ADAM VTE trial | Journal of Thrombosis and Haemostasis | 2020 | 381 |
| 18 | The effects of baseline characteristics, glycaemia treatment approach, and glycated haemoglobin concentration on the risk of severe hypoglycaemia: post hoc epidemiological analysis of the ACCORD study | BMJ: British Medical Journal | 2010 | 359 |
| 19 | Validation of the Caprini Risk Assessment Model in Plastic and Reconstructive Surgery Patients | Journal of the American College of Surgeons | 2011 | 353 |
| 20 | How does cognitive therapy work? Cognitive change and symptom change in cognitive therapy and pharmacotherapy for depression. | Journal of Consulting and Clinical Psychology | 1990 | 322 |
| 21 | Risk Adjustment Using Automated Ambulatory Pharmacy Data | Medical Care | 2003 | 319 |
| 22 | Recombinant human nerve growth factor in the treatment of diabetic polyneuropathy | Neurology | 1998 | 294 |
| 23 | Bronchial thermoplasty: Long-term safety and effectiveness in patients with severe persistent asthma | Journal of Allergy and Clinical Immunology | 2013 | 288 |
| 24 | Biologic Rhythms in the Immune System | Chronobiology International | 1999 | 284 |
| 25 | Coronary Artery Disease in Patients With Out-of-Hospital Refractory Ventricular Fibrillation Cardiac Arrest | Journal of the American College of Cardiology | 2017 | 249 |
| 26 | Recruitment Maneuvers in Three Experimental Models of Acute Lung Injury | American Journal of Respiratory and Critical Care Medicine | 2000 | 244 |
| 27 | Standard cardiopulmonary resuscitation versus active compression-decompression cardiopulmonary resuscitation with augmentation of negative intrathoracic pressure for out-of-hospital cardiac arrest: a randomised trial | Lancet, The | 2011 | 240 |
| 28 | Mechanisms of mitochondrial dysfunction and energy deficiency in Alzheimer’s disease | Mitochondrion | 2007 | 239 |
| 29 | Treatment of Proximal Tibia Fractures Using the Less Invasive Stabilization System | Journal of Orthopaedic Trauma | 2004 | 238 |
| 30 | Biomechanical Evaluation of the Less Invasive Stabilization System, Angled Blade Plate, and Retrograde Intramedullary Nail for the Internal Fixation of Distal Femur Fractures | Journal of Orthopaedic Trauma | 2004 | 234 |
| 31 | Insurance Status and Access to Urgent Ambulatory Care Follow-up Appointments | JAMA - Journal of the American Medical Association | 2005 | 231 |
| 32 | Effect of blood transfusion on outcome after major burn injury: A multicenter study* | Critical Care Medicine | 2006 | 231 |
| 33 | ADHD Medications and Risk of Serious Cardiovascular Events in Young and Middle-aged Adults | JAMA - Journal of the American Medical Association | 2011 | 231 |
| 34 | Validity of diabetes self-reports in the Women's Health Initiative: comparison with medication inventories and fasting glucose measurements | Clinical Trials | 2008 | 229 |
| 35 | Relationship Between Modifiable Health Risks and Short-term Health Care Charges | JAMA - Journal of the American Medical Association | 1999 | 221 |
| 36 | Diaphragm ultrasound as indicator of respiratory effort in critically ill patients undergoing assisted mechanical ventilation: a pilot clinical study | Critical Care | 2015 | 219 |
| 37 | Intranasal administration of insulin-like growth factor-I bypasses the blood–brain barrier and protects against focal cerebral ischemic damage | Journal of the Neurological Sciences | 2001 | 216 |
| 38 | Twitter as a tool for communication and knowledge exchange in academic medicine: A guide for skeptics and novices | Medical Teacher | 2015 | 214 |
| 39 | Intranasal administration of interferon beta bypasses the blood–brain barrier to target the central nervous system and cervical lymph nodes: a non-invasive treatment strategy for multiple sclerosis | Journal of Neuroimmunology | 2004 | 211 |
| 40 | Synthetic Cannabinoid Intoxication: A Case Series and Review | Journal of Emergency Medicine | 2013 | 210 |
| 41 | Improved Survival With Extracorporeal Cardiopulmonary Resuscitation Despite Progressive Metabolic Derangement Associated With Prolonged Resuscitation | Circulation | 2020 | 204 |
| 42 | Inhalation injury: epidemiology, pathology, treatment strategies | Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine | 2013 | 198 |
| 43 | Outcomes in Patients with Vasodilatory Shock and Renal Replacement Therapy Treated with Intravenous Angiotensin II | Critical Care Medicine | 2018 | 186 |
| 44 | Proximal Junctional Kyphosis in Primary Adult Deformity Surgery | Neurosurgery | 2013 | 184 |
| 45 | Emergency department crowding | Annals of Emergency Medicine | 2003 | 183 |
| 46 | A Comparison of Internet and Print-Based Physical Activity Interventions | Archives of Internal Medicine | 2007 | 183 |
| 47 | High-dose insulin therapy in beta-blocker and calcium channel-blocker poisoning | Clinical Toxicology | 2011 | 183 |
| 48 | Mindfulness-Based Stress Reduction for Family Caregivers: A Randomized Controlled Trial | Gerontologist, The | 2013 | 183 |
| 49 | Ventilatory management of acute respiratory distress syndrome: A consensus of two | Critical Care Medicine | 2004 | 179 |
| 50 | Diabetes, Metformin, and Breast Cancer in Postmenopausal Women | Journal of Clinical Oncology | 2012 | 179 |
