| # | Title | Journal | Year | Citations |
|---|
| 1 | Defining community acquired pneumonia severity on presentation to hospital: an international derivation and validation study | Thorax | 2003 | 2,415 |
| 2 | Differential oestrogen receptor binding is associated with clinical outcome in breast cancer | Nature | 2012 | 1,655 |
| 3 | OARSI recommendations for the management of hip and knee osteoarthritis | Osteoarthritis and Cartilage | 2010 | 1,330 |
| 4 | Rapid Entire Body Assessment (REBA) | Applied Ergonomics | 2000 | 1,323 |
| 5 | Preoperative radiotherapy versus selective postoperative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC-CTG C016): a multicentre, randomised trial | Lancet, The | 2009 | 1,292 |
| 6 | The Nottingham prognostic index in primary breast cancer | Breast Cancer Research and Treatment | 1992 | 913 |
| 7 | Effect of the plane of surgery achieved on local recurrence in patients with operable rectal cancer: a prospective study using data from the MRC CR07 and NCIC-CTG CO16 randomised clinical trial | Lancet, The | 2009 | 906 |
| 8 | Diagnosis and management of adult coeliac disease: guidelines from the British Society of Gastroenterology | Gut | 2014 | 870 |
| 9 | Ovarian cancer screening and mortality in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): a randomised controlled trial | Lancet, The | 2016 | 791 |
| 10 | Sensitivity and specificity of multimodal and ultrasound screening for ovarian cancer, and stage distribution of detected cancers: results of the prevalence screen of the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) | Lancet Oncology, The | 2009 | 738 |
| 11 | A Comparison of Omeprazole with Ranitidine for Ulcers Associated with Nonsteroidal Antiinflammatory Drugs | New England Journal of Medicine | 1998 | 723 |
| 12 | A body image scale for use with cancer patients | European Journal of Cancer | 2001 | 669 |
| 13 | Measuring quality of life: Is quality of life determined by expectations or experience? | BMJ: British Medical Journal | 2001 | 622 |
| 14 | Anastrozole is superior to tamoxifen as first-line therapy in hormone receptor positive advanced breast carcinoma | Cancer | 2001 | 572 |
| 15 | Comparison of psychological aspects and patient satisfaction following breast conserving surgery, simple mastectomy and breast reconstruction | European Journal of Cancer | 2000 | 554 |
| 16 | Osteoarthritis, angiogenesis and inflammation | British Journal of Rheumatology | 2005 | 544 |
| 17 | The prevalence of vitamin D inadequacy amongst women with osteoporosis: an international epidemiological investigation | Journal of Internal Medicine | 2006 | 504 |
| 18 | Phase II Study of Temsirolimus (CCI-779), a Novel Inhibitor of mTOR, in Heavily Pretreated Patients With Locally Advanced or Metastatic Breast Cancer | Journal of Clinical Oncology | 2005 | 461 |
| 19 | Effects of Risedronate Treatment on Bone Density and Vertebral Fracture in Patients on Corticosteroid Therapy | Calcified Tissue International | 2000 | 457 |
| 20 | Evidence-based recommendations for the role of exercise in the management of osteoarthritis of the hip or knee--the MOVE consensus | British Journal of Rheumatology | 2005 | 440 |
| 21 | Measuring quality of life: Are quality of life measures patient centred? | BMJ: British Medical Journal | 2001 | 437 |
| 22 | Study of community acquired pneumonia aetiology (SCAPA) in adults admitted to hospital: implications for management guidelines | Thorax | 2001 | 432 |
| 23 | The rising incidence of idiopathic pulmonary fibrosis in the UK | Thorax | 2011 | 427 |
| 24 | A systematic review of the ultrasound estimation of fetal weight | Ultrasound in Obstetrics and Gynecology | 2005 | 423 |
| 25 | The psychological impact of immediate rather than delayed breast reconstruction | European Journal of Surgical Oncology | 2000 | 405 |
