| # | Title | Journal | Year | Citations |
|---|
| 1 | The Revised Classification of Eukaryotes | Journal of Eukaryotic Microbiology | 2012 | 1,340 |
| 2 | Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms | Nature | 1999 | 1,317 |
| 3 | Defective haematopoiesis in fetal liver resulting from inactivation of the EKLF gene | Nature | 1995 | 531 |
| 4 | Transcription complex stability and chromatin dynamics in vivo | Nature | 1995 | 469 |
| 5 | A temperature-sensitive disorder in basal transcription and DNA repair in humans | Nature Genetics | 2001 | 362 |
| 6 | Photic Induction of mPer1 and mPer2 in Cry-Deficient Mice Lacking a Biological Clock | Science | 1999 | 348 |
| 7 | Use of metabolically competent human hepatoma cells for the detection of mutagens and antimutagens | Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis | 1998 | 346 |
| 8 | Measurement of internal body time by blood metabolomics | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 246 |
| 9 | Nucleocytoplasmic shuttling and mCRY-dependent inhibition of ubiquitylation of the mPER2 clock protein | EMBO Journal | 2002 | 236 |
| 10 | RAD26, the functional S. cerevisiae homolog of the Cockayne syndrome B gene ERCC6. | EMBO Journal | 1994 | 224 |
| 11 | A mouse model for the cystic fibrosis delta F508 mutation. | EMBO Journal | 1995 | 213 |
| 12 | Use of human hepatoma cells for in vitro metabolic activation of chemical mutagens/carcinogens | Mutagenesis | 1991 | 173 |
| 13 | Frequencies of X-ray-induced Chromosome Translocations in Human Peripheral Lymphocytes as Detected byin SituHybridization Using Chromosome-specific DNA Libraries | International Journal of Radiation Biology | 1992 | 168 |
| 14 | The octamer binding factor Oct6: cDNA cloning and expression in early embryonic cells | Nucleic Acids Research | 1990 | 133 |
| 15 | The Drosophila brahma complex is an essential coactivator for the trithorax group protein zeste | Genes and Development | 2000 | 131 |
| 16 | Characterization of the human lysosomal α-glucosidase gene | Biochemical Journal | 1990 | 127 |
| 17 | Cell type-specific hypersensitivity to oxidative damage in CSB and XPA mice | DNA Repair | 2003 | 125 |
| 18 | The XRCC genes: expanding roles in DNA double-strand break repair | DNA Repair | 2004 | 118 |
| 19 | Fragile X-Related Proteins Regulate Mammalian Circadian Behavioral Rhythms | American Journal of Human Genetics | 2008 | 109 |
| 20 | The BMAL1 C terminus regulates the circadian transcription feedback loop | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 106 |
| 21 | Chromosomal aberrations in peripheral blood lymphocytes from native Andean women and children from Northwestern Argentina exposed to arsenic in drinking water | Mutation Research - Genetic Toxicology Testing and Biomonitoring of Environmental Or Occupational Exposure | 1996 | 99 |
| 22 | Phase Responses to Light Pulses in Mice Lacking Functional per or cry Genes | Journal of Biological Rhythms | 2004 | 97 |
| 23 | View of a mouse clock gene ticking | Nature | 2001 | 91 |
| 24 | Different Effects of CSA and CSB Deficiency on Sensitivity to Oxidative DNA Damage | Molecular and Cellular Biology | 2004 | 90 |
| 25 | Functional Evolution of the Photolyase/Cryptochrome Protein Family: Importance of the C Terminus of Mammalian CRY1 for Circadian Core Oscillator Performance | Molecular and Cellular Biology | 2006 | 90 |
| 26 | Discrimination between complete and incomplete chromosome exchanges in X-irradiated human lymphocytes using FISH with pan-centromeric and chromosome specific DNA probes in combination with telomeric PNA probe | International Journal of Radiation Biology | 2000 | 89 |
| 27 | Lifespan of human lymphocytes estimated during a six year cytogenetic follow-up of individuals accidentally exposed in the 1987 radiological accident in Brazil | Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis | 1995 | 82 |
