| # | Title | Journal | Year | Citations |
|---|
| 1 | Stereotactic ablative radiotherapy versus standard of care palliative treatment in patients with oligometastatic cancers (SABR-COMET): a randomised, phase 2, open-label trial | Lancet, The | 2019 | 1,333 |
| 2 | The physics, biophysics and technology of photodynamic therapy | Physics in Medicine and Biology | 2008 | 849 |
| 3 | Olaparib combined with chemotherapy for recurrent platinum-sensitive ovarian cancer: a randomised phase 2 trial | Lancet Oncology, The | 2015 | 491 |
| 4 | Tecemotide (L-BLP25) versus placebo after chemoradiotherapy for stage III non-small-cell lung cancer (START): a randomised, double-blind, phase 3 trial | Lancet Oncology, The | 2014 | 446 |
| 5 | The expanding role of primary care in cancer control | Lancet Oncology, The | 2015 | 399 |
| 6 | Radiation Therapy and Tamoxifen: Concurrent or Sequential? That Is the Question | Journal of Clinical Oncology | 2005 | 321 |
| 7 | Continuing education meetings and workshops: effects on professional practice and health care outcomes | | 2001 | 262 |
| 8 | Safety and efficacy results of the advanced renal cell carcinoma sorafenib expanded access program in North America | Cancer | 2010 | 240 |
| 9 | Self-management education interventions for patients with cancer: a systematic review | Supportive Care in Cancer | 2017 | 182 |
| 10 | Palliative thoracic radiotherapy in lung cancer: An American Society for Radiation Oncology evidence-based clinical practice guideline | Practical Radiation Oncology | 2011 | 174 |
| 11 | Chemoradiotherapy with or without panitumumab in patients with unresected, locally advanced squamous-cell carcinoma of the head and neck (CONCERT-1): a randomised, controlled, open-label phase 2 trial | Lancet Oncology, The | 2015 | 161 |
| 12 | Participant selection for lung cancer screening by risk modelling (the Pan-Canadian Early Detection of Lung Cancer [PanCan] study): a single-arm, prospective study | Lancet Oncology, The | 2017 | 158 |
| 13 | Cultural influences on the physician–patient encounter: The case of shared treatment decision-making | Patient Education and Counseling | 2006 | 136 |
| 14 | Myxoid\Round Cell Liposarcoma (MRCLS) Revisited: An Analysis of 418 Primarily Managed Cases | Annals of Surgical Oncology | 2012 | 121 |
| 15 | Canadian consensus guidelines for the management of testicular germ cell cancer | Canadian Urological Association Journal | 2013 | 119 |
| 16 | A phase II study of sunitinib in patients with recurrent epithelial ovarian and primary peritoneal carcinoma: an NCIC Clinical Trials Group Study | Annals of Oncology | 2011 | 117 |
| 17 | Parental Knowledge, Attitudes, and Behaviours towards Human Papillomavirus Vaccination for Their Children: A Systematic Review from 2001 to 2011 | Obstetrics and Gynecology International | 2012 | 115 |
| 18 | Pre-treatment risk stratification of prostate cancer patients: A critical review | Canadian Urological Association Journal | 2012 | 115 |
| 19 | What implementation interventions increase cancer screening rates? a systematic review | Implementation Science | 2011 | 113 |
| 20 | Phase III, randomized trial of mirvetuximab soravtansine versus chemotherapy in patients with platinum-resistant ovarian cancer: primary analysis of FORWARD I | Annals of Oncology | 2021 | 105 |
| 21 | Metabolic flexibility determines human NK cell functional fate in the tumor microenvironment | Cell Metabolism | 2021 | 104 |
| 22 | Radiotherapy fractionation for the palliation of uncomplicated painful bone metastases – an evidence-based practice guideline | BMC Cancer | 2004 | 103 |
| 23 | A Systematic Review and Meta-Analysis of Oncologic Outcomes of Pre- Versus Postoperative Radiation in Localized Resectable Soft-Tissue Sarcoma | Annals of Surgical Oncology | 2010 | 100 |
| 24 | Testing personalized medicine: patient and physician expectations of next-generation genomic sequencing in late-stage cancer care | European Journal of Human Genetics | 2014 | 98 |
| 25 | An Optimized Clinical Regimen for the Oncolytic Virus PV701 | Clinical Cancer Research | 2007 | 94 |
| 26 | Comparison of Toxicity Associated With Early Morning Versus Late Afternoon Radiotherapy in Patients With Head-and-Neck Cancer: A Prospective Randomized Trial of the National Cancer Institute of Canada Clinical Trials Group (HN3) | International Journal of Radiation Oncology Biology Physics | 2009 | 90 |
| 27 | Influence of hospital characteristics on operative death and survival of patients after major cancer surgery in Ontario | Canadian Journal of Surgery | 2006 | 89 |
