| # | Title | Journal | Year | Citations |
|---|
| 1 | Molecular Beacons: Probes that Fluoresce upon Hybridization | Nature Biotechnology | 1996 | 3,956 |
| 2 | Stochastic mRNA Synthesis in Mammalian Cells | PLoS Biology | 2006 | 1,528 |
| 3 | Multicolor molecular beacons for allele discrimination | Nature Biotechnology | 1998 | 1,276 |
| 4 | Structural Mechanism for Rifampicin Inhibition of Bacterial RNA Polymerase | Cell | 2001 | 1,219 |
| 5 | Proposal for Standardization of Optimized Mycobacterial Interspersed Repetitive Unit-Variable-Number Tandem Repeat Typing of Mycobacterium tuberculosis | Journal of Clinical Microbiology | 2006 | 1,181 |
| 6 | A small-molecule nitroimidazopyran drug candidate for the treatment of tuberculosis | Nature | 2000 | 971 |
| 7 | Mycobacterium tuberculosis Pathogenesis and Molecular Determinants of Virulence | Clinical Microbiology Reviews | 2003 | 925 |
| 8 | Synthesis of staphylococcal virulence factors is controlled by a regulatory RNA molecule. | EMBO Journal | 1993 | 898 |
| 9 | Evaluation of Protein A Gene Polymorphic Region DNA Sequencing for Typing of Staphylococcus aureus Strains | Journal of Clinical Microbiology | 1999 | 898 |
| 10 | Combination of Multiplex PCRs for Staphylococcal Cassette Chromosome mec Type Assignment: Rapid Identification System for mec , ccr , and MajorDifferences in Junkyard Regions | Antimicrobial Agents and Chemotherapy | 2007 | 886 |
| 11 | Recognition of haemagglutinins on virus-infected cells by NKp46 activates lysis by human NK cells | Nature | 2001 | 844 |
| 12 | A third recognition element in bacterial promoters: DNA binding by the alpha subunit of RNA polymerase | Science | 1993 | 745 |
| 13 | MicroRNA Let-7a Down-regulates MYC and Reverts MYC-Induced Growth in Burkitt Lymphoma Cells | Cancer Research | 2007 | 711 |
| 14 | DNA uptake during bacterial transformation | Nature Reviews Microbiology | 2004 | 689 |
| 15 | DNA gyrase, topoisomerase IV, and the 4-quinolones | Microbiology and Molecular Biology Reviews | 1997 | 687 |
| 16 | Toward the structural genomics of complexes: Crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 683 |
| 17 | A glycolipid of hypervirulent tuberculosis strains that inhibits the innate immune response | Nature | 2004 | 673 |
| 18 | The global problem of antifungal resistance: prevalence, mechanisms, and management | Lancet Infectious Diseases, The | 2017 | 670 |
| 19 | Bistability in bacteria | Molecular Microbiology | 2006 | 624 |
| 20 | Efficiencies of fluorescence resonance energy transfer and contact-mediated quenching in oligonucleotide probes | Nucleic Acids Research | 2002 | 568 |
| 21 | DNA Uptake in Bacteria | Annual Review of Microbiology | 1999 | 553 |
| 22 | Requirement for MAP kinase (ERK2) activity in interferon alpha- and interferon beta-stimulated gene expression through STAT proteins | Science | 1995 | 548 |
| 23 | Cloning, characterization, and sequencing of an accessory gene regulator (agr) in Staphylococcus aureus | Journal of Bacteriology | 1988 | 535 |
| 24 | Synthesis of staphylococcal virulence factors is controlled by a regulatory RNA molecule | EMBO Journal | 1993 | 507 |
| 25 | Cleavage of Nucleic Acids by Bleomycin | Chemical Reviews | 1998 | 463 |
| 26 | Global dissemination of the Mycobacterium tuberculosis W-Beijing family strains | Trends in Microbiology | 2002 | 452 |
| 27 | Resistance to echinocandin-class antifungal drugs | Drug Resistance Updates | 2007 | 440 |
| 28 | spa Typing Method for Discriminating among Staphylococcus aureus Isolates: Implications for Use of a Single Marker To Detect Genetic Micro- and Macrovariation | Journal of Clinical Microbiology | 2004 | 437 |
| 29 | Evidence for a clonal origin of methicillin resistance in Staphylococcus aureus | Science | 1993 | 423 |
| 30 | The RNA–DNA Hybrid Maintains the Register of Transcription by Preventing Backtracking of RNA Polymerase | Cell | 1997 | 423 |
| 31 | Visualizing the distribution and transport of mRNAs in living cells | Proceedings of the National Academy of Sciences of the United States of America | 2003 | 408 |
| 32 | Molecular beacon sequence analysis for detecting drug resistance in Mycobacterium tuberculosis | Nature Biotechnology | 1998 | 393 |
| 33 | A Structural Model of Transcription Elongation | Science | 2000 | 381 |
| 34 | Specific Substitutions in the Echinocandin Target Fks1p Account for Reduced Susceptibility of Rare Laboratory and Clinical Candida sp. Isolates | Antimicrobial Agents and Chemotherapy | 2005 | 380 |
| 35 | A multicentre study of antifungal susceptibility patterns among 350 Candida auris isolates (2009–17) in India: role of the ERG11 and FKS1 genes in azole and echinocandin resistance | Journal of Antimicrobial Chemotherapy | 2018 | 380 |
| 36 | Transcript cleavage factors from E. coli | Cell | 1993 | 360 |
| 37 | The mutant selection window and antimicrobial resistance | Journal of Antimicrobial Chemotherapy | 2003 | 355 |
| 38 | Control of bacterial DNA supercoiling | Molecular Microbiology | 1992 | 352 |
| 39 | The Ins and Outs of DNA Transfer in Bacteria | Science | 2005 | 351 |
| 40 | Differential expression of 10 sigma factor genes in Mycobacterium tuberculosis | Molecular Microbiology | 1999 | 348 |
| 41 | C. elegans ORFeome version 1.1: experimental verification of the genome annotation and resource for proteome-scale protein expression | Nature Genetics | 2003 | 347 |
| 42 | Restricting the Selection of Antibiotic‐Resistant Mutants: A General Strategy Derived from Fluoroquinolone Studies | Clinical Infectious Diseases | 2001 | 346 |
| 43 | Emergence of vancomycin-resistant enterococci in New York City | Lancet, The | 1993 | 345 |
| 44 | Mutant Selection Window Hypothesis Updated | Clinical Infectious Diseases | 2007 | 345 |
| 45 | Staphylococcal Plasmids and their Replication | Annual Review of Microbiology | 1989 | 344 |
| 46 | Transcriptional arrest: Escherichia coli RNA polymerase translocates backward, leaving the 3' end of the RNA intact and extruded | Proceedings of the National Academy of Sciences of the United States of America | 1997 | 340 |
| 47 | Epidemic community-associated methicillin-resistant Staphylococcus aureus : Recent clonal expansion and diversification | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 340 |
| 48 | Culture-independent discovery of the malacidins as calcium-dependent antibiotics with activity against multidrug-resistant Gram-positive pathogens | Nature Microbiology | 2018 | 338 |
| 49 | Molecular Epidemiology of Tuberculosis: Current Insights | Clinical Microbiology Reviews | 2006 | 325 |
| 50 | Tyrosine phosphorylated p91 binds to a single element in the ISGF2/IRF-1 promoter to mediate induction by IFN alpha and IFN gamma, and is likely to autoregulate the p91 gene. | EMBO Journal | 1994 | 321 |