| 28 | Elongated Telomeres inscidMice | Genomics | 1999 | 81 |
| 29 | Homologous recombination in the fission yeast Schizosaccharomyces pombe: different requirements for the rhp51 + , rhp54 + and rad22 + genes | Current Genetics | 1997 | 80 |
| 30 | Detection of incomplete exchanges and interstitial fragments in X-irradiated human lymphocytes using a telomeric PNA probe | International Journal of Radiation Biology | 1998 | 80 |
| 31 | Enhanced repair of cyclobutane pyrimidine dimers and improved UV resistance in photolyase transgenic mice | EMBO Journal | 2002 | 80 |
| 32 | Structure and expression of the excision repair geneERCC6, involved in the human disorder Cockayne's syndrome group B | Nucleic Acids Research | 1993 | 79 |
| 33 | Xeroderma pigmentosum complementation group H falls into complementation group D | Mutation Research DNA Repair | 1991 | 74 |
| 34 | Review of clinical, cytogenetic, and molecular aspects of Ph-negative CML | Cancer Genetics and Cytogenetics | 1991 | 73 |
| 35 | Cloning, Tissue Expression, and Mapping of a Human Photolyase Homolog with Similarity to Plant Blue-Light Receptors | Genomics | 1996 | 73 |
| 36 | Detection of chromosomal aberrations by fluorescence in situ hybridization in the first three postirradiation divisions of human lymphocytes | Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis | 1996 | 71 |
| 37 | Altered food-anticipatory activity rhythm in Cryptochrome-deficient mice | Neuroscience Research | 2005 | 71 |
| 38 | Light Entrainment of the Mammalian Circadian Clock by a PRKCA-Dependent Posttranslational Mechanism | Neuron | 2007 | 71 |
| 39 | Transcription-coupled repair removes both cyclobutane pyrimidine dimers and 6-4 photoproducts with equal efficiency and in a sequential way from transcribed DNA in xeroderma pigmentosum group C fibroblasts | EMBO Journal | 1995 | 71 |
| 40 | Biomonitoring of occupational exposure to styrene in a plastics lamination plant | Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis | 1999 | 70 |
| 41 | The Drosophila melanogaster RAD54 Homolog, DmRAD54, Is Involved in the Repair of Radiation Damage and Recombination | Molecular and Cellular Biology | 1997 | 69 |
| 42 | The use of fluorescence in situ hybridization for the detection of aneugens in cytokinesis-blocked mouse splenocytes | Mutagenesis | 1993 | 66 |
| 43 | Radiation-induced chromosomal breakage and rejoining in interphase-metaphase chromosomes of human lymphocytes | Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis | 1991 | 63 |
| 44 | Kinetics of the formation of chromosome aberrations in X-irradiated human lymphocytes, using PCC and FISH | Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis | 1998 | 62 |
| 45 | The level of the tissue‐specific factor GATA‐1 affects the cell‐cycle machinery | Genes and Function | 1997 | 61 |
| 46 | Analysis of radiation-induced chromosomal aberrations using telomeric and centromeric PNA probes | International Journal of Radiation Biology | 2000 | 61 |
| 47 | Cell-type-specific consequences of nucleotide excision repair deficiencies: Embryonic stem cells versus fibroblasts | DNA Repair | 2008 | 60 |
| 48 | Detection of aneugenic and clastogenic potential of X-rays, directly and indirectly acting chemicals in human hepatoma (Hep G2) and peripheral blood lymphocytes, using the micronucleus assay and fluorescent in situ hybridization with a DNA centromeric probe | Mutagenesis | 1996 | 59 |
| 49 | Human papillomavirus mediated inhibition of DNA damage sensing and repair drives skin carcinogenesis | Molecular Cancer | 2015 | 56 |
| 50 | XR-C1, a new CHO cell mutant which is defective in DNA-PKcs, is impaired in both V(D)J coding and signal joint formation | Nucleic Acids Research | 1998 | 54 |
