| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 2 | Deep Learning Applications in Medical Image Analysis | IEEE Access | 2018 | 903 |
| 3 | Ischaemic stroke | Nature Reviews Disease Primers | 2019 | 849 |
| 4 | Midbrain-like Organoids from Human Pluripotent Stem Cells Contain Functional Dopaminergic and Neuromelanin-Producing Neurons | Cell Stem Cell | 2016 | 628 |
| 5 | Parkinson's disease-associated mutations in LRRK2 link enhanced GTP-binding and kinase activities to neuronal toxicity | Human Molecular Genetics | 2007 | 535 |
| 6 | BrdU immunohistochemistry for studying adult neurogenesis: Paradigms, pitfalls, limitations, and validation | Brain Research Reviews | 2007 | 532 |
| 7 | Disease-causing mutations in Parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy | Journal of Cell Biology | 2010 | 483 |
| 8 | Diagnosis and management of Guillain–Barré syndrome in ten steps | Nature Reviews Neurology | 2019 | 463 |
| 9 | Intraepidermal nerve fiber density at the distal leg: a worldwide normative reference study | Journal of the Peripheral Nervous System | 2010 | 462 |
| 10 | Parkinson’s disease: etiopathogenesis and treatment | Journal of Neurology, Neurosurgery and Psychiatry | 2020 | 459 |
| 11 | Outbreak of Nipah-virus infection among abattoir workers in Singapore | Lancet, The | 1999 | 388 |
| 12 | Lysine 63-linked ubiquitination promotes the formation and autophagic clearance of protein inclusions associated with neurodegenerative diseases | Human Molecular Genetics | 2008 | 379 |
| 13 | Calmodulin bifurcates the local Ca2+ signal that modulates P/Q-type Ca2+ channels | Nature | 2001 | 371 |
| 14 | A 3D neurovascular microfluidic model consisting of neurons, astrocytes and cerebral endothelial cells as a blood–brain barrier | Lab on A Chip | 2017 | 338 |
| 15 | Extending thrombolysis to 4·5–9 h and wake-up stroke using perfusion imaging: a systematic review and meta-analysis of individual patient data | Lancet, The | 2019 | 321 |
| 16 | Non-invasive measurement of perfusion: a critical review of arterial spin labelling techniques | British Journal of Radiology | 2006 | 300 |
| 17 | Differential Diagnosis for Bilateral Abnormalities of the Basal Ganglia and Thalamus | Radiographics | 2011 | 289 |
| 18 | A Large Clinical Study on the Ability of Stroke Patients to Use an EEG-Based Motor Imagery Brain-Computer Interface | Clinical EEG and Neuroscience | 2011 | 289 |
| 19 | Intraparticle Energy Level Alignment of Semiconducting Polymer Nanoparticles to Amplify Chemiluminescence for Ultrasensitive In Vivo Imaging of Reactive Oxygen Species | ACS Nano | 2016 | 288 |
| 20 | Model-free arterial spin labeling quantification approach for perfusion MRI | Magnetic Resonance in Medicine | 2006 | 275 |
| 21 | Cancer stem cell: target for anti‐cancer therapy | FASEB Journal | 2007 | 241 |
| 22 | Sarcoma classification by DNA methylation profiling | Nature Communications | 2021 | 237 |
| 23 | Perfusion Imaging Using Arterial Spin Labeling | Topics in Magnetic Resonance Imaging | 2004 | 234 |
| 24 | Large artery ischaemic stroke in severe acute respiratory syndrome (SARS) | Journal of Neurology | 2004 | 222 |
| 25 | Resting State Changes in Functional Connectivity Correlate With Movement Recovery for BCI and Robot-Assisted Upper-Extremity Training After Stroke | Neurorehabilitation and Neural Repair | 2013 | 215 |
| 26 | COVID-19 and ischemic stroke: a systematic review and meta-summary of the literature | Journal of Thrombosis and Thrombolysis | 2020 | 214 |
| 27 | The landscape of genetic diseases in Saudi Arabia based on the first 1000 diagnostic panels and exomes | Human Genetics | 2017 | 209 |
