| # | Title | Journal | Year | Citations |
|---|
| 1 | Comparison and Evaluation of Methods for Liver Segmentation From CT Datasets | IEEE Transactions on Medical Imaging | 2009 | 848 |
| 2 | An Ultrasonogram Reporting System for Thyroid Nodules Stratifying Cancer Risk for Clinical Management | Journal of Clinical Endocrinology and Metabolism | 2009 | 749 |
| 3 | Esophageal motility disorders on high‐resolution manometry: Chicago classification version 4.0© | Neurogastroenterology and Motility | 2021 | 468 |
| 4 | The diagnosis of male infertility: an analysis of the evidence to support the development of global WHO guidance—challenges and future research opportunities | Human Reproduction Update | 2017 | 320 |
| 5 | Successful Management of Benign Biliary Strictures With Fully Covered Self-Expanding Metal Stents | Gastroenterology | 2014 | 234 |
| 6 | Incidence, 30-day case-fatality rate, and prognosis of stroke in Iquique, Chile: a 2-year community-based prospective study (PISCIS project) | Lancet, The | 2005 | 204 |
| 7 | Adjuvant Chemotherapy for High Risk Upper Tract Urothelial Carcinoma: Results From the Upper Tract Urothelial Carcinoma Collaboration | Journal of Urology | 2009 | 200 |
| 8 | Pembrolizumab in Relapsed or Refractory Primary Mediastinal Large B-Cell Lymphoma | Journal of Clinical Oncology | 2019 | 195 |
| 9 | Global Retinoblastoma Presentation and Analysis by National Income Level | JAMA Oncology | 2020 | 192 |
| 10 | Stroke epidemiology, prevention, and management strategies at a regional level: Latin America and the Caribbean | Lancet Neurology, The | 2007 | 188 |
| 11 | Impact of Lymph Node Dissection on Cancer Specific Survival in Patients With Upper Tract Urothelial Carcinoma Treated With Radical Nephroureterectomy | Journal of Urology | 2009 | 186 |
| 12 | Intensive blood pressure reduction with intravenous thrombolysis therapy for acute ischaemic stroke (ENCHANTED): an international, randomised, open-label, blinded-endpoint, phase 3 trial | Lancet, The | 2019 | 178 |
| 13 | Comparison of Oncologic Outcomes for Open and Laparoscopic Nephroureterectomy: A Multi-Institutional Analysis of 1249 Cases | European Urology | 2009 | 161 |
| 14 | Tumour architecture is an independent predictor of outcomes after nephroureterectomy: a multi‐institutional analysis of 1363 patients | BJU International | 2009 | 160 |
| 15 | Rivaroxaban or aspirin for patent foramen ovale and embolic stroke of undetermined source: a prespecified subgroup analysis from the NAVIGATE ESUS trial | Lancet Neurology, The | 2018 | 146 |
| 16 | The Extent of Lymphadenectomy Seems to Be Associated with Better Survival in Patients with Nonmetastatic Upper-Tract Urothelial Carcinoma: How Many Lymph Nodes Should Be Removed? | European Urology | 2009 | 143 |
| 17 | Acute symptomatic seizures secondary to autoimmune encephalitis and autoimmune‐associated epilepsy: Conceptual definitions | Epilepsia | 2020 | 138 |
| 18 | Predictors of relapse and treatment outcomes in biopsy-proven giant cell arteritis: a retrospective cohort study | Rheumatology | 2016 | 131 |
| 19 | Heterozygous Truncating Variants in POMP Escape Nonsense-Mediated Decay and Cause a Unique Immune Dysregulatory Syndrome | American Journal of Human Genetics | 2018 | 128 |
| 20 | Dose–Volume Constraints to Reduce Rectal Side Effects From Prostate Radiotherapy: Evidence From MRC RT01 Trial ISRCTN 47772397 | International Journal of Radiation Oncology Biology Physics | 2010 | 123 |
| 21 | Mechanisms of Antibiotic Resistance | International Journal of Radiation Oncology Biology Physics | 0 | 122 |
| 22 | Risk stratification of patients with nodal involvement in upper tract urothelial carcinoma: value of lymph‐node density | BJU International | 2009 | 93 |
| 23 | Clinical spectrum of Kufor‐Rakeb syndrome in the Chilean kindred with ATP13A2 mutations | Movement Disorders | 2010 | 93 |
| 24 | Head Position and Cerebral Blood Flow Velocity in Acute Ischemic Stroke: A Systematic Review and Meta-Analysis | Cerebrovascular Diseases | 2014 | 88 |
| 25 | Evidence-based guidelines for the use of tracheostomy in critically ill patients | Journal of Critical Care | 2017 | 87 |
