| # | Title | Journal | Year | Citations |
|---|
| 1 | Impact of BAL Data on the Therapy and Outcome of Ventilator-Associated Pneumonia | Chest | 1997 | 940 |
| 2 | Risk Factors for Extubation Failure in Patients Following a Successful Spontaneous Breathing Trial | Chest | 2006 | 885 |
| 3 | A comparative study of the anti-inflammatory, anticoagulant, antiangiogenic, and antiadhesive activities of nine different fucoidans from brown seaweeds | Glycobiology | 2007 | 844 |
| 4 | Resolution of ventilator-associated pneumonia: Prospective evaluation of the clinical pulmonary infection score as an early clinical predictor of outcome* | Critical Care Medicine | 2003 | 802 |
| 5 | International ERS/ESICM/ESCMID/ALAT guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumonia | European Respiratory Journal | 2017 | 792 |
| 6 | Diagnosis and treatment of acute appendicitis: 2020 update of the WSES Jerusalem guidelines | World Journal of Emergency Surgery | 2020 | 533 |
| 7 | Targeted inhibition of galectin-1 gene expression in tumor cells results in heightened T cell-mediated rejection | Cancer Cell | 2004 | 497 |
| 8 | Galectins and their ligands: amplifiers, silencers or tuners of the inflammatory response? | Trends in Immunology | 2002 | 493 |
| 9 | 2019 WSES guidelines for the management of severe acute pancreatitis | World Journal of Emergency Surgery | 2019 | 444 |
| 10 | An International Prospective Study of Pneumococcal Bacteremia: Correlation with In Vitro Resistance, Antibiotics Administered, and Clinical Outcome | Clinical Infectious Diseases | 2003 | 426 |
| 11 | Consensus Summary Statement of the International Multidisciplinary Consensus Conference on Multimodality Monitoring in Neurocritical Care | Neurocritical Care | 2014 | 339 |
| 12 | International myeloma working group consensus recommendations on imaging in monoclonal plasma cell disorders | Lancet Oncology, The | 2019 | 290 |
| 13 | Cesarean Section Rates and Maternal and Neonatal Mortality in Low-, Medium-, and High-Income Countries: An Ecological Study | Birth | 2006 | 283 |
| 14 | Azithromycin in addition to standard of care versus standard of care alone in the treatment of patients admitted to the hospital with severe COVID-19 in Brazil (COALITION II): a randomised clinical trial | Lancet, The | 2020 | 278 |
| 15 | Eearly loss of HIV-infected patients on potent antiretroviral therapy programmes in lower-income countries | Bulletin of the World Health Organization | 2008 | 275 |
| 16 | How much phenotypic variation can be attributed toparkingenotype? | Annals of Neurology | 2003 | 271 |
| 17 | Epidemiology of Candidemia in Latin America: A Laboratory-Based Survey | PLoS ONE | 2013 | 267 |
| 18 | Consensus summary statement of the International Multidisciplinary Consensus Conference on Multimodality Monitoring in Neurocritical Care | Intensive Care Medicine | 2014 | 258 |
| 19 | Gastrointestinal manifestations in Parkinson’s disease: prevalence and occurrence before motor symptoms | Journal of Neurology | 2013 | 247 |
| 20 | Network meta-analysis: a technique to gather evidence from direct and indirect comparisons | Pharmacy Practice | 2017 | 243 |
| 21 | Programmed Death (PD)-1:PD-Ligand 1/PD-Ligand 2 Pathway Inhibits T Cell Effector Functions during Human Tuberculosis | Journal of Immunology | 2008 | 234 |
| 22 | Appropriateness and delay to initiate therapy in ventilator-associated pneumonia | European Respiratory Journal | 2006 | 232 |
| 23 | Budesonide/Formoterol in a Single Inhaler for Maintenance and Relief in Mild-to-Moderate Asthma | Chest | 2006 | 228 |
| 24 | Incidence, risk factors and outcome of barotrauma in mechanically ventilated patients | Intensive Care Medicine | 2004 | 219 |
| 25 | Galectin-1 as a potential cancer target | British Journal of Cancer | 2005 | 203 |
| 26 | The diagnosis of manganese-induced parkinsonism | NeuroToxicology | 2006 | 203 |
