| # | Title | Journal | Year | Citations |
|---|
| 1 | Sequence and organization of the human mitochondrial genome | Nature | 1981 | 8,950 |
| 2 | THE CHEMOTACTIC EFFECT OF MIXTURES OF ANTIBODY AND ANTIGEN ON POLYMORPHONUCLEAR LEUCOCYTES | Journal of Experimental Medicine | 1962 | 2,644 |
| 3 | Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system | Nature | 1974 | 1,965 |
| 4 | Nucleotide sequence of bacteriophage φX174 DNA | Nature | 1977 | 1,862 |
| 5 | De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-κB signalling | Nature | 2004 | 1,691 |
| 6 | CELLULAR RESISTANCE TO INFECTION | Journal of Experimental Medicine | 1962 | 1,524 |
| 7 | The C-type lectin-like domain superfamily | FEBS Journal | 2005 | 1,162 |
| 8 | The Transcriptional Repressor Bcl-6 Directs T Follicular Helper Cell Lineage Commitment | Immunity | 2009 | 1,041 |
| 9 | A Double-Negative Feedback Loop between ZEB1-SIP1 and the microRNA-200 Family Regulates Epithelial-Mesenchymal Transition | Cancer Research | 2008 | 956 |
| 10 | Follicular Helper T Cells | Annual Review of Immunology | 2016 | 912 |
| 11 | Establishment of Four Strains of Cells from Insect Tissues Grown in vitro | Nature | 1962 | 882 |
| 12 | Immunohistochemical localization of macrophages and microglia in the adult and developing mouse brain | Neuroscience | 1985 | 855 |
| 13 | A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity | Nature | 2005 | 777 |
| 14 | Aire regulates negative selection of organ-specific T cells | Nature Immunology | 2003 | 729 |
| 15 | Kinetics of the reversible inhibition of enzyme-catalysed reactions by tight-binding inhibitors | Biochimica Et Biophysica Acta - Biomembranes | 1969 | 722 |
| 16 | ACTN3 Genotype Is Associated with Human Elite Athletic Performance | American Journal of Human Genetics | 2003 | 708 |
| 17 | Diversity and Dynamics of Dendritic Signaling | Science | 2000 | 700 |
| 18 | Action potential initiation and backpropagation in neurons of the mammalian CNS | Trends in Neurosciences | 1997 | 671 |
| 19 | Enhanced immunological surveillance in mice heterozygous at the H-2 gene complex | Nature | 1975 | 663 |
| 20 | Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences | Nature | 2007 | 661 |
| 21 | Deficiency of Th17 cells in hyper IgE syndrome due to mutations in STAT3 | Journal of Experimental Medicine | 2008 | 610 |
| 22 | Dark adaptation and the retinoid cycle of vision | Progress in Retinal and Eye Research | 2004 | 602 |
| 23 | Aberrant Mucin Assembly in Mice Causes Endoplasmic Reticulum Stress and Spontaneous Inflammation Resembling Ulcerative Colitis | PLoS Medicine | 2008 | 602 |
| 24 | Action potential generation requires a high sodium channel density in the axon initial segment | Nature Neuroscience | 2008 | 592 |
| 25 | Cellular and genetic mechanisms of self tolerance and autoimmunity | Nature | 2005 | 586 |
| 26 | Combining docking and molecular dynamic simulations in drug design | Medicinal Research Reviews | 2006 | 586 |
| 27 | Multiple Associated Proteins Regulate Proteasome Structure and Function | Molecular Cell | 2002 | 579 |
| 28 | Genetic Recombination in Pseudomonas aeruginosa | Microbiology (United Kingdom) | 1955 | 576 |
| 29 | Transfer of specific cytotoxic T lymphocytes protects mice inoculated with influenza virus | Nature | 1978 | 569 |
| 30 | Follicular B helper T cells in antibody responses and autoimmunity | Nature Reviews Immunology | 2005 | 541 |
| 31 | Quantal analysis of synaptic potentials in neurons of the central nervous system. | Physiological Reviews | 1990 | 532 |
| 32 | Two levels of protection for the B cell genome during somatic hypermutation | Nature | 2008 | 524 |
| 33 | A Clinical Grading Scale to Predict Malignant Hyperthermia Susceptibility | Anesthesiology | 1994 | 520 |
| 34 | An autocrine TGF-β/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition | Molecular Biology of the Cell | 2011 | 505 |
| 35 | Zeta, a novel class of glutathione transferases in a range of species from plants to humans | Biochemical Journal | 1997 | 501 |
| 36 | Cloning of mammalian heparanase, an important enzyme in tumor invasion and metastasis | Nature Medicine | 1999 | 501 |
| 37 | A NEW ANALYSIS OF ALLOGENEIC INTERACTIONS | The Australian Journal of Experimental Biology and Medical Science | 1975 | 497 |
| 38 | Molecular cloning of cDNA for murine interleukin-3 | Nature | 1984 | 496 |
| 39 | Dietary Fiber and Bacterial SCFA Enhance Oral Tolerance and Protect against Food Allergy through Diverse Cellular Pathways | Cell Reports | 2016 | 489 |
| 40 | DNA repair is limiting for haematopoietic stem cells during ageing | Nature | 2007 | 475 |
| 41 | The Behavior and Significance of Slow-Binding Enzyme Inhibitors | Advances in Enzymology and Related Areas of Molecular Biology | 2006 | 473 |
| 42 | Nuclear targeting signal recognition: a key control point in nuclear transport? | BioEssays | 2000 | 472 |
| 43 | Crystalline Dihydropteroylglutamic Acid | Nature | 1960 | 469 |
| 44 | Determinants of Voltage Attenuation in Neocortical Pyramidal Neuron Dendrites | Journal of Neuroscience | 1998 | 456 |
| 45 | Channels underlying neuronal calcium-activated potassium currents | Progress in Neurobiology | 2002 | 452 |
| 46 | The role of heparan sulphate in inflammation | Nature Reviews Immunology | 2006 | 433 |
| 47 | A BIOLOGICAL ROLE FOR THE MAJOR HISTOCOMPATIBILITY ANTIGENS | Lancet, The | 1975 | 430 |
| 48 | High frequencies of α-thalassaemia are the result of natural selection by malaria | Nature | 1986 | 412 |
| 49 | Regulation of protein transport to the nucleus: central role of phosphorylation | Physiological Reviews | 1996 | 405 |
| 50 | Axon Initial Segment Kv1 Channels Control Axonal Action Potential Waveform and Synaptic Efficacy | Neuron | 2007 | 396 |
