| # | Title | Journal | Year | Citations |
|---|
| 1 | Phosphoinositide 3-Kinase δ Gene Mutation Predisposes to Respiratory Infection and Airway Damage | Science | 2013 | 541 |
| 2 | Estimated Life Expectancy in a Scottish Cohort With Type 1 Diabetes, 2008-2010 | JAMA - Journal of the American Medical Association | 2015 | 454 |
| 3 | Surgical treatment of incisional hernia | British Journal of Surgery | 2002 | 424 |
| 4 | Clinical spectrum and features of activated phosphoinositide 3-kinase δ syndrome: A large patient cohort study | Journal of Allergy and Clinical Immunology | 2017 | 377 |
| 5 | Incidence and phenotypes of childhood-onset genetic epilepsies: a prospective population-based national cohort | Brain | 2019 | 248 |
| 6 | Drug-disease and drug-drug interactions: systematic examination of recommendations in 12 UK national clinical guidelines | BMJ, The | 2015 | 247 |
| 7 | Primary Cutaneous B-Cell Lymphoma and Borrelia burgdorferi Infection in Patients From the Highlands of Scotland | American Journal of Surgical Pathology | 2000 | 236 |
| 8 | Mortality in Parkinson's disease: A systematic review and meta‐analysis | Movement Disorders | 2014 | 229 |
| 9 | British Society of Gastroenterology/Association of Coloproctology of Great Britain and Ireland/Public Health England post-polypectomy and post-colorectal cancer resection surveillance guidelines | Gut | 2020 | 228 |
| 10 | Incidence of and survival from malignant melanoma in Scotland: an epidemiological study | Lancet, The | 2002 | 195 |
| 11 | Evaluation of enteropathy-associated T-cell lymphoma comparing standard therapies with a novel regimen including autologous stem cell transplantation | Blood | 2010 | 194 |
| 12 | Matrix metalloproteinases in acute lung injury: mediators of injury and drivers of repair | European Respiratory Journal | 2011 | 187 |
| 13 | Stapled versus handsewn methods for ileocolic anastomoses | The Cochrane Library | 2011 | 174 |
| 14 | Haemorrhoidal artery ligation versus rubber band ligation for the management of symptomatic second-degree and third-degree haemorrhoids (HubBLe): a multicentre, open-label, randomised controlled trial | Lancet, The | 2016 | 168 |
| 15 | Early mortality after surgical fixation of hip fractures in the elderly | Journal of Bone and Joint Surgery: British Volume | 2008 | 164 |
| 16 | Cutaneous malignant melanoma, Scotland, 1979-89 | Lancet, The | 1992 | 157 |
| 17 | Comparison of stapled haemorrhoidopexy with traditional excisional surgery for haemorrhoidal disease (eTHoS): a pragmatic, multicentre, randomised controlled trial | Lancet, The | 2016 | 147 |
| 18 | Reduction of low- and high-grade cervical abnormalities associated with high uptake of the HPV bivalent vaccine in Scotland | British Journal of Cancer | 2014 | 146 |
| 19 | Estrogen and androgen signaling in the pathogenesis of BPH | Nature Reviews Urology | 2011 | 144 |
| 20 | Central Corneal Thickness Is Highly Heritable: The Twin Eye Studies | Nature Reviews Urology | 2005 | 133 |
| 21 | Bioactive polyphenols and cardiovascular disease: chemical antagonists, pharmacological agents or xenobiotics that drive an adaptive response? | British Journal of Pharmacology | 2017 | 117 |
| 22 | The use of intravenous lidocaine for postoperative pain and recovery: international consensus statement on efficacy and safety | Anaesthesia | 2021 | 116 |
| 23 | Primary Cutaneous Follicular Lymphoma | American Journal of Surgical Pathology | 2002 | 109 |
| 24 | Surgical techniques for the treatment of nasal valve collapse | Laryngoscope | 2009 | 107 |
| 25 | Metastatic Crohn's disease | British Journal of Dermatology | 1976 | 106 |
| 26 | To test or not to test? Laboratory support for the diagnosis of Lyme borreliosis: a position paper of ESGBOR, the ESCMID study group for Lyme borreliosis | Clinical Microbiology and Infection | 2018 | 103 |