| 26 | Influence of patients' expectations on antibiotic management of acute lower respiratory tract illness in general practice: questionnaire study | BMJ: British Medical Journal | 1997 | 402 |
| 27 | Increased Risk of Myocardial Infarction and Stroke Following Exacerbation of COPD | Chest | 2010 | 398 |
| 28 | Induction versus expectant monitoring for intrauterine growth restriction at term: randomised equivalence trial (DIGITAT) | BMJ: British Medical Journal | 2010 | 375 |
| 29 | Aerobic walking or strengthening exercise for osteoarthritis of the knee? A systematic review | Annals of the Rheumatic Diseases | 2005 | 371 |
| 30 | A randomised prospective comparison of percutaneous endoscopic gastrostomy and nasogastric tube feeding after acute dysphagic stroke | BMJ: British Medical Journal | 1996 | 370 |
| 31 | Guidelines for radiologically guided lung biopsy | Thorax | 2003 | 359 |
| 32 | Angiogenesis and nerve growth factor at the osteochondral junction in rheumatoid arthritis and osteoarthritis | Rheumatology | 2010 | 347 |
| 33 | T-cell acute lymphoblastic leukemia in adults: clinical features, immunophenotype, cytogenetics, and outcome from the large randomized prospective trial (UKALL XII/ECOG 2993) | Blood | 2009 | 346 |
| 34 | Meta-analysis of randomized clinical trials comparing open and laparoscopic inguinal hernia repair | British Journal of Surgery | 2003 | 340 |
| 35 | Diagnosis and treatment of primary CNS lymphoma in immunocompetent patients: guidelines from the European Association for Neuro-Oncology | Lancet Oncology, The | 2015 | 340 |
| 36 | Pulmonary actinomycosis | European Respiratory Journal | 2003 | 318 |
| 37 | Ovarian cancer population screening and mortality after long-term follow-up in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): a randomised controlled trial | Lancet, The | 2021 | 313 |
| 38 | Seven-year outcome in the RITA-2 trial: coronary angioplasty versus medical therapy | Journal of the American College of Cardiology | 2003 | 307 |
| 39 | Fulvestrant versus anastrozole for the treatment of advanced breast carcinoma in postmenopausal women | Cancer | 2003 | 305 |
| 40 | Expression of mucins (MUC1, MUC2, MUC3, MUC4, MUC5AC and MUC6) and their prognostic significance in human breast cancer | Modern Pathology | 2005 | 305 |
| 41 | Gemcitabine and capecitabine with or without telomerase peptide vaccine GV1001 in patients with locally advanced or metastatic pancreatic cancer (TeloVac): an open-label, randomised, phase 3 trial | Lancet Oncology, The | 2014 | 296 |
| 42 | The role of proteases in transforming growth factor-β activation | International Journal of Biochemistry and Cell Biology | 2008 | 295 |
| 43 | Malignancy and mortality in people with coeliac disease: population based cohort study | BMJ: British Medical Journal | 2004 | 294 |
| 44 | First-line selective internal radiotherapy plus chemotherapy versus chemotherapy alone in patients with liver metastases from colorectal cancer (FOXFIRE, SIRFLOX, and FOXFIRE-Global): a combined analysis of three multicentre, randomised, phase 3 trials | Lancet Oncology, The | 2017 | 293 |
| 45 | Self-medication with Antimicrobial Drugs in Europe | Emerging Infectious Diseases | 2006 | 292 |
| 46 | Exposure to invasive procedures in neonatal intensive care unit admissions. | Archives of Disease in Childhood: Fetal and Neonatal Edition | 1995 | 288 |
| 47 | A UK Consensus Group on management of glucocorticoid-induced osteoporosis: an update | Journal of Internal Medicine | 1998 | 287 |
| 48 | Prior SARS-CoV-2 infection rescues B and T cell responses to variants after first vaccine dose | Science | 2021 | 286 |
| 49 | Male involvement and maternal health outcomes: systematic review and meta-analysis | Journal of Epidemiology and Community Health | 2015 | 281 |
| 50 | Oncological and cosmetic outcomes of oncoplastic breast conserving surgery | European Journal of Surgical Oncology | 2005 | 280 |
