| Prospective Validation of a 21-Gene Expression Assay in Breast Cancer | New England Journal of Medicine | 2015 | 865 |
| Brentuximab vedotin as consolidation therapy after autologous stem-cell transplantation in patients with Hodgkin's lymphoma at risk of relapse or progression (AETHERA): a randomised, double-blind, placebo-controlled, phase 3 trial | Lancet, The | 2015 | 462 |
| The Epidemiology of Cirrhosis in the United States: A Population-based Study | Journal of Clinical Gastroenterology | 2015 | 413 |
| Randomized Phase Ib/II Study of Gemcitabine Plus Placebo or Vismodegib, a Hedgehog Pathway Inhibitor, in Patients With Metastatic Pancreatic Cancer | Journal of Clinical Oncology | 2015 | 323 |
| Diagnosis of monoclonal gammopathy of renal significance | Kidney International | 2015 | 261 |
| A Cluster Randomized Trial of Interventions to Improve Work Conditions and Clinician Burnout in Primary Care: Results from the Healthy Work Place (HWP) Study | Journal of General Internal Medicine | 2015 | 207 |
| Durable remissions in a pivotal phase 2 study of brentuximab vedotin in relapsed or refractory Hodgkin lymphoma | Blood | 2015 | 176 |
| Oral prenylation inhibition with lonafarnib in chronic hepatitis D infection: a proof-of-concept randomised, double-blind, placebo-controlled phase 2A trial | Lancet Infectious Diseases, The | 2015 | 158 |
| Type III open tibia fractures: immediate antibiotic prophylaxis minimizes infection | Journal of Orthopaedic Trauma | 2015 | 141 |
| Osteopontin mediates an MZF1-TGF-β1-dependent transformation of mesenchymal stem cells into cancer-associated fibroblasts in breast cancer | Oncogene | 2015 | 124 |
| Thyroid storm: an updated review | Journal of Intensive Care Medicine | 2015 | 122 |
| Subclinical atherosclerosis measures for cardiovascular prediction in CKD | Journal of the American Society of Nephrology: JASN | 2015 | 81 |
| Correlation of scar localization between cardiac magnetic resonance imaging and electro-anatomic mapping at electrophysiology study in patients with cardiac rhythm management devices | Journal of Cardiovascular Magnetic Resonance | 2015 | 78 |
| Point-Counterpoint: Large Multiplex PCR Panels Should Be First-Line Tests for Detection of Respiratory and Intestinal Pathogens | Journal of Clinical Microbiology | 2015 | 76 |
| MRI Assessment of Ablation-Induced Scarring in Atrial Fibrillation: Analysis from the DECAAF Study | Journal of Cardiovascular Electrophysiology | 2015 | 68 |
| The Neoadjuvant Model Is Still the Future for Drug Development in Breast Cancer | Clinical Cancer Research | 2015 | 67 |
| Prevalence of suspected nonalcoholic fatty liver disease in Hispanic/Latino individuals differs by heritage | Clinical Gastroenterology and Hepatology | 2015 | 62 |
| Quality indicators for the management of Barrett's esophagus, dysplasia, and esophageal adenocarcinoma: international consensus recommendations from the American Gastroenterological Association Symposium | Gastroenterology | 2015 | 61 |
| Percutaneous alternative to the Maze procedure for the treatment of persistent or long-standing persistent atrial fibrillation (aMAZE trial): Rationale and design | American Heart Journal | 2015 | 59 |
| Activation of hypoxia signaling induces phenotypic transformation of glioma cells: implications for bevacizumab antiangiogenic therapy | Oncotarget | 2015 | 58 |
| Change in health-related quality of life from before to after destination therapy mechanical circulatory support is similar for older and younger patients: analyses from INTERMACS | Journal of Heart and Lung Transplantation | 2015 | 55 |
| Gray zone lymphoma with features intermediate between classical Hodgkin lymphoma and diffuse large B-cell lymphoma: characteristics, outcomes, and prognostication among a large multicenter cohort | American Journal of Hematology | 2015 | 53 |
| Magnesium and Dialysis: The Neglected Cation | American Journal of Kidney Diseases | 2015 | 50 |
| New drugs of abuse | Pharmacotherapy | 2015 | 50 |
| Overexpression and knockout of miR-126 both promote leukemogenesis | Blood | 2015 | 50 |