| 27 | Simultaneous Diagnosis of Toxoplasmosis in Goats and Goatowner's Family | Scandinavian Journal of Infectious Diseases | 1990 | 102 |
| 28 | EuroEco (European Health Economic Trial on Home Monitoring in ICD Patients): a provider perspective in five European countries on costs and net financial impact of follow-up with or without remote monitoring | European Heart Journal | 2015 | 102 |
| 29 | Primary Cutaneous Diffuse Large B-cell Lymphoma | American Journal of Surgical Pathology | 2003 | 95 |
| 30 | Evolution of cardiorespiratory interactions with age | Philosophical Transactions Series A, Mathematical, Physical, and Engineering Sciences | 2013 | 95 |
| 31 | Tumour necrosis factor inhibition versus rituximab for patients with rheumatoid arthritis who require biological treatment (ORBIT): an open-label, randomised controlled, non-inferiority, trial | Lancet, The | 2016 | 95 |
| 32 | European Society of ColoProctology: guideline for haemorrhoidal disease | Colorectal Disease | 2020 | 95 |
| 33 | Melanoma incidence and mortality in Scotland 1979–2003 | British Journal of Cancer | 2007 | 94 |
| 34 | Neurological sequelae in children after prolonged propofol infusion | Anaesthesia | 1992 | 92 |
| 35 | Combination therapy with sulfasalazine and methotrexate is more effective than either drug alone in patients with rheumatoid arthritis with a suboptimal response to sulfasalazine: results from the double-blind placebo-controlled MASCOT study | Annals of the Rheumatic Diseases | 2006 | 92 |
| 36 | Mercaptopurine versus placebo to prevent recurrence of Crohn's disease after surgical resection (TOPPIC): a multicentre, double-blind, randomised controlled trial | The Lancet Gastroenterology and Hepatology | 2016 | 91 |
| 37 | Factors influencing time from presentation to treatment of colorectal and breast cancer in urban and rural areas | British Journal of Cancer | 2004 | 90 |
| 38 | Borrelia burgdorferi -associated cutaneous marginal zone lymphoma: a clinicopathological study of two cases illustrating the temporal progression of B. burgdorferi -associated B-cell proliferation in the skin | Histopathology | 2000 | 88 |
| 39 | Real-time ultrasound diagnosis of deep vein thrombosis: A comparison with venography | Clinical Radiology | 1987 | 86 |
| 40 | The efficacy and tolerance of mifepristone and prostaglandin in termination of pregnancy of less than 63 days gestation; UK multicentre study—Final results | Contraception | 1997 | 86 |
| 41 | Population-based cohort study of outcomes following cholecystectomy for benign gallbladder diseases | British Journal of Surgery | 2016 | 84 |
| 42 | Microdeletion in a FAAH pseudogene identified in a patient with high anandamide concentrations and pain insensitivity | British Journal of Anaesthesia | 2019 | 82 |
| 43 | Impact of postoperative non-steroidal anti-inflammatory drugs on adverse events after gastrointestinal surgery | British Journal of Surgery | 2014 | 81 |
| 44 | Digital Technology Interventions for Risk Factor Modification in Patients With Cardiovascular Disease: Systematic Review and Meta-analysis | JMIR MHealth and UHealth | 2021 | 81 |
| 45 | Does an ileoanal pouch offer a better quality of life than a permanent ileostomy for patients with ulcerative colitis? | Journal of Gastrointestinal Surgery | 2003 | 80 |
| 46 | Louping ill in man: A forgotten disease | Journal of Infection | 1991 | 79 |
| 47 | Whole-leg duplex mapping for varicose veins: Observations on patterns of reflux in recurrent and primary legs, with clinical correlation | European Journal of Vascular and Endovascular Surgery | 2003 | 79 |
| 48 | N-Glycan Profile and Kidney Disease in Type 1 Diabetes | Diabetes Care | 2018 | 75 |
| 49 | Congenital toxoplasmosis: A prospective survey in the West of Scotland | Journal of Infection | 1981 | 74 |
| 50 | Activation of nuclear factor kappa B in Crohn's disease | Inflammation Research | 1998 | 73 |
