| # | Title | Journal | Year | Citations |
|---|
| 1 | A copy number variation morbidity map of developmental delay | Nature Genetics | 2011 | 1,141 |
| 2 | Effect of Laparoscopic-Assisted Resection vs Open Resection of Stage II or III Rectal Cancer on Pathologic Outcomes | JAMA - Journal of the American Medical Association | 2015 | 898 |
| 3 | Omega-3 Polyunsaturated Fatty Acids and Cardiovascular Diseases | Journal of the American College of Cardiology | 2009 | 518 |
| 4 | Practice Guidelines for Outpatient Parenteral Antimicrobial Therapy | Clinical Infectious Diseases | 2004 | 487 |
| 5 | Adefovir dipivoxil for the treatment of lamivudine-resistant hepatitis B mutants | Hepatology | 2000 | 421 |
| 6 | A multicenter United States—Canadian trial to assess lamivudine monotherapy before and after liver transplantation for chronic hepatitis B | Hepatology | 2001 | 389 |
| 7 | Calcium channel blockers versus other antihypertensive therapies on progression of NIDDM associated nephropathy | Kidney International | 1996 | 375 |
| 8 | Initial clinical experience with the MammoSite breast brachytherapy applicator in women with early-stage breast cancer treated with breast-conserving therapy | International Journal of Radiation Oncology Biology Physics | 2003 | 373 |
| 9 | Accelerator beam data commissioning equipment and procedures: Report of the TG‐106 of the Therapy Physics Committee of the AAPM | Medical Physics | 2008 | 370 |
| 10 | Obesity and its effect on survival in patients undergoing orthotopic liver transplantation in the United States | Hepatology | 2002 | 367 |
| 11 | Pathological diagnosis of chronic hepatitis C: A multicenter comparative study with chronic hepatitis B | Gastroenterology | 1993 | 365 |
| 12 | Clinicopathological staging for colorectal cancer: An International Documentation System (IDS) and an International Comprehensive Anatomical Terminology (ICAT) | Journal of Gastroenterology and Hepatology (Australia) | 1991 | 357 |
| 13 | Effect of cilostazol on walking distances in patients with intermittent claudication caused by peripheral vascular disease | Journal of Vascular Surgery | 1998 | 322 |
| 14 | Opportunistic Mycelial Fungal Infections in Organ Transplant Recipients: Emerging Importance of Non-Aspergillus Mycelial Fungi | Clinical Infectious Diseases | 2003 | 321 |
| 15 | CHRONIC EOSINOPHILIA DUE TO VISCERAL LARVA MIGRANS | Pediatrics | 1952 | 309 |
| 16 | Improved left ventricular endocardial border delineation and opacification with OPTISON (FS069), a new echocardiographic contrast agent | Journal of the American College of Cardiology | 1998 | 303 |
| 17 | Long-term mortality and morbidity of transfusion-associated non-A, non-B, and type C hepatitis: A National Heart, Lung, and Blood Institute collaborative study | Hepatology | 2001 | 286 |
| 18 | Multicenter study of lamivudine therapy for hepatitis B after liver transplantation | Hepatology | 1999 | 281 |
| 19 | Dietary salt intake. A determinant of cardiac involvement in essential hypertension. | Circulation | 1988 | 271 |
| 20 | Determinants of early mortality in patients with decompensated chronic hepatitis B treated with antiviral therapy | Gastroenterology | 2002 | 266 |
| 21 | Liver transplantation for “very early” intrahepatic cholangiocarcinoma: International retrospective study supporting a prospective assessment | Hepatology | 2016 | 262 |
| 22 | Benefits of Cardiac Rehabilitation and Exercise Training | Chest | 2000 | 256 |
| 23 | Benefits of cardiac rehabilitation and exercise training in secondary coronary prevention in the elderly | Journal of the American College of Cardiology | 1993 | 243 |
