| # | Title | Journal | Year | Citations |
|---|
| 1 | The myths of laparoscopic surgery | American Journal of Obstetrics and Gynecology | 2000 | 1,475 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 3 | A unique view on male infertility around the globe | Reproductive Biology and Endocrinology | 2015 | 1,387 |
| 4 | Career Adapt-Abilities Scale: Construction, reliability, and measurement equivalence across 13 countries | Journal of Vocational Behavior | 2012 | 1,301 |
| 5 | CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2009–2013 | Neuro-Oncology | 2016 | 995 |
| 6 | Bile Acid Metabolism and Signaling | | 2013 | 994 |
| 7 | Approaching a consensus cognitive battery for clinical trials in schizophrenia: The NIMH-MATRICS conference to select cognitive domains and test criteria | Biological Psychiatry | 2004 | 818 |
| 8 | Two components of long-term potentiation induced by different patterns of afferent activation | Nature | 1990 | 684 |
| 9 | Ischemia and No Obstructive Coronary Artery Disease (INOCA) | Circulation | 2017 | 527 |
| 10 | Colistin Versus Ceftazidime-Avibactam in the Treatment of Infections Due to Carbapenem-Resistant Enterobacteriaceae | Clinical Infectious Diseases | 2018 | 485 |
| 11 | Neural stem cells display an inherent mechanism for rescuing dysfunctional neurons | Nature Biotechnology | 2002 | 467 |
| 12 | Cardiac Mitochondria and Reactive Oxygen Species Generation | Circulation Research | 2014 | 449 |
| 13 | Clinical Practice Guidelines by the Infectious Diseases Society of America: 2018 Update on Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management of Seasonal Influenzaa | Clinical Infectious Diseases | 2019 | 449 |
| 14 | Cancer Prevention and Treatment with Resveratrol: From Rodent Studies to Clinical Trials | Cancer Prevention Research | 2009 | 443 |
| 15 | Nano-microparticles as immune adjuvants: correlating particle sizes and the resultant immune responses | Expert Review of Vaccines | 2010 | 443 |
| 16 | The McMaster Model of Family Functioning | Journal of Marital and Family Therapy | 1978 | 434 |
| 17 | Regulation of bile acid synthesis: pathways, nuclear receptors, and mechanisms | Journal of Hepatology | 2004 | 433 |
| 18 | Racial Differences in Survival From Breast Cancer | JAMA - Journal of the American Medical Association | 1994 | 415 |
| 19 | Bile Acid Regulation of Gene Expression: Roles of Nuclear Hormone Receptors | Endocrine Reviews | 2002 | 409 |
| 20 | Systematic review of the literature on assessment, feedback and physicians’ clinical performance: BEME Guide No. 7 | Medical Teacher | 2006 | 404 |
| 21 | Life Design: A Paradigm for Career Intervention in the 21st Century | Journal of Counseling and Development | 2012 | 399 |
| 22 | The Pains of Endometriosis | Science | 2005 | 392 |
| 23 | A multicenter, randomized study comparing the efficacy and safety of intravenous and/or oral levofloxacin versus ceftriaxone and/or cefuroxime axetil in treatment of adults with community-acquired pneumonia | Antimicrobial Agents and Chemotherapy | 1997 | 356 |
| 24 | Mechanism of tissue-specific farnesoid X receptor in suppressing the expression of genes in bile-acid synthesis in mice | Hepatology | 2012 | 349 |
| 25 | Intestine farnesoid X receptor agonist and the gut microbiota activate G‐protein bile acid receptor‐1 signaling to improve metabolism | Hepatology | 2018 | 348 |
| 26 | Child vocational development: A review and reconsideration | Journal of Vocational Behavior | 2005 | 347 |
| 27 | An improved and rapid HPLC-EC method for the isocratic separation of amino acid neurotransmitters from brain tissue and microdialysis perfusates | Life Sciences | 1988 | 331 |
| 28 | Bile acids activate fibroblast growth factor 19 signaling in human hepatocytes to inhibit cholesterol 7α-hydroxylase gene expression | Hepatology | 2009 | 331 |
| 29 | Regulation of cholesterol 7α-hydroxylase gene ( CYP7A1 ) transcription by the liver orphan receptor (LXRα) | Gene | 2001 | 329 |
| 30 | Gonadal steroids: effects on excitability of hippocampal pyramidal cells | Science | 1980 | 311 |
| 31 | Bile Acid Metabolism in Liver Pathobiology | Gene Expression | 2018 | 308 |
| 32 | Executive Summary: IDSA Clinical Practice Guideline for Acute Bacterial Rhinosinusitis in Children and Adults | Clinical Infectious Diseases | 2012 | 299 |
| 33 | Regulation of bile acid synthesis | Frontiers in Bioscience - Landmark | 1998 | 277 |
| 34 | Whales originated from aquatic artiodactyls in the Eocene epoch of India | Nature | 2007 | 276 |
| 35 | Farnesoid X Receptor Responds to Bile Acids and Represses Cholesterol 7α-Hydroxylase Gene (CYP7A1) Transcription | Journal of Biological Chemistry | 2000 | 267 |
| 36 | Triterpenoids as potential agents for the chemoprevention and therapy of breast cancer | Frontiers in Bioscience - Landmark | 2011 | 265 |
| 37 | Neurotoxicity of pesticides | Acta Neuropathologica | 2019 | 265 |
| 38 | Oxidative stress and inflammation in osteoarthritis pathogenesis: Role of polyphenols | Biomedicine and Pharmacotherapy | 2020 | 264 |
| 39 | Skeletons of terrestrial cetaceans and the relationship of whales to artiodactyls | Nature | 2001 | 255 |
| 40 | Efferent connections of the lateral hypothalamic area of the rat: An autoradiographic investigation | Brain Research Bulletin | 1982 | 254 |
| 41 | Place conditioning reveals the rewarding aspect of social interaction in juvenile rats | Physiology and Behavior | 1992 | 254 |
| 42 | Cytochrome P450 omega hydroxylase (CYP4) function in fatty acid metabolism and metabolic diseases | Biochemical Pharmacology | 2008 | 251 |
| 43 | Clinical Practice Guidelines by the Infectious Diseases Society of America: 2018 Update on Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management of Seasonal Influenzaa | Clinical Infectious Diseases | 2019 | 251 |
| 44 | Terpenoids as potential chemopreventive and therapeutic agents in liver cancer | World Journal of Hepatology | 2011 | 249 |
| 45 | Discussing Spirituality With Patients: A Rational and Ethical Approach | Annals of Family Medicine | 2004 | 245 |
| 46 | Epidemiology, microbiology, and treatment considerations for bacterial pneumonia complicating influenza | International Journal of Infectious Diseases | 2012 | 244 |
| 47 | Impact of Circadian Nuclear Receptor REV-ERBα on Midbrain Dopamine Production and Mood Regulation | Cell | 2014 | 242 |
| 48 | Single versus multiple fractions of repeat radiation for painful bone metastases: a randomised, controlled, non-inferiority trial | Lancet Oncology, The | 2014 | 239 |
| 49 | Bile Acids as Metabolic Regulators and Nutrient Sensors | Annual Review of Nutrition | 2019 | 233 |
| 50 | Geriatric Emergency Department Guidelines | Annals of Emergency Medicine | 2014 | 228 |
