| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Synaptic density in human frontal cortex — Developmental changes and effects of aging | Brain Research | 1979 | 2,345 |
| 3 | A Study of Sexuality and Health among Older Adults in the United States | New England Journal of Medicine | 2007 | 1,783 |
| 4 | Treatment of Stage I and II Non-small Cell Lung Cancer | Chest | 2013 | 1,117 |
| 5 | Febuxostat Compared with Allopurinol in Patients with Hyperuricemia and Gout | New England Journal of Medicine | 2005 | 1,098 |
| 6 | A developmental approach to complex PTSD: Childhood and adult cumulative trauma as predictors of symptom complexity | Journal of Traumatic Stress | 2009 | 1,053 |
| 7 | Cardiac interstitium in health and disease: The fibrillar collagen network | Journal of the American College of Cardiology | 1989 | 983 |
| 8 | Results of Conservative Management of Clinically Localized Prostate Cancer | New England Journal of Medicine | 1994 | 901 |
| 9 | The Dopamine Hypothesis of Schizophrenia: A Review* | Schizophrenia Bulletin | 1976 | 799 |
| 10 | Plasmid-Mediated Quinolone Resistance: a Multifaceted Threat | Clinical Microbiology Reviews | 2009 | 786 |
| 11 | Loneliness | Perspectives on Psychological Science | 2015 | 774 |
| 12 | American Association of Clinical Endocrinologists and American College of Endocrinology Guidelines for Management of Dyslipidemia and Prevention of Cardiovascular Disease | Endocrine Practice | 2017 | 766 |
| 13 | Insulin Biosynthesis: Evidence for a Precursor | Science | 1967 | 674 |
| 14 | Liver Transplantation in Children From Living Related Donors | Annals of Surgery | 1991 | 659 |
| 15 | Heart failure and mortality outcomes in patients with type 2 diabetes taking alogliptin versus placebo in EXAMINE: a multicentre, randomised, double-blind trial | Lancet, The | 2015 | 659 |
| 16 | The Pathogenesis and Treatment of Kidney Stones | New England Journal of Medicine | 1992 | 653 |
| 17 | Remodeling of the rat right and left ventricles in experimental hypertension. | Circulation Research | 1990 | 640 |
| 18 | Twenty-four-hour profiles and pulsatile patterns of insulin secretion in normal and obese subjects. | Journal of Clinical Investigation | 1988 | 618 |
| 19 | Perioperative Single Dose Systemic Dexamethasone for Postoperative Pain | Anesthesiology | 2011 | 609 |
| 20 | Application of Reduced-size Liver Transplants as Split Grafts, Auxiliary Orthotopic Grafts, and Living Related Segmental Transplants | Annals of Surgery | 1990 | 582 |
| 21 | Progress and Promise of FDG-PET Imaging for Cancer Patient Management and Oncologic Drug Development | Clinical Cancer Research | 2005 | 582 |
| 22 | Abnormal Patterns of Insulin Secretion in Non-Insulin-Dependent Diabetes Mellitus | New England Journal of Medicine | 1988 | 570 |
| 23 | Dysplasia-associated lesion or mass (DALM) detected by colonoscopy in long-standing ulcerative colitis: An indication for colectomy | Gastroenterology | 1981 | 542 |
| 24 | Critical evaluation of diagnostic aids for the detection of oral cancer | Oral Oncology | 2008 | 540 |
| 25 | Lipoprotein Management in Patients With Cardiometabolic Risk | Diabetes Care | 2008 | 536 |
| 26 | Functional Expression and Mutations of c-Met and Its Therapeutic Inhibition with SU11274 and Small Interfering RNA in Non–Small Cell Lung Cancer | Cancer Research | 2005 | 530 |
| 27 | Gene expression changes associated with progression and response in chronic myeloid leukemia | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 525 |
| 28 | Posaconazole as Salvage Therapy for Zygomycosis | Antimicrobial Agents and Chemotherapy | 2006 | 523 |
| 29 | Technique, indications, and clinical use of 24 hour esophageal pH monitoring | Journal of Thoracic and Cardiovascular Surgery | 1980 | 504 |
| 30 | On the Validity and Utility of Discriminating Among Impulsivity-Like Traits | Assessment | 2007 | 491 |
| 31 | ANGIO-IMMUNOBLASTIC LYMPHADENOPATHY WITH DYSPROTEINÆMIA | Lancet, The | 1974 | 488 |
| 32 | c-Met as a target for human cancer and characterization of inhibitors for therapeutic intervention | Cancer Letters | 2005 | 488 |
| 33 | Fibrillar collagen and myocardial stiffness in the intact hypertrophied rat left ventricle. | Circulation Research | 1989 | 482 |
| 34 | Perceptions of cancer patients and their physicians involved in phase I trials. | Journal of Clinical Oncology | 1995 | 481 |
| 35 | Developmental change in attention-deficit hyperactivity disorder in boys: A four-year longitudinal study | Journal of Abnormal Child Psychology | 1995 | 468 |
| 36 | Lipoprotein Management in Patients With Cardiometabolic Risk | Journal of the American College of Cardiology | 2008 | 466 |
| 37 | Cross-linking the major proteins of the isolated erythrocyte membrane | Journal of Molecular Biology | 1972 | 462 |
| 38 | Intensity-modulated whole pelvic radiotherapy in women with gynecologic malignancies | International Journal of Radiation Oncology Biology Physics | 2002 | 431 |
| 39 | The effect of the α-emitting radionuclide lead-212 on human ovarian carcinoma: A potential new form of therapy | Gynecologic Oncology | 1989 | 426 |
| 40 | Role of subconcussion in repetitive mild traumatic brain injury | Journal of Neurosurgery | 2013 | 424 |
| 41 | Polycystic Ovary Syndrome as a Form of FunctionalOvarian Hyperandrogenism Due to Dysregulation ofAndrogen Secretion* | Endocrine Reviews | 1995 | 416 |
| 42 | Inflammatory Bowel Disease | New England Journal of Medicine | 1996 | 416 |
| 43 | Metformin and Insulin Suppress Hepatic Gluconeogenesis through Phosphorylation of CREB Binding Protein | Cell | 2009 | 413 |
| 44 | Treatment of complex PTSD: Results of the ISTSS expert clinician survey on best practices | Journal of Traumatic Stress | 2011 | 383 |
| 45 | Guidelines for the Echocardiographic Assessment of Atrial Septal Defect and Patent Foramen Ovale: From the American Society of Echocardiography and Society for Cardiac Angiography and Interventions | Journal of the American Society of Echocardiography | 2015 | 379 |
| 46 | Quantitative study of insulin secretion and clearance in normal and obese subjects. | Journal of Clinical Investigation | 1988 | 373 |
| 47 | Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer | Nature Genetics | 2017 | 356 |
| 48 | Sodium Bicarbonate for the Treatment of Lactic Acidosis | Chest | 2000 | 354 |
| 49 | Metabolic fate of irinotecan in humans: correlation of glucuronidation with diarrhea | Cancer Research | 1994 | 350 |
| 50 | Consensus Guidelines for Delineation of Clinical Target Volume for Intensity-Modulated Pelvic Radiotherapy in Postoperative Treatment of Endometrial and Cervical Cancer | International Journal of Radiation Oncology Biology Physics | 2008 | 349 |
