| # | Title | Journal | Year | Citations |
|---|
| 1 | Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area | JAMA - Journal of the American Medical Association | 2020 | 7,474 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 3 | A Genome-Wide Association Study Identifies IL23R as an Inflammatory Bowel Disease Gene | Science | 2006 | 2,739 |
| 4 | Strong Association of De Novo Copy Number Mutations with Autism | Science | 2007 | 2,497 |
| 5 | Guidelines for the Prevention of Intravascular Catheter-related Infections | Clinical Infectious Diseases | 2011 | 2,242 |
| 6 | Incorporation of Bevacizumab in the Primary Treatment of Ovarian Cancer | New England Journal of Medicine | 2011 | 2,011 |
| 7 | Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus | Proceedings of the National Academy of Sciences of the United States of America | 2003 | 1,978 |
| 8 | Genetics of rheumatoid arthritis contributes to biology and drug discovery | Nature | 2014 | 1,974 |
| 9 | The gut microbiota influences blood-brain barrier permeability in mice | Science Translational Medicine | 2014 | 1,589 |
| 10 | Chronic Lymphocytic Leukemia | New England Journal of Medicine | 2005 | 1,443 |
| 11 | A phase III, randomized, placebo-controlled study of belimumab, a monoclonal antibody that inhibits B lymphocyte stimulator, in patients with systemic lupus erythematosus | Arthritis and Rheumatism | 2011 | 1,277 |
| 12 | Targeting potential drivers of COVID-19: Neutrophil extracellular traps | Journal of Experimental Medicine | 2020 | 1,193 |
| 13 | Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci | Nature Genetics | 2010 | 1,132 |
| 14 | Efficacy and safety of rituximab in patients with active proliferative lupus nephritis: The lupus nephritis assessment with rituximab study | Arthritis and Rheumatism | 2012 | 1,083 |
| 15 | Prevalence, incidence and mortality from cardiovascular disease in patients with pooled and specific severe mental illness: a large‐scale meta‐analysis of 3,211,768 patients and 113,383,368 controls | World Psychiatry | 2017 | 1,082 |
| 16 | Vagus nerve stimulation therapy for partial-onset seizures | Neurology | 1998 | 1,070 |
| 17 | Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trial | Lancet, The | 2007 | 949 |
| 18 | STROCSS 2021: Strengthening the reporting of cohort, cross-sectional and case-control studies in surgery | International Journal of Surgery | 2021 | 938 |
| 19 | Definition of clinically relevant non‐major bleeding in studies of anticoagulants in atrial fibrillation and venous thromboembolic disease in non‐surgical patients: communication from the SSC of the ISTH | Journal of Thrombosis and Haemostasis | 2015 | 889 |
| 20 | Cardiometabolic Risk of Second-Generation Antipsychotic Medications During First-Time Use in Children and Adolescents | JAMA - Journal of the American Medical Association | 2009 | 867 |
| 21 | Endogenous HMGB1 regulates autophagy | Journal of Cell Biology | 2010 | 819 |
| 22 | US Spending on Personal Health Care and Public Health, 1996-2013 | JAMA - Journal of the American Medical Association | 2016 | 810 |
| 23 | Neuropsychology of First-Episode Schizophrenia: Initial Characterization and Clinical Correlates | American Journal of Psychiatry | 2000 | 809 |
| 24 | Phlorizin: a review | Diabetes/Metabolism Research and Reviews | 2005 | 772 |
| 25 | Hyperthyroidism and Other Causes of Thyrotoxicosis: Management Guidelines of the American Thyroid Association and American Association of Clinical Endocrinologists | Thyroid | 2011 | 771 |
| 26 | Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis | Nature Genetics | 2012 | 768 |
| 27 | A multicenter trial of 6-mercaptopurine and prednisone in children with newly diagnosed Crohn's disease | Gastroenterology | 2000 | 761 |
| 28 | Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry | Nature Immunology | 2019 | 760 |
| 29 | Chronic lymphocytic leukemia B cells express restricted sets of mutated and unmutated antigen receptors. | Journal of Clinical Investigation | 1998 | 759 |
| 30 | Induction and Maintenance Infliximab Therapy for the Treatment of Moderate-to-Severe Crohn’s Disease in Children | Gastroenterology | 2007 | 754 |
| 31 | TRAF1–C5as a Risk Locus for Rheumatoid Arthritis — A Genomewide Study | New England Journal of Medicine | 2007 | 729 |
| 32 | A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus | Nature Genetics | 2009 | 729 |
| 33 | CPX-351 (cytarabine and daunorubicin) Liposome for Injection Versus Conventional Cytarabine Plus Daunorubicin in Older Patients With Newly Diagnosed Secondary Acute Myeloid Leukemia | Journal of Clinical Oncology | 2018 | 682 |
| 34 | Lower Risk for Tardive Dyskinesia Associated With Second-Generation Antipsychotics: A Systematic Review of 1-Year Studies | American Journal of Psychiatry | 2004 | 653 |
| 35 | Genome-wide association study in alopecia areata implicates both innate and adaptive immunity | Nature | 2010 | 651 |
| 36 | Estrogen-Receptor Status and Outcomes of Modern Chemotherapy for Patients With Node-Positive Breast Cancer | JAMA - Journal of the American Medical Association | 2006 | 645 |
| 37 | Macrophage Migration Inhibitory Factor Provides Cardioprotection During Ischemia/Reperfusion by Reducing Oxidative Stress | Antioxidants and Redox Signaling | 2011 | 636 |
| 38 | Splenectomy inactivates the cholinergic antiinflammatory pathway during lethal endotoxemia and polymicrobial sepsis | Journal of Experimental Medicine | 2006 | 630 |
| 39 | Insulin Resistance and Hyperinsulinemia | Diabetes Care | 2008 | 611 |
| 40 | A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus | Nature Genetics | 2006 | 593 |
| 41 | AAV2-GAD gene therapy for advanced Parkinson's disease: a double-blind, sham-surgery controlled, randomised trial | Lancet Neurology, The | 2011 | 582 |
| 42 | erbB-2, p53, and Efficacy of Adjuvant Therapy in Lymph Node-Positive Breast Cancer | Journal of the National Cancer Institute | 1998 | 572 |
| 43 | High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis | Nature Genetics | 2012 | 558 |
| 44 | Brexanolone injection in post-partum depression: two multicentre, double-blind, randomised, placebo-controlled, phase 3 trials | Lancet, The | 2018 | 547 |
| 45 | Reversing Established Sepsis in Rats with Human Vasoactive Hormone Adrenomedullin and its Binding Protein | Molecular Medicine | 2009 | 546 |
| 46 | Pervasive Sharing of Genetic Effects in Autoimmune Disease | PLoS Genetics | 2011 | 540 |
| 47 | Dose and Dose Intensity as Determinants of Outcome in the Adjuvant Treatment of Breast Cancer | Journal of the National Cancer Institute | 1998 | 537 |
| 48 | Use of GRADE for assessment of evidence about prognosis: rating confidence in estimates of event rates in broad categories of patients | BMJ, The | 2015 | 532 |
| 49 | Bronchogenic carcinoma: analysis of staging in the mediastinum with CT by correlative lymph node mapping and sampling. | Radiology | 1992 | 528 |
| 50 | Comparison of Early Intervention Services vs Treatment as Usual for Early-Phase Psychosis | JAMA Psychiatry | 2018 | 516 |
