| # | Title | Journal | Year | Citations |
|---|
| 1 | The Fatigue Severity Scale | Archives of Neurology | 1989 | 4,899 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 3 | Estimates of the prevalence of arthritis and other rheumatic conditions in the United States: Part II | Arthritis and Rheumatism | 2008 | 4,029 |
| 4 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 5 | Interpreting the Clinical Importance of Treatment Outcomes in Chronic Pain Clinical Trials: IMMPACT Recommendations | Journal of Pain | 2008 | 2,564 |
| 6 | Estimates of the prevalence of arthritis and selected musculoskeletal disorders in the United States | Arthritis and Rheumatism | 1998 | 2,294 |
| 7 | Estimates of the prevalence of arthritis and other rheumatic conditions in the United States: Part I | Arthritis and Rheumatism | 2008 | 1,918 |
| 8 | A census of human RNA-binding proteins | Nature Reviews Genetics | 2014 | 1,671 |
| 9 | The sympathetic nerve--an integrative interface between two supersystems: the brain and the immune system | Pharmacological Reviews | 2000 | 1,513 |
| 10 | Cohesin Loss Eliminates All Loop Domains | Cell | 2017 | 1,454 |
| 11 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 12 | A Missense Single-Nucleotide Polymorphism in a Gene Encoding a Protein Tyrosine Phosphatase (PTPN22) Is Associated with Rheumatoid Arthritis | American Journal of Human Genetics | 2004 | 1,313 |
| 13 | mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants | Nature | 2021 | 1,232 |
| 14 | Mechanisms Underlying Lineage Commitment and Plasticity of Helper CD4 + T Cells | Science | 2010 | 1,151 |
| 15 | Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci | Nature Genetics | 2010 | 1,132 |
| 16 | 2019 European League Against Rheumatism/American College of Rheumatology Classification Criteria for Systemic Lupus Erythematosus | Arthritis and Rheumatology | 2019 | 1,098 |
| 17 | Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease | Nature Medicine | 2016 | 1,088 |
| 18 | Impaired TH17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome | Nature | 2008 | 1,046 |
| 19 | Janus kinases in immune cell signaling | Immunological Reviews | 2009 | 982 |
| 20 | Modulatory Effects of 1,25-Dihydroxyvitamin D3 on Human B Cell Differentiation | Journal of Immunology | 2007 | 936 |
| 21 | JAK and STAT Signaling Molecules in Immunoregulation and Immune-Mediated Disease | Immunity | 2012 | 933 |
| 22 | The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17–producing effector T helper cells in vivo | Nature Immunology | 2009 | 921 |
| 23 | STAT4and the Risk of Rheumatoid Arthritis and Systemic Lupus Erythematosus | New England Journal of Medicine | 2007 | 914 |
| 24 | An Autoinflammatory Disease with Deficiency of the Interleukin-1–Receptor Antagonist | New England Journal of Medicine | 2009 | 892 |
| 25 | The shortened disabilities of the arm, shoulder and hand questionnaire (Quick DASH): validity and reliability based on responses within the full-length DASH | BMC Musculoskeletal Disorders | 2006 | 778 |
| 26 | JAK inhibition as a therapeutic strategy for immune and inflammatory diseases | Nature Reviews Drug Discovery | 2017 | 759 |
| 27 | 2019 European League Against Rheumatism/American College of Rheumatology classification criteria for systemic lupus erythematosus | Annals of the Rheumatic Diseases | 2019 | 759 |
| 28 | Clinical manifestations in 105 persons with nevoid basal cell carcinoma syndrome | | 1997 | 753 |
| 29 | Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS) | Journal of Experimental Medicine | 2011 | 749 |
| 30 | JAKs and STATs in Immunity, Immunodeficiency, and Cancer | New England Journal of Medicine | 2013 | 738 |
| 31 | De novoCIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): A new member of the expanding family of pyrin-associated autoinflammatory diseases | Arthritis and Rheumatism | 2002 | 727 |
| 32 | EULAR recommendations for the management of antiphospholipid syndrome in adults | Annals of the Rheumatic Diseases | 2019 | 664 |
| 33 | Lymphoid tissue inducer–like cells are an innate source of IL-17 and IL-22 | Journal of Experimental Medicine | 2009 | 653 |
| 34 | T-bet is rapidly induced by interferon- in lymphoid and myeloid cells | Proceedings of the National Academy of Sciences of the United States of America | 2001 | 648 |
| 35 | Systemic lupus erythematosus: an autoimmune disease of B cell hyperactivity | Nature Immunology | 2001 | 637 |
| 36 | Diverse Targets of the Transcription Factor STAT3 Contribute to T Cell Pathogenicity and Homeostasis | Immunity | 2010 | 605 |
| 37 | Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease | Nature Genetics | 2010 | 595 |
| 38 | Regulation of B Cell Differentiation and Plasma Cell Generation by IL-21, a Novel Inducer of Blimp-1 and Bcl-6 | Journal of Immunology | 2004 | 588 |
| 39 | An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome | Nature Genetics | 2014 | 585 |
| 40 | IL-21 Induces Differentiation of Human Naive and Memory B Cells into Antibody-Secreting Plasma Cells | Journal of Immunology | 2005 | 580 |
| 41 | Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 580 |
| 42 | The alliance of sphingosine-1-phosphate and its receptors in immunity | Nature Reviews Immunology | 2008 | 570 |
| 43 | Modulation of Innate and Adaptive Immune Responses by Tofacitinib (CP-690,550) | Journal of Immunology | 2011 | 569 |
| 44 | Constitutively activated Jak-STAT pathway in T cells transformed with HTLV-I | Science | 1995 | 562 |
| 45 | Cytokines and autoimmunity | Nature Reviews Immunology | 2002 | 558 |
| 46 | IL-21 Is Produced by Th17 Cells and Drives IL-17 Production in a STAT3-dependent Manner | Journal of Biological Chemistry | 2007 | 549 |
| 47 | A short course of BG9588 (anti-CD40 ligand antibody) improves serologic activity and decreases hematuria in patients with proliferative lupus glomerulonephritis | Arthritis and Rheumatism | 2003 | 546 |
| 48 | Sir2 Regulates Skeletal Muscle Differentiation as a Potential Sensor of the Redox State | Molecular Cell | 2003 | 542 |
| 49 | The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation | Genes and Development | 2004 | 534 |
| 50 | Complete structure and expression in transfected cells of high affinity IgE receptor | Nature | 1989 | 524 |
