| # | Title | Journal | Year | Citations |
|---|
| 1 | Surviving Sepsis Campaign | Critical Care Medicine | 2013 | 6,362 |
| 2 | 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference | Critical Care Medicine | 2003 | 5,266 |
| 3 | Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock, 2012 | Intensive Care Medicine | 2013 | 3,906 |
| 4 | 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference | Intensive Care Medicine | 2003 | 1,965 |
| 5 | High-Dose Antithrombin III in Severe Sepsis | JAMA - Journal of the American Medical Association | 2001 | 1,240 |
| 6 | A phase II study of temozolomide vs. procarbazine in patients with glioblastoma multiforme at first relapse | British Journal of Cancer | 2000 | 1,154 |
| 7 | Practice Guidelines for the Management of Infectious Diarrhea | Clinical Infectious Diseases | 2001 | 927 |
| 8 | Calcium plus Vitamin D Supplementation and the Risk of Colorectal Cancer | New England Journal of Medicine | 2006 | 907 |
| 9 | Patients’ use of the internet for medical information | Journal of General Internal Medicine | 2002 | 783 |
| 10 | Effect of Eritoran, an Antagonist of MD2-TLR4, on Mortality in Patients With Severe Sepsis | JAMA - Journal of the American Medical Association | 2013 | 625 |
| 11 | HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials | Lancet, The | 2015 | 562 |
| 12 | Erythropoietin receptor mRNA expression in human endothelial cells. | Proceedings of the National Academy of Sciences of the United States of America | 1994 | 541 |
| 13 | Social Marketing and Public Health Intervention | Health Education Quarterly | 1988 | 522 |
| 14 | Balance and Strength Training in Older Adults: Intervention Gains and Tai Chi Maintenance | Journal of the American Geriatrics Society | 1996 | 403 |
| 15 | Lactate Measurements in Sepsis-Induced Tissue Hypoperfusion | Critical Care Medicine | 2015 | 367 |
| 16 | Treatment effects of high-dose antithrombin without concomitant heparin in patients with severe sepsis with or without disseminated intravascular coagulation | Journal of Thrombosis and Haemostasis | 2006 | 363 |
| 17 | The development of brain white matter microstructure | NeuroImage | 2018 | 363 |
| 18 | Dysfunction of the Diaphragm | New England Journal of Medicine | 2012 | 355 |
| 19 | The roles of the myofibroblast in idiopathic pulmonary fibrosis. Ultrastructural and immunohistochemical features of sites of active extracellular matrix synthesis | American Journal of Pathology | 1991 | 338 |
| 20 | Risk of functional decline among well elders | Journal of Clinical Epidemiology | 1989 | 331 |
| 21 | Ultrasound evaluation of the paralyzed diaphragm. | American Journal of Respiratory and Critical Care Medicine | 1997 | 286 |
| 22 | Long-term adjustment of survivors of early-stage breast carcinoma, 20 years after adjuvant chemotherapy | Cancer | 2003 | 274 |
| 23 | The Pawtucket Heart Health Program: community changes in cardiovascular risk factors and projected disease risk. | American Journal of Public Health | 1995 | 270 |
| 24 | Atypical antipsychotics in the treatment of drug-induced psychosis in Parkinson's disease | Movement Disorders | 2000 | 247 |
| 25 | Longitudinal outcome of Parkinson’s disease patients with psychosis | Neurology | 2003 | 242 |
| 26 | A double-blind crossover study in moderately hypercholesterolemic men that compared the effect of aged garlic extract and placebo administration on blood lipids | American Journal of Clinical Nutrition | 1996 | 237 |
| 27 | Risk of Cardiovascular Disease by Hysterectomy Status, With and Without Oophorectomy | Circulation | 2005 | 224 |
| 28 | Quetiapine for the treatment of drug-induced psychosis in Parkinson's disease | Movement Disorders | 1999 | 220 |
| 29 | Diaphragm thickening during inspiration | Journal of Applied Physiology | 1997 | 208 |
| 30 | Endotoxins and Other Sepsis Triggers | Contributions To Nephrology | 2010 | 208 |
| 31 | Hyperhomocysteinemia in Chronic Renal Disease | Journal of the American Society of Nephrology: JASN | 1999 | 208 |
| 32 | Diagnosis, management, and survival of patients with leptomeningeal cancer based on cerebrospinal fluid-flow status | Cancer | 1995 | 200 |
| 33 | Strategies for Optimizing Adherence to Highly Active Antiretroviral Therapy: Lessons from Research and Clinical Practice | Clinical Infectious Diseases | 2001 | 191 |
| 34 | Clinical aspects and cytokine response in severe H1N1 influenza A virus infection | Critical Care | 2010 | 186 |
| 35 | A dynamic posturography study of balance in healthy elderly | Neurology | 1992 | 186 |
| 36 | Survival of patients with marginal zone lymphoma | Cancer | 2013 | 181 |
| 37 | Hyperhomocysteinemia and traditional cardiovascular disease risk factors in end-stage renal disease patients on dialysis: a case-control study | Atherosclerosis | 1995 | 173 |
| 38 | The emergin role of clozapine in the treatment of movement disorders | Movement Disorders | 1997 | 164 |
| 39 | Proprotein Convertases in Health and Disease | New England Journal of Medicine | 2011 | 162 |
| 40 | Inhibition of the RAGE products increases survival in experimental models of severe sepsis and systemic infection | Critical Care | 2007 | 140 |
| 41 | Early nutrition influences developmental myelination and cognition in infants and young children | NeuroImage | 2018 | 136 |
| 42 | Efficacy of a Monoclonal Antibody Directed against Tumor Necrosis Factor in Protecting Neutropenic Rats from Lethal Infection with Pseudomonas aeruginosa | Journal of Infectious Diseases | 1990 | 132 |
| 43 | Flock Worker's Lung: Chronic Interstitial Lung Disease in the Nylon Flocking Industry | Annals of Internal Medicine | 1998 | 132 |
| 44 | Correlates of Postmenopausal Estrogen Use and Trends through the 1980s in Two Southeastern New England Communities | American Journal of Epidemiology | 1993 | 130 |
| 45 | Clozapine for the treatment of drug-induced psychosis in Parkinson's disease: Results of the 12 week open label extension in the PSYCLOPS trial | Movement Disorders | 2001 | 125 |
| 46 | Neuropsychological and behavioral correlates of obstructive sleep apnea syndrome in children: A preliminary study | Sleep and Breathing | 2000 | 124 |
| 47 | Social isolation, C-reactive protein, and coronary heart disease mortality among community-dwelling adults | Social Science and Medicine | 2011 | 124 |
| 48 | 10 Altered Sensory Function and Balance in Older Persons | Journal of Gerontology | 1993 | 122 |
| 49 | Punding onL-dopa | Movement Disorders | 1999 | 121 |
| 50 | Driving and Dementia: A Review of the Literature | Journal of Geriatric Psychiatry and Neurology | 2004 | 120 |