| 28 | Surgical Margins and Handling of Soft-Tissue Sarcoma in Extremities: A Clinical Practice Guideline | Current Oncology | 2013 | 88 |
| 29 | A systematic review of information in decision aids | Health Expectations | 2007 | 76 |
| 30 | Feasibility of real time next generation sequencing of cancer genes linked to drug response: Results from a clinical trial | International Journal of Cancer | 2013 | 76 |
| 31 | A phase I dose-escalation study of apatorsen (OGX-427), an antisense inhibitor targeting heat shock protein 27 (Hsp27), in patients with castration-resistant prostate cancer and other advanced cancers | Annals of Oncology | 2016 | 74 |
| 32 | Resveratrol enhances prostate cancer cell response to ionizing radiation. Modulation of the AMPK, Akt and mTOR pathways | Radiation Oncology | 2011 | 73 |
| 33 | A Pan-Canadian practice guideline: prevention, screening, assessment, and treatment of sleep disturbances in adults with cancer | Supportive Care in Cancer | 2013 | 72 |
| 34 | Postoperative Adjuvant Systemic Therapy in Completely Resected Non–Small-Cell Lung Cancer: A Systematic Review | Clinical Lung Cancer | 2017 | 70 |
| 35 | Ten years results of the Canadian breast intensity modulated radiation therapy (IMRT) randomized controlled trial | Radiotherapy and Oncology | 2016 | 68 |
| 36 | Guideline for optimization of colorectal cancer surgery and pathology | Journal of Surgical Oncology | 2010 | 67 |
| 37 | NSCLC, metastatic CheckMate 026: A phase 3 trial of nivolumab vs investigator's choice (IC) of platinum-based doublet chemotherapy (PT-DC) as first-line therapy for stage iv/recurrent programmed death ligand 1 (PD-L1)−positive NSCLC | Annals of Oncology | 2016 | 66 |
| 38 | A phase II study of single-agent RO4929097, a gamma-secretase inhibitor of Notch signaling, in patients with recurrent platinum-resistant epithelial ovarian cancer: A study of the Princess Margaret, Chicago and California phase II consortia | Gynecologic Oncology | 2015 | 65 |
| 39 | Custirsen (OGX-011) combined with cabazitaxel and prednisone versus cabazitaxel and prednisone alone in patients with metastatic castration-resistant prostate cancer previously treated with docetaxel (AFFINITY): a randomised, open-label, international, phase 3 trial | Lancet Oncology, The | 2017 | 65 |
| 40 | A dynamic model for ALA-PDT of skin: simulation of temporal and spatial distributions of ground-state oxygen, photosensitizer and singlet oxygen | Physics in Medicine and Biology | 2010 | 64 |
| 41 | Nivolumab (anti-PD-1; BMS-936558, ONO-4538) and ipilimumab in first-line NSCLC: Interim phase I results. | Journal of Clinical Oncology | 2014 | 64 |
| 42 | A phase 2 study of cediranib in recurrent or persistent ovarian, peritoneal or fallopian tube cancer: A trial of the Princess Margaret, Chicago and California Phase II Consortia | Gynecologic Oncology | 2015 | 62 |
| 43 | Phase 1/2 Study of the CD56-Targeting Antibody-Drug Conjugate Lorvotuzumab Mertansine (IMGN901) in Combination With Carboplatin/Etoposide in Small-Cell Lung Cancer Patients With Extensive-Stage Disease | Clinical Lung Cancer | 2017 | 59 |
| 44 | Effective interventions to facilitate the uptake of breast, cervical and colorectal cancer screening: an implementation guideline | Implementation Science | 2011 | 57 |
| 45 | Carboplatin and pegylated liposomal doxorubicin versus carboplatin and paclitaxel in partially platinum-sensitive ovarian cancer patients: results from a subset analysis of the CALYPSO phase III trial | Annals of Oncology | 2012 | 57 |
| 46 | Brachytherapy Improves Biochemical Failure–Free Survival in Low- and Intermediate-Risk Prostate Cancer Compared With Conventionally Fractionated External Beam Radiation Therapy: A Propensity Score Matched Analysis | International Journal of Radiation Oncology Biology Physics | 2015 | 57 |
| 47 | Guidelines on the Use of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy in Patients with Peritoneal Surface Malignancy Arising from Colorectal or Appendiceal Neoplasms | Current Oncology | 2015 | 54 |
| 48 | Checkpoint inhibitors in patients with metastatic renal cell carcinoma: Results from the International Metastatic Renal Cell Carcinoma Database Consortium | Cancer | 2018 | 53 |
| 49 | Phase I clinical, pharmacokinetic and pharmacodynamic study of SB939, an oral histone deacetylase (HDAC) inhibitor, in patients with advanced solid tumours | British Journal of Cancer | 2011 | 52 |
| 50 | Olaparib plus paclitaxel plus carboplatin (P/C) followed by olaparib maintenance treatment in patients (pts) with platinum-sensitive recurrent serous ovarian cancer (PSR SOC): A randomized, open-label phase II study. | Journal of Clinical Oncology | 2012 | 50 |