| 24 | Efficacy and Safety of Inhaled Insulin (Exubera) Compared With Subcutaneous Insulin Therapy in Patients With Type 2 Diabetes: Results of a 6-month, randomized, comparative trial | Diabetes Care | 2004 | 240 |
| 25 | Enalapril improves systemic and renal hemodynamics and allows regression of left ventricular mass in essential hypertension | American Journal of Cardiology | 1984 | 236 |
| 26 | Five-year results: the initial clinical trial of Mammosite balloon brachytherapy for partial breast irradiation in early-stage breast cancer | American Journal of Surgery | 2007 | 231 |
| 27 | Exercise Training and Cardiac Rehabilitation in Primary and Secondary Prevention of Coronary Heart Disease | Mayo Clinic Proceedings | 2009 | 230 |
| 28 | Carotid duplex sonography: a multicenter recommendation for standardized imaging and Doppler criteria. | Radiographics | 1988 | 228 |
| 29 | Anorectal melanoma | Cancer | 1981 | 223 |
| 30 | Rectal carcinoids | Diseases of the Colon and Rectum | 1992 | 217 |
| 31 | Vasopeptidase inhibition and angio-oedema | Lancet, The | 2000 | 215 |
| 32 | Zenith AAA endovascular graft: intermediate-term results of the US multicenter trial | Journal of Vascular Surgery | 2004 | 215 |
| 33 | Hyaluronic acid fillers | Dermatologic Therapy | 2006 | 212 |
| 34 | Recommended indications for operative treatment of abdominal aortic aneurysms | Journal of Vascular Surgery | 1992 | 204 |
| 35 | Effects of cardiac rehabilitation and exercise training programs on depression in patients after major coronary events | American Heart Journal | 1996 | 203 |
| 36 | Unstable Angina | Circulation | 1995 | 199 |
| 37 | Diabetic cardiomyopathy - A comprehensive updated review | Progress in Cardiovascular Diseases | 2019 | 197 |
| 38 | Exercise Training and Cardiac Rehabilitation in Primary and Secondary Prevention of Coronary Heart Disease | Mayo Clinic Proceedings | 2009 | 193 |
| 39 | Incidence of small-bowel obstruction and adhesiolysis after open colorectal and general surgery | Diseases of the Colon and Rectum | 1999 | 189 |
| 40 | Prevalence of HBV precore/core promoter variants in the United States | Hepatology | 2003 | 185 |
| 41 | A Statistical Theory of Cell Killing by Radiation of Varying Linear Energy Transfer | Radiation Research | 1994 | 182 |
| 42 | Renal Artery Stent Placement: Utility in Lesions Difficult to Treat With Balloon Angioplasty | Journal of the American College of Cardiology | 1997 | 182 |
| 43 | Acute Flaccid Paralysis and West Nile Virus Infection | Emerging Infectious Diseases | 2003 | 180 |
| 44 | Doppler color flow imaging | Journal of Clinical Ultrasound | 1987 | 178 |
| 45 | Effects of cardiac rehabilitation and exercise training on exercise capacity, coronary risk factors, behavioral characteristics, and quality of life in women | American Journal of Cardiology | 1995 | 172 |
| 46 | Nifedipine and Mortality | Circulation | 1995 | 167 |
| 47 | Coronary Thrombi Increase PTCA Risk | Circulation | 1996 | 166 |
| 48 | A Phase II Trial of Brachytherapy Alone After Lumpectomy for Select Breast Cancer: Tumor Control and Survival Outcomes of RTOG 95-17 | International Journal of Radiation Oncology Biology Physics | 2008 | 163 |
| 49 | INVASIVE ASPERGILLOSIS IN LIVER TRANSPLANT RECIPIENTS IN THE 1990s | Transplantation | 1997 | 160 |
| 50 | Patient‐directed titration for achieving glycaemic goals using a once‐daily basal insulin analogue: an assessment of two different fasting plasma glucose targets ‐ the TITRATETM study | Diabetes, Obesity and Metabolism | 2009 | 158 |