| 27 | Role of galectins in inflammatory and immunomodulatory processes | Biochimica Et Biophysica Acta - General Subjects | 2002 | 202 |
| 28 | COVID-19 severity and mortality in patients with chronic lymphocytic leukemia: a joint study by ERIC, the European Research Initiative on CLL, and CLL Campus | Leukemia | 2020 | 198 |
| 29 | Apoptosis and expression of Bcl-2 and Bax in eutopic endometrium from women with endometriosis | Fertility and Sterility | 2000 | 187 |
| 30 | Galectin-1 Suppresses Autoimmune Retinal Disease by Promoting Concomitant Th2- and T Regulatory-Mediated Anti-Inflammatory Responses | Journal of Immunology | 2006 | 180 |
| 31 | Prevalence of cutaneous manifestations in 200 patients with eating disorders | International Journal of Dermatology | 2000 | 161 |
| 32 | The role of galectins in the initiation, amplification and resolution of the inflammatory response | Tissue Antigens | 2004 | 161 |
| 33 | A Prospective, Cross-sectional Survey Study of the Natural History of Niemann-Pick Disease Type B | Pediatrics | 2008 | 157 |
| 34 | Adjustable Suburethral Sling (Male Remeex System®) in the Treatment of Male Stress Urinary Incontinence: A Multicentric European Study | European Urology | 2007 | 155 |
| 35 | 2018 WSES/SIS-E consensus conference: recommendations for the management of skin and soft-tissue infections | World Journal of Emergency Surgery | 2018 | 154 |
| 36 | Community-Acquired Pneumonia | Chest | 2000 | 153 |
| 37 | Association of Serotypes of Streptococcus pneumoniae with Disease Severity and Outcome in Adults: An International Study | Clinical Infectious Diseases | 2007 | 153 |
| 38 | Mucopolysaccharidosis I, II, and VI: brief review and guidelines for treatment | Genetics and Molecular Biology | 2010 | 150 |
| 39 | American Society of Blood and Marrow Transplantation, European Society of Blood and Marrow Transplantation, Blood and Marrow Transplant Clinical Trials Network, and International Myeloma Working Group Consensus Conference on Salvage Hematopoietic Cell Transplantation in Patients with Relapsed Multiple Myeloma | Biology of Blood and Marrow Transplantation | 2015 | 146 |
| 40 | Neuropathological findings after bone marrow transplantation: an autopsy study of 180 cases | Bone Marrow Transplantation | 2000 | 142 |
| 41 | The potential use of biomarkers as an adjunctive tool for staging bipolar disorder | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2009 | 139 |
| 42 | Results of Unrelated Cord Blood Transplant in Fanconi Anemia Patients: Risk Factor Analysis for Engraftment and Survival | Biology of Blood and Marrow Transplantation | 2007 | 138 |
| 43 | Exploratory, Randomized, Double-blind, Placebo-controlled Study on the Effects of Bifidobacterium infantis Natren Life Start Strain Super Strain in Active Celiac Disease | Journal of Clinical Gastroenterology | 2013 | 135 |
| 44 | Long-Term Safety of In Utero Exposure to Anti-TNFα Drugs for the Treatment of Inflammatory Bowel Disease: Results from the Multicenter European TEDDY Study | American Journal of Gastroenterology | 2018 | 134 |
| 45 | Fusarium: more than a node or a foot-shaped basal cell | Studies in Mycology | 2021 | 134 |
| 46 | Randomized Trial of Near-infrared Incisionless Fluorescent Cholangiography | Annals of Surgery | 2019 | 128 |
| 47 | Treatment of Bolivian Mucosal Leishmaniasis with Miltefosine | Clinical Infectious Diseases | 2007 | 126 |
| 48 | Immunization with Recombinant Brucella Species Outer Membrane Protein Omp16 or Omp19 in Adjuvant Induces Specific CD4+ and CD8+ T Cells as Well as Systemic and Oral Protection against Brucella abortus Infection | Infection and Immunity | 2009 | 126 |
| 49 | Galectin-3 Mediates IL-4-Induced Survival and Differentiation of B Cells: Functional Cross-Talk and Implications during Trypanosoma cruzi Infection | Journal of Immunology | 2004 | 121 |
| 50 | Primary Immunodeficiency Diseases in Latin America: The Second Report of the LAGID Registry | Journal of Clinical Immunology | 2007 | 119 |
