| Major increases in opioid analgesic abuse in the United States: concerns and strategies | Drug and Alcohol Dependence | 2006 | 644 |
| Cannabinoid CB2 receptors: immunohistochemical localization in rat brain | Brain Research | 2006 | 618 |
| Lifetime comorbidity of DSM-IV mood and anxiety disorders and specific drug use disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions | Journal of Clinical Psychiatry | 2006 | 616 |
| Drug addiction: the neurobiology of disrupted self-control | Trends in Molecular Medicine | 2006 | 424 |
| Abuse of prescription drugs and the risk of addiction | Drug and Alcohol Dependence | 2006 | 386 |
| Discovery of the presence and functional expression of cannabinoid CB2 receptors in brain | Annals of the New York Academy of Sciences | 2006 | 386 |
| Role of brain dopamine in food reward and reinforcement | Philosophical Transactions of the Royal Society B: Biological Sciences | 2006 | 308 |
| Cigarette smoking saturates brain alpha 4 beta 2 nicotinic acetylcholine receptors | Archives of General Psychiatry | 2006 | 302 |
| High levels of dopamine D2 receptors in unaffected members of alcoholic families: possible protective factors | Archives of General Psychiatry | 2006 | 269 |
| Changes in the prevalence of major depression and comorbid substance use disorders in the United States between 1991-1992 and 2001-2002 | American Journal of Psychiatry | 2006 | 267 |
| Kappa opioids selectively control dopaminergic neurons projecting to the prefrontal cortex | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 257 |
| Characterization of a mouse strain expressing Cre recombinase from the 3' untranslated region of the dopamine transporter locus | Genesis | 2006 | 255 |
| Rodent BDNF genes, novel promoters, novel splice variants, and regulation by cocaine | Brain Research | 2006 | 251 |
| Increased occupancy of dopamine receptors in human striatum during cue-elicited cocaine craving | Neuropsychopharmacology | 2006 | 244 |
| Ethics. Incidental findings in brain imaging research | Science | 2006 | 201 |
| Pattern of impaired working memory during major depression | Journal of Affective Disorders | 2006 | 200 |
| Activation of group II metabotropic glutamate receptors in the nucleus accumbens shell attenuates context-induced relapse to heroin seeking | Neuropsychopharmacology | 2006 | 192 |
| The infant development, environment, and lifestyle study: effects of prenatal methamphetamine exposure, polydrug exposure, and poverty on intrauterine growth | Pediatrics | 2006 | 190 |
| Cooperative transcription activation by Nurr1 and Pitx3 induces embryonic stem cell maturation to the midbrain dopamine neuron phenotype | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 184 |
| Neuroanatomical dissociation between bottom-up and top-down processes of visuospatial selective attention | NeuroImage | 2006 | 180 |
| Anandamide administration alone and after inhibition of fatty acid amide hydrolase (FAAH) increases dopamine levels in the nucleus accumbens shell in rats | Journal of Neurochemistry | 2006 | 163 |
| Projecting drug use among aging baby boomers in 2020 | Annals of Epidemiology | 2006 | 154 |
| Methamphetamine and other substance use during pregnancy: preliminary estimates from the Infant Development, Environment, and Lifestyle (IDEAL) study | Maternal and Child Health Journal | 2006 | 152 |
| Primary reinforcing effects of nicotine are triggered from multiple regions both inside and outside the ventral tegmental area | Journal of Neuroscience | 2006 | 148 |
| Two brain sites for cannabinoid reward | Journal of Neuroscience | 2006 | 147 |