| 28 | Stress-induced alterations in parkin solubility promote parkin aggregation and compromise parkin's protective function | Human Molecular Genetics | 2005 | 201 |
| 29 | Cholinergic–serotonergic imbalance contributes to cognitive and behavioral symptoms in Alzheimer’s disease | Neuropsychologia | 2005 | 193 |
| 30 | Parkin Protects against LRRK2 G2019S Mutant-Induced Dopaminergic Neurodegeneration in Drosophila | Journal of Neuroscience | 2009 | 193 |
| 31 | Human Bone Marrow-Derived Mesenchymal Stem Cells Suppress Human Glioma Growth Through Inhibition of Angiogenesis | Stem Cells | 2013 | 192 |
| 32 | Diffusion-Weighted MR Imaging: Diagnosing Atypical or Malignant Meningiomas and Detecting Tumor Dedifferentiation | American Journal of Neuroradiology | 2008 | 188 |
| 33 | Effects of Head Posture on Cerebral Hemodynamics: Its Influences on Intracranial Pressure, Cerebral Perfusion Pressure, and Cerebral Oxygenation | Neurosurgery | 2004 | 187 |
| 34 | Clinical genomics expands the morbid genome of intellectual disability and offers a high diagnostic yield | Molecular Psychiatry | 2017 | 187 |
| 35 | Extensive diversity in circadian regulation of plasma lipids and evidence for different circadian metabolic phenotypes in humans | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 186 |
| 36 | Hemodynamics of Cerebral Aneurysm Initiation: The Role of Wall Shear Stress and Spatial Wall Shear Stress Gradient | American Journal of Neuroradiology | 2011 | 185 |
| 37 | Selection and Evaluation of Tagging SNPs in the Neuronal-Sodium-Channel Gene SCN1A: Implications for Linkage-Disequilibrium Gene Mapping | American Journal of Human Genetics | 2003 | 181 |
| 38 | Management of acute ischemic stroke in patients with COVID-19 infection: Report of an international panel | International Journal of Stroke | 2020 | 179 |
| 39 | A sensitive two-photon probe to selectively detect monoamine oxidase B activity in Parkinson’s disease models | Nature Communications | 2014 | 175 |
| 40 | Age at symptom onset and death and disease duration in genetic frontotemporal dementia: an international retrospective cohort study | Lancet Neurology, The | 2020 | 175 |
| 41 | Historical Perspective: Models of Parkinson’s Disease | International Journal of Molecular Sciences | 2020 | 174 |
| 42 | Peripheral nerve regeneration with sustained release of poly(phosphoester) microencapsulated nerve growth factor within nerve guide conduits | Biomaterials | 2003 | 172 |
| 43 | The Infarct Core is Well Represented by the Acute Diffusion Lesion: Sustained Reversal is Infrequent | Journal of Cerebral Blood Flow and Metabolism | 2012 | 172 |
| 44 | Identification of Risk Loci for Parkinson Disease in Asians and Comparison of Risk Between Asians and Europeans | JAMA Neurology | 2020 | 170 |
| 45 | Irditoxin, a novel covalently linked heterodimeric three‐finger toxin with high taxon‐specific neurotoxicity | FASEB Journal | 2009 | 165 |
| 46 | Nipah Virus Infection | Journal of Clinical Microbiology | 2018 | 162 |
| 47 | Excessive daytime sleepiness in obstructive sleep apnea: prevalence, severity, and predictors | Sleep Medicine | 2004 | 161 |
| 48 | The LRRK2 Gly2385Arg variant is associated with Parkinson’s disease: genetic and functional evidence | Human Genetics | 2007 | 157 |
| 49 | AMP Kinase Activation Mitigates Dopaminergic Dysfunction and Mitochondrial Abnormalities inDrosophilaModels of Parkinson's Disease | Journal of Neuroscience | 2012 | 155 |
| 50 | The G2019S LRRK2 mutation is uncommon in an Asian cohort of Parkinson's disease patients | Neuroscience Letters | 2005 | 153 |
