| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Proposed minimum reporting standards for chemical analysis | Metabolomics | 2007 | 3,589 |
| 3 | The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements | Nature Biotechnology | 2006 | 1,927 |
| 4 | Biodegradation of polycyclic aromatic hydrocarbons | Biodegradation | 1992 | 1,529 |
| 5 | Mechanisms of nanotoxicity: Generation of reactive oxygen species | Journal of Food and Drug Analysis | 2014 | 1,061 |
| 6 | Cytotoxicity Effects of Graphene and Single-Wall Carbon Nanotubes in Neural Phaeochromocytoma-Derived PC12 Cells | ACS Nano | 2010 | 1,025 |
| 7 | The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models | Nature Biotechnology | 2010 | 795 |
| 8 | Distribution of methyl and ethyl adducts following alkylation with monofunctional alkylating agents | Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis | 1990 | 779 |
| 9 | A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence | Nature Medicine | 2015 | 753 |
| 10 | The Estrogen Receptor Relative Binding Affinities of 188 Natural and Xenochemicals: Structural Diversity of Ligands | Toxicological Sciences | 2000 | 689 |
| 11 | Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation | EMBO Journal | 2011 | 655 |
| 12 | Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines. | Proceedings of the National Academy of Sciences of the United States of America | 1989 | 599 |
| 13 | Toxicity and Environmental Risks of Nanomaterials: Challenges and Future Needs | Journal of Environmental Science and Health, Part C: Environmental Carcinogenesis and Ecotoxicology Reviews | 2009 | 593 |
| 14 | Growth Curves and Survival Characteristics of the Animals Used in the Biomarkers of Aging Program | Journals of Gerontology - Series A Biological Sciences and Medical Sciences | 1999 | 587 |
| 15 | Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin | Molecular Cancer Therapeutics | 2008 | 580 |
| 16 | Downregulation of miR-122 in the rodent and human hepatocellular carcinomas | Journal of Cellular Biochemistry | 2006 | 575 |
| 17 | Rapid Identification of Intact Whole Bacteria Based on Spectral Patterns using Matrix-assisted Laser Desorption/Ionization with Time-of-flight Mass Spectrometry | Rapid Communications in Mass Spectrometry | 1996 | 559 |
| 18 | Ketamine-Induced Neuronal Cell Death in the Perinatal Rhesus Monkey | Toxicological Sciences | 2007 | 559 |
| 19 | Evaluation of DNA microarray results with quantitative gene expression platforms | Nature Biotechnology | 2006 | 558 |
| 20 | Metal‐based nanoparticles and their toxicity assessment | Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology | 2010 | 542 |
| 21 | Ketamine anesthesia during the first week of life can cause long-lasting cognitive deficits in rhesus monkeys | Neurotoxicology and Teratology | 2011 | 516 |
| 22 | Pyrrolizidine Alkaloids—Genotoxicity, Metabolism Enzymes, Metabolic Activation, and Mechanisms | Drug Metabolism Reviews | 2004 | 511 |
| 23 | Biodegradation of polycyclic aromatic hydrocarbons | Current Opinion in Biotechnology | 1993 | 510 |
| 24 | Principles and pitfalls in the analysis of prenatal treatment effects in multiparous species | Neurotoxicology and Teratology | 1992 | 484 |
| 25 | The Reduction of Azo Dyes by the Intestinal Microflora | Critical Reviews in Microbiology | 1992 | 465 |
| 26 | MALDI-TOF mass spectrometry of bacteria | Mass Spectrometry Reviews | 2001 | 463 |
| 27 | Carbon Nanotubes as Plant Growth Regulators: Effects on Tomato Growth, Reproductive System, and Soil Microbial Community | Small | 2013 | 444 |
| 28 | Performance comparison of one-color and two-color platforms within the Microarray Quality Control (MAQC) project | Nature Biotechnology | 2006 | 440 |
| 29 | Neomorphic agouti mutations in obese yellow mice | Nature Genetics | 1994 | 434 |
| 30 | Metallic-based micro and nanocomposites in food contact materials and active food packaging | Trends in Food Science and Technology | 2012 | 424 |
| 31 | Moderate Folate Depletion Increases Plasma Homocysteine and Decreases Lymphocyte DNA Methylation in Postmenopausal Women | Journal of Nutrition | 1998 | 423 |
| 32 | The concordance between RNA-seq and microarray data depends on chemical treatment and transcript abundance | Nature Biotechnology | 2014 | 420 |
| 33 | Microbial Metabolism of Polycyclic Aromatic Hydrocarbons | Advances in Applied Microbiology | 1984 | 418 |
| 34 | Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolites | Pharmacogenetics and Genomics | 1992 | 411 |
| 35 | The Role of Glutathione and Glutathione Transferases in Chemical Cardnogenesi | Critical Reviews in Biochemistry and Molecular Biology | 1990 | 410 |
| 36 | PCR detection and quantitation of predominant anaerobic bacteria in human and animal fecal samples | Applied and Environmental Microbiology | 1996 | 405 |
| 37 | An Evaluation of the Biological and Toxicological Properties ofAloe Barbadensis(Miller), Aloe Vera | Journal of Environmental Science and Health, Part C: Environmental Carcinogenesis and Ecotoxicology Reviews | 2006 | 398 |
| 38 | Rat toxicogenomic study reveals analytical consistency across microarray platforms | Nature Biotechnology | 2006 | 389 |
| 39 | Mutagenicity of azo dyes: Structure-activity relationships | Mutation Research - Reviews in Genetic Toxicology | 1992 | 387 |
| 40 | SARS-like WIV1-CoV poised for human emergence | Proceedings of the National Academy of Sciences of the United States of America | 2016 | 373 |
| 41 | Malachite Green: A Toxicological Review | Journal of the American College of Toxicology | 1996 | 370 |
| 42 | Toward interoperable bioscience data | Nature Genetics | 2012 | 362 |
| 43 | Proposed minimum reporting standards for data analysis in metabolomics | Metabolomics | 2007 | 361 |
| 44 | A comprehensive quantitative analysis of methylated and ethylated DNA using high pressure liquid chromatography | Carcinogenesis | 1980 | 359 |
| 45 | Assessment of the toxic potential of graphene family nanomaterials | Journal of Food and Drug Analysis | 2014 | 359 |
| 46 | Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire | Proceedings of the National Academy of Sciences of the United States of America | 2012 | 354 |
| 47 | Expression of genes related to oxidative stress in the mouse brain after exposure to silver-25 nanoparticles☆ | Toxicology Letters | 2009 | 351 |
| 48 | Population Dynamics of Salmonella enterica Serotypes in Commercial Egg and Poultry Production | Applied and Environmental Microbiology | 2011 | 347 |
| 49 | Toxicology and genetic toxicology in the new era of “toxicogenomics”: impact of “-omics” technologies | Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis | 2002 | 344 |
| 50 | Fixation of Testes and Eyes Using a Modified Davidson's Fluid: Comparison with Bouin's Fluid and Conventional Davidson's Fluid | Toxicologic Pathology | 2002 | 337 |
