| # | Title | Journal | Year | Citations |
|---|
| 1 | Lifetime Prevalence of Mental Disorders in U.S. Adolescents: Results from the National Comorbidity Survey Replication–Adolescent Supplement (NCS-A) | Journal of the American Academy of Child and Adolescent Psychiatry | 2010 | 4,750 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 3 | Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease | Nature Genetics | 2013 | 3,741 |
| 4 | Arterial and Cardiac Aging: Major Shareholders in Cardiovascular Disease Enterprises | Circulation | 2003 | 1,925 |
| 5 | Sigma-1 Receptor Chaperones at the ER- Mitochondrion Interface Regulate Ca2+ Signaling and Cell Survival | Cell | 2007 | 1,474 |
| 6 | Reactive Oxygen Species (Ros-Induced) Ros Release | Journal of Experimental Medicine | 2000 | 1,263 |
| 7 | Prevalence and Correlates of Eating Disorders in Adolescents | Archives of General Psychiatry | 2011 | 1,252 |
| 8 | Service Utilization for Lifetime Mental Disorders in U.S. Adolescents: Results of the National Comorbidity Survey–Adolescent Supplement (NCS-A) | Journal of the American Academy of Child and Adolescent Psychiatry | 2011 | 1,192 |
| 9 | Organization of the stress system and its dysregulation in melancholic and atypical depression: high vs low CRH/NE states | Molecular Psychiatry | 2002 | 1,121 |
| 10 | Genome-wide association study identifies eight loci associated with blood pressure | Nature Genetics | 2009 | 1,104 |
| 11 | Aggression in humans correlates with cerebrospinal fluid amine metabolites | Psychiatry Research | 1979 | 1,077 |
| 12 | Arterial and Cardiac Aging: Major Shareholders in Cardiovascular Disease Enterprises | Circulation | 2003 | 1,057 |
| 13 | Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits | Nature Genetics | 2018 | 924 |
| 14 | Arterial and Cardiac Aging: Major Shareholders in Cardiovascular Disease Enterprises | Circulation | 2003 | 886 |
| 15 | Effects of Intermittent Fasting on Health, Aging, and Disease | New England Journal of Medicine | 2019 | 864 |
| 16 | Glycogen synthase kinase-3β mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore | Journal of Clinical Investigation | 2004 | 854 |
| 17 | Major Depression in the National Comorbidity Survey–Adolescent Supplement: Prevalence, Correlates, and Treatment | Journal of the American Academy of Child and Adolescent Psychiatry | 2015 | 836 |
| 18 | Common genetic variants influence human subcortical brain structures | Nature | 2015 | 772 |
| 19 | A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance | Nature Genetics | 2012 | 762 |
| 20 | Arterial stiffness, pressure and flow pulsatility and brain structure and function: the Age, Gene/Environment Susceptibility – Reykjavik Study | Brain | 2011 | 713 |
| 21 | Identification of preclinical Alzheimer's disease by a profile of pathogenic proteins in neurally derived blood exosomes: A case‐control study | Alzheimer's and Dementia | 2015 | 656 |
| 22 | MAM: more than just a housekeeper | Trends in Cell Biology | 2009 | 654 |
| 23 | Identification of common variants associated with human hippocampal and intracranial volumes | Nature Genetics | 2012 | 594 |
| 24 | Excessive Loss of Skeletal Muscle Mass in Older Adults With Type 2 Diabetes | Diabetes Care | 2009 | 593 |
| 25 | Reduced Striatal Dopamine Transporter Density in Abstinent Methamphetamine and Methcathinone Users: Evidence from Positron Emission Tomography Studies with [11C]WIN-35,428 | Journal of Neuroscience | 1998 | 570 |
| 26 | Evidence for a differential role of HPA-axis function, inflammation and metabolic syndrome in melancholic versus atypical depression | Molecular Psychiatry | 2013 | 551 |
| 27 | A Drug Burden Index to Define the Functional Burden of Medications in Older People | Archives of Internal Medicine | 2007 | 548 |
| 28 | Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche | Nature | 2014 | 548 |
| 29 | Rare and low-frequency coding variants alter human adult height | Nature | 2017 | 544 |
| 30 | Evidence for Abnormal Cortical Functional Connectivity During Working Memory in Schizophrenia | American Journal of Psychiatry | 2001 | 537 |
| 31 | Aging-Associated Cardiovascular Changes and Their Relationship to Heart Failure | Heart Failure Clinics | 2012 | 523 |
| 32 | Meta-analysis of the acute effects of nicotine and smoking on human performance | Psychopharmacology | 2010 | 521 |
| 33 | Methamphetamine toxicity and messengers of death | Brain Research Reviews | 2009 | 519 |
| 34 | G Protein–Coupled Receptor Oligomerization Revisited: Functional and Pharmacological Perspectives | Pharmacological Reviews | 2014 | 497 |
| 35 | GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 483 |
| 36 | Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer's disease | Neurobiology of Disease | 2007 | 474 |
| 37 | Invited Review Free radicals and the pathobiology of brain dopamine systems | Neurochemistry International | 1998 | 469 |
| 38 | The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies | Brain Research Reviews | 2009 | 463 |
| 39 | A relationship between serotonin transporter genotype and in vivo protein expression and alcohol neurotoxicity | Biological Psychiatry | 2000 | 452 |
| 40 | The genetic architecture of the human cerebral cortex | Science | 2020 | 450 |
| 41 | Factors modulating neural reactivity to drug cues in addiction: A survey of human neuroimaging studies | Neuroscience and Biobehavioral Reviews | 2014 | 438 |
| 42 | Cardiovascular Features of Heart Failure With Preserved Ejection Fraction Versus Nonfailing Hypertensive Left Ventricular Hypertrophy in the Urban Baltimore Community | Journal of the American College of Cardiology | 2007 | 425 |
| 43 | Resting state functional connectivity in addiction: Lessons learned and a road ahead | NeuroImage | 2012 | 421 |
| 44 | Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 Individuals | PLoS Genetics | 2012 | 419 |
| 45 | Transplanted adrenal chromaffin cells in rat brain reduce lesion-induced rotational behaviour | Nature | 1981 | 417 |
| 46 | Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function | Nature Communications | 2016 | 412 |
| 47 | Synchronized delta oscillations correlate with the resting-state functional MRI signal | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 409 |
| 48 | Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure | Nature Genetics | 2011 | 403 |
| 49 | Targeting the murine serotonin transporter: insights into human neurobiology | Nature Reviews Neuroscience | 2008 | 402 |
| 50 | Adenosine A2A-Dopamine D2 Receptor-Receptor Heteromerization | Journal of Biological Chemistry | 2003 | 401 |