| 26 | Airway pressure release ventilation versus assist-control ventilation: a comparative propensity score and international cohort study | Intensive Care Medicine | 2010 | 86 |
| 27 | Rivaroxaban for secondary stroke prevention in patients with embolic strokes of undetermined source: Design of the NAVIGATE ESUS randomized trial | European Stroke Journal | 2016 | 83 |
| 28 | Rationale, Design, and Progress of the ENhanced Control of Hypertension ANd Thrombolysis Stroke Study (ENCHANTED) Trial: An International Multicenter 2 × 2 Quasi-Factorial Randomized Controlled Trial of Low- vs. Standard-Dose rt-PA and Early Intensive vs. Guideline-Recommended Blood Pressure Lowering in Patients with Acute Ischaemic Stroke Eligible for Thrombolysis Treatment | International Journal of Stroke | 2015 | 82 |
| 29 | Injury to the infrapatellar branch of the saphenous nerve in ACL reconstruction with the hamstrings technique: Clinical and electrophysiological study | Knee | 2008 | 77 |
| 30 | Outcomes of Flexible Ureterorenoscopy for Solitary Renal Stones in the CROES URS Global Study | Journal of Urology | 2015 | 75 |
| 31 | Autonomic disturbances in narcolepsy | Sleep Medicine Reviews | 2011 | 73 |
| 32 | Efficacy and Safety of Rivaroxaban Versus Aspirin in Embolic Stroke of Undetermined Source and Carotid Atherosclerosis | Stroke | 2019 | 72 |
| 33 | Liver transplantation for hepatocellular carcinoma: evaluation of the alpha‐fetoprotein model in a multicenter cohort from Latin America | Liver International | 2016 | 71 |
| 34 | Frequency of the Types of Alopecia at Twenty-Two Specialist Hair Clinics: A Multicenter Study | Skin Appendage Disorders | 2019 | 61 |
| 35 | Failure of High-Dose Daptomycin for Bacteremia Caused by Daptomycin-Susceptible Enterococcus faecium Harboring LiaSR Substitutions | Clinical Infectious Diseases | 2014 | 60 |
| 36 | A Non-Randomized Multicentre Trial of Human Immune Plasma for Treatment of Hantavirus Cardiopulmonary Syndrome Caused by Andes Virus | Antiviral Therapy | 2015 | 60 |
| 37 | Change in Cognition and Other Non-Motor Symptoms With Obstructive Sleep Apnea Treatment in Parkinson Disease | Journal of Clinical Sleep Medicine | 2018 | 60 |
| 38 | An Independent Interobserver Reliability and Intraobserver Reproducibility Evaluation of the New AOSpine Thoracolumbar Spine Injury Classification System | Spine | 2015 | 59 |
| 39 | Viable Pregnancy in a patient with metastatic melanoma treated with double checkpoint immunotherapy | Seminars in Oncology | 2018 | 58 |
| 40 | Accuracy of Transcranial Doppler Compared With CT Angiography in Diagnosing Arterial Obstructions in Acute Ischemic Strokes | Stroke | 2009 | 56 |
| 41 | Gallstones and gallbladder cancer-volume and weight of gallstones are associated with gallbladder cancer: A case-control study | Journal of Surgical Oncology | 2006 | 54 |
| 42 | Extracorporeal Membrane Oxygenation for COVID-19–associated Severe Acute Respiratory Distress Syndrome in Chile: A Nationwide Incidence and Cohort Study | American Journal of Respiratory and Critical Care Medicine | 2021 | 54 |
| 43 | Gallbladder Cancer in Chile | American Journal of Clinical Pathology | 2014 | 52 |
| 44 | Optimizing the Definitions of Stroke, Transient Ischemic Attack, and Infarction for Research and Application in Clinical Practice | Frontiers in Neurology | 2017 | 51 |
| 45 | Factors predictive of serious infections over time in systemic lupus erythematosus patients: data from a multi-ethnic, multi-national, Latin American lupus cohort | Lupus | 2019 | 51 |
| 46 | Pleural effusion complicates monitoring of respiratory mechanics* | Critical Care Medicine | 2011 | 50 |
| 47 | Misconceptions regarding the adequacy of best medical intervention alone for asymptomatic carotid stenosis | Journal of Vascular Surgery | 2020 | 50 |
| 48 | Validity of the NIHSS in predicting arterial occlusion in cerebral infarction is time-dependent | Neurology | 2011 | 49 |
| 49 | Residual defects of the external anal sphincter following primary repair: an observational study using transperineal ultrasound | Ultrasound in Obstetrics and Gynecology | 2014 | 48 |
| 50 | Diagnostic performance of endobronchial ultrasound‐guided mediastinal lymph node sampling in early stage non‐small cell lung cancer: A prospective study | Respirology | 2018 | 48 |
