| # | Title | Journal | Year | Citations |
|---|
| 1 | Hybrid Monte Carlo | Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics | 1987 | 2,634 |
| 2 | DNA methylation landscapes: provocative insights from epigenomics | Nature Reviews Genetics | 2008 | 2,619 |
| 3 | Synthetic Molecular Motors and Mechanical Machines | Angewandte Chemie - International Edition | 2007 | 2,428 |
| 4 | Carbon capture and storage update | Energy and Environmental Science | 2014 | 1,765 |
| 5 | Changing potency by spontaneous fusion | Nature | 2002 | 1,452 |
| 6 | A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome | Nature Genetics | 2001 | 1,401 |
| 7 | The Genome of the Kinetoplastid Parasite, Leishmania major | Science | 2005 | 1,237 |
| 8 | Embryo-Derived Stem Cells: Of Mice and Men | Annual Review of Cell and Developmental Biology | 2001 | 1,150 |
| 9 | MadGraph/MadEvent v4: the new web generation | Journal of High Energy Physics | 2007 | 965 |
| 10 | Impacts of Atmospheric Anthropogenic Nitrogen on the Open Ocean | Science | 2008 | 964 |
| 11 | Unidirectional rotation in a mechanically interlocked molecular rotor | Nature | 2003 | 862 |
| 12 | The HadGEM2-ES implementation of CMIP5 centennial simulations | Geoscientific Model Development | 2011 | 803 |
| 13 | Xyloglucan endotransglycosylase, a new wall-loosening enzyme activity from plants | Biochemical Journal | 1992 | 790 |
| 14 | MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex | Nature Genetics | 1999 | 783 |
| 15 | Strategies and Tactics for the Metal‐Directed Synthesis of Rotaxanes, Knots, Catenanes, and Higher Order Links | Angewandte Chemie - International Edition | 2011 | 614 |
| 16 | A molecular information ratchet | Nature | 2007 | 602 |
| 17 | The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites | Nature | 1999 | 576 |
| 18 | Active metal template synthesis of rotaxanes, catenanes and molecular shuttles | Chemical Society Reviews | 2009 | 573 |
| 19 | A Reversible Synthetic Rotary Molecular Motor | Science | 2004 | 564 |
| 20 | Oxidative scission of plant cell wall polysaccharides by ascorbate-induced hydroxyl radicals | Biochemical Journal | 1998 | 512 |
| 21 | Creation and Manipulation of Three-Dimensional Optically Trapped Structures | Science | 2002 | 481 |
| 22 | Sensitivity and specificity of inferring genetic regulatory interactions from microarray experiments with dynamic Bayesian networks | Bioinformatics | 2003 | 461 |
| 23 | The biology of restriction and anti-restriction | Current Opinion in Microbiology | 2005 | 457 |
| 24 | Closely related proteins MBD2 and MBD3 play distinctive but interacting roles in mouse development | Genes and Development | 2001 | 453 |
| 25 | Description and validation of an array model — MAESTRO | Agricultural and Forest Meteorology | 1990 | 426 |
| 26 | Codon usage in the G+C-rich Streptomyces genome | Gene | 1992 | 417 |
| 27 | Early Palaeozoic orogenesis along the Indian margin of Gondwana: Tectonic response to Gondwana assembly | Earth and Planetary Science Letters | 2007 | 417 |
| 28 | Drying and wetting of Mediterranean soils stimulates decomposition and carbon dioxide emission: the "Birch effect" | Tree Physiology | 2007 | 415 |
| 29 | A two-step serum-free culture system supports development of human oocytes from primordial follicles in the presence of activin | Human Reproduction | 2008 | 410 |
| 30 | Cover Picture: Light‐Driven Transport of a Molecular Walker in Either Direction along a Molecular Track (Angew. Chem. Int. Ed. 1/2011) | Angewandte Chemie - International Edition | 2011 | 404 |
| 31 | The application of CuAAC ‘click’ chemistry to catenane and rotaxane synthesis | Chemical Society Reviews | 2010 | 400 |
| 32 | The Population Biology of Oak Gall Wasps (Hymenoptera: Cynipidae) | Annual Review of Entomology | 2002 | 398 |
| 33 | Drought sensitivity of Amazonian carbon balance revealed by atmospheric measurements | Nature | 2014 | 398 |
| 34 | Interactions between Ultrafine Particles and Transition Metals in Vivo and in Vitro | Toxicology and Applied Pharmacology | 2002 | 389 |
| 35 | P450 BM3: the very model of a modern flavocytochrome | Trends in Biochemical Sciences | 2002 | 385 |
| 36 | A synthetic molecular pentafoil knot | Nature Chemistry | 2012 | 379 |
| 37 | Constraints to growth of boreal forests | Nature | 2000 | 378 |
| 38 | Fire suppression by water sprays | Progress in Energy and Combustion Science | 2000 | 375 |
| 39 | Nitric oxide function in plant abiotic stress | Plant, Cell and Environment | 2017 | 360 |
| 40 | Catalytic “Click” Rotaxanes: A Substoichiometric Metal-Template Pathway to Mechanically Interlocked Architectures | Journal of the American Chemical Society | 2006 | 350 |
| 41 | What is individual quality? An evolutionary perspective | Trends in Ecology and Evolution | 2010 | 348 |
| 42 | Vigorous exchange between the Indian and Atlantic oceans at the end of the past five glacial periods | Nature | 2004 | 342 |
| 43 | An Unlockable–Relockable Iron Cage by Subcomponent Self‐Assembly | Angewandte Chemie - International Edition | 2008 | 323 |
| 44 | Improved Bounds for Mixing Rates of Markov Chains and Multicommodity Flow | Combinatorics Probability and Computing | 1992 | 320 |
| 45 | A synthetic small molecule that can walk down a track | Nature Chemistry | 2010 | 308 |
| 46 | Application of infrared thermography to the non-destructive testing of concrete and masonry bridges | NDT and E International | 2003 | 307 |
| 47 | Neurofascins Are Required to Establish Axonal Domains for Saltatory Conduction | Neuron | 2005 | 306 |
| 48 | Functional gene screening in embryonic stem cells implicates Wnt antagonism in neural differentiation | Nature Biotechnology | 2002 | 303 |
| 49 | Orientation dependence in fluorescent energy transfer between Cy3 and Cy5 terminally attached to double-stranded nucleic acids | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 301 |
| 50 | The ecological significance of long-distance water transport: short-term regulation, long-term acclimation and the hydraulic costs of stature across plant life forms | Plant, Cell and Environment | 2003 | 296 |
