| # | Title | Journal | Year | Citations |
|---|
| 1 | Bayesian measures of model complexity and fit | Journal of the Royal Statistical Society Series B: Statistical Methodology | 2002 | 9,644 |
| 2 | WinBUGS - A Bayesian modelling framework: Concepts, structure, and extensibility | Statistics and Computing | 2000 | 4,470 |
| 3 | Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase | Nature Medicine | 2002 | 3,692 |
| 4 | Approximate Bayesian Computation in Population Genetics | Genetics | 2002 | 2,220 |
| 5 | Pre-eclampsia and risk of cardiovascular disease and cancer in later life: systematic review and meta-analysis | BMJ: British Medical Journal | 2007 | 2,046 |
| 6 | Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression | Nature | 1998 | 1,943 |
| 7 | Ghrelin Enhances Appetite and Increases Food Intake in Humans | Journal of Clinical Endocrinology and Metabolism | 2001 | 1,866 |
| 8 | Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase | Nature | 2002 | 1,823 |
| 9 | The SCARE Statement: Consensus-based surgical case report guidelines | International Journal of Surgery | 2016 | 1,585 |
| 10 | Measurement of clinical and subclinical tumour response using [18F]-fluorodeoxyglucose and positron emission tomography: review and 1999 EORTC recommendations | European Journal of Cancer | 1999 | 1,550 |
| 11 | Explaining heterogeneity in meta-analysis: a comparison of methods | European Journal of Cancer | 1999 | 1,478 |
| 12 | Diagnostic criteria for hereditary hemorrhagic telangiectasia (Rendu-Osler-Weber syndrome) | European Journal of Cancer | 2000 | 1,391 |
| 13 | The Novel Hypothalamic Peptide Ghrelin Stimulates Food Intake and Growth Hormone Secretion | Endocrinology | 2000 | 1,370 |
| 14 | Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies | Nature Genetics | 1998 | 1,361 |
| 15 | STROCSS 2019 Guideline: Strengthening the reporting of cohort studies in surgery | International Journal of Surgery | 2019 | 1,248 |
| 16 | Mutations in the gene encoding lamin A/C cause autosomal dominant Emery-Dreifuss muscular dystrophy | Nature Genetics | 1999 | 1,245 |
| 17 | Identification of mesenchymal stem/progenitor cells in human first-trimester fetal blood, liver, and bone marrow | Blood | 2001 | 1,235 |
| 18 | What do we mean by validating a prognostic model? | Blood | 2000 | 1,216 |
| 19 | Increased Production of Immature Myeloid Cells in Cancer Patients: A Mechanism of Immunosuppression in Cancer | Journal of Immunology | 2001 | 1,214 |
| 20 | Chromatin signatures of pluripotent cell lines | Nature Cell Biology | 2006 | 1,213 |
| 21 | ANTI-TNFα THERAPY OFRHEUMATOIDARTHRITIS: What Have We Learned? | Annual Review of Immunology | 2001 | 1,207 |
| 22 | Chronic Obstructive Pulmonary Disease | New England Journal of Medicine | 2000 | 1,189 |
| 23 | Chronic obstructive pulmonary disease: molecular and cellularmechanisms | European Respiratory Journal | 2003 | 1,174 |
| 24 | Ghrelin Causes Hyperphagia and Obesity in Rats | Diabetes | 2001 | 993 |
| 25 | The use of fractional polynomials to model continuous risk variables in epidemiology | International Journal of Epidemiology | 1999 | 966 |
| 26 | Hepatocytes from non-hepatic adult stem cells | Nature | 2000 | 931 |
| 27 | Chemical, pharmacokinetic and pharmacodynamic properties of statins: an update | Fundamental and Clinical Pharmacology | 2005 | 920 |
| 28 | Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas | Nature Genetics | 2013 | 851 |
| 29 | UKPDS 50: Risk factors for incidence and progression of retinopathy in Type II diabetes over 6 years from diagnosis | Diabetologia | 2001 | 840 |
| 30 | Phosphatidylinositol 3-Kinase/AKT-mediated Activation of Estrogen Receptor α | Journal of Biological Chemistry | 2001 | 831 |
| 31 | Expression of Cd34 and Myf5 Defines the Majority of Quiescent Adult Skeletal Muscle Satellite Cells | Journal of Cell Biology | 2000 | 795 |
| 32 | Endotoxin and immune activation in chronic heart failure: a prospective cohort study | Lancet, The | 1999 | 788 |
| 33 | Mice deficient in tumor necrosis factor-α are resistant to skin carcinogenesis | Nature Medicine | 1999 | 777 |
| 34 | Microvascular Permeability | Physiological Reviews | 1999 | 773 |
| 35 | Albumin: Biochemical properties and therapeutic potential | Hepatology | 2005 | 768 |
| 36 | Thymic Stromal Lymphopoietin Expression Is Increased in Asthmatic Airways and Correlates with Expression of Th2-Attracting Chemokines and Disease Severity | Journal of Immunology | 2005 | 759 |
| 37 | Thrombophilia in pregnancy: a systematic review | British Journal of Haematology | 2006 | 743 |
| 38 | Association of Transcriptionally Silent Genes with Ikaros Complexes at Centromeric Heterochromatin | Cell | 1997 | 724 |
| 39 | Systematic review of involving patients in the planning and development of health care | BMJ: British Medical Journal | 2002 | 717 |
| 40 | Analysis Of Htlv-I Proviral Load In 202 Ham/Tsp Patients And 243 Asymptomatic Htlv-I Carriers: High Proviral Load Strongly Predisposes To Ham/Tsp | Journal of NeuroVirology | 1998 | 711 |
| 41 | Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia | Current Biology | 2000 | 707 |
| 42 | A Hierarchical Role for Classical Pathway Complement Proteins in the Clearance of Apoptotic Cells in Vivo | Journal of Experimental Medicine | 2000 | 696 |
| 43 | Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats | Nature Genetics | 1999 | 692 |
| 44 | Influence of vitamin D deficiency and vitamin D receptor polymorphisms on tuberculosis among Gujarati Asians in west London: a case-control study | Lancet, The | 2000 | 691 |
| 45 | A modified silver staining protocol for visualization of proteins compatible with matrix-assisted laser desorption/ionization and electrospray ionization- mass spectrometry | Electrophoresis | 2000 | 682 |
| 46 | Subnuclear Compartmentalization of Immunoglobulin Loci During Lymphocyte Development | Science | 2002 | 671 |
| 47 | Hormonal Changes and Catabolic/Anabolic Imbalance in Chronic Heart Failure and Their Importance for Cardiac Cachexia | Circulation | 1997 | 671 |
| 48 | Maintaining internal representations: the role of the human superior parietal lobe | Nature Neuroscience | 1998 | 670 |
| 49 | Silver I: its antibacterial properties and mechanism of action | Journal of Wound Care | 2002 | 669 |
| 50 | Dopamine release from nigral transplants visualized in vivo in a Parkinson's patient | Nature Neuroscience | 1999 | 663 |
