| # | Title | Journal | Year | Citations |
|---|
| 1 | New perspectives in cell adhesion: RGD and integrins | Science | 1987 | 4,737 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 3 | Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule | Nature | 1984 | 3,513 |
| 4 | Phase III Study of Pemetrexed in Combination With Cisplatin Versus Cisplatin Alone in Patients With Malignant Pleural Mesothelioma | Journal of Clinical Oncology | 2003 | 2,796 |
| 5 | Improved Overall Survival in Melanoma with Combined Dabrafenib and Trametinib | New England Journal of Medicine | 2015 | 2,240 |
| 6 | Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo | Oncogene | 1994 | 1,667 |
| 7 | EAU Guidelines on Prostate Cancer. Part 1: Screening, Diagnosis, and Local Treatment with Curative Intent—Update 2013 | European Urology | 2014 | 1,613 |
| 8 | Negative regulation of transforming growth factor-β by the proteoglycan decorin | Nature | 1990 | 1,460 |
| 9 | Integrins. | Journal of Clinical Investigation | 1991 | 1,440 |
| 10 | EAU Guidelines on Prostate Cancer | European Urology | 2008 | 1,373 |
| 11 | Fibronectin and its Receptors | Annual Review of Biochemistry | 1988 | 1,339 |
| 12 | Radical nephrectomy plus interferon-alfa-based immunotherapy compared with interferon alfa alone in metastatic renal-cell carcinoma: a randomised trial | Lancet, The | 2001 | 1,322 |
| 13 | EAU Guidelines on Prostate Cancer. Part II: Treatment of Advanced, Relapsing, and Castration-Resistant Prostate Cancer | European Urology | 2014 | 1,304 |
| 14 | A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes | Nature Genetics | 2004 | 1,226 |
| 15 | Identification and isolation of a 140 kd cell surface glycoprotein with properties expected of a fibronectin receptor | Cell | 1985 | 1,101 |
| 16 | Anchorage dependence, integrins, and apoptosis | Cell | 1994 | 1,011 |
| 17 | Suppression of experimental glomerulonephritis by antiserum against transforming growth factor β1 | Nature | 1990 | 1,006 |
| 18 | The antioxidant function of the p53 tumor suppressor | Nature Medicine | 2005 | 998 |
| 19 | The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene | Cell | 1990 | 995 |
| 20 | Natural inhibitor of transforming growth factor-β protects against scarring in experimental kidney disease | Nature | 1992 | 988 |
| 21 | Platelet membrane glycoprotein IIb/IIIa: member of a family of Arg-Gly-Asp--specific adhesion receptors | Science | 1986 | 936 |
| 22 | Interaction of the small interstitial proteoglycans biglycan, decorin and fibromodulin with transforming growth factor β | Biochemical Journal | 1994 | 930 |
| 23 | Coadministration of a Tumor-Penetrating Peptide Enhances the Efficacy of Cancer Drugs | Science | 2010 | 926 |
| 24 | Recognition of haemagglutinins on virus-infected cells by NKp46 activates lysis by human NK cells | Nature | 2001 | 844 |
| 25 | Elevated levels of the α5β1 fibronectin receptor suppress the transformed phenotype of Chinese hamster ovary cells | Cell | 1990 | 781 |
| 26 | Childhood Acute Lymphoblastic Leukemia: Progress Through Collaboration | Journal of Clinical Oncology | 2015 | 747 |
| 27 | Systematic identification of abundant A-to-I editing sites in the human transcriptome | Nature Biotechnology | 2004 | 740 |
| 28 | Structure and Biology of Proteoglycans | Annual Review of Cell Biology | 1988 | 664 |
| 29 | A new retinoic acid receptor identified from a hepatocellular carcinoma | Nature | 1988 | 619 |
| 30 | bcl-2 gene hypomethylation and high-level expression in B-cell chronic lymphocytic leukemia | Blood | 1993 | 611 |
| 31 | Influence of stereochemistry of the sequence Arg-Gly-Asp-Xaa on binding specificity in cell adhesion. | Journal of Biological Chemistry | 1987 | 607 |
| 32 | The alpha 5 beta 1 integrin supports survival of cells on fibronectin and up-regulates Bcl-2 expression. | Proceedings of the National Academy of Sciences of the United States of America | 1995 | 579 |
| 33 | Guanosine triphosphatase activating protein (GAP) interacts with the p21 ras effector binding domain | Science | 1988 | 537 |
| 34 | Proteoglycans in cell regulation | Journal of Biological Chemistry | 1989 | 514 |
| 35 | Influence of stereochemistry of the sequence Arg-Gly-Asp-Xaa on binding specificity in cell adhesion | Journal of Biological Chemistry | 1987 | 423 |
| 36 | Palonosetron improves prevention of chemotherapy-induced nausea and vomiting following moderately emetogenic chemotherapy: results of a double-blind randomized phase III trial comparing single doses of palonosetron with ondansetron | Annals of Oncology | 2003 | 410 |
| 37 | BCL-2 family proteins: Regulators of cell death involved in the pathogenesis of cancer and resistance to therapy | Journal of Cellular Biochemistry | 1996 | 409 |
| 38 | Regulation of the fibronectin receptor affinity by divalent cations. | Journal of Biological Chemistry | 1988 | 401 |
| 39 | Survival of recombinant erythropoietin in the circulation: the role of carbohydrates | Blood | 1989 | 381 |
| 40 | Diagnostic Assay Based on hsa-miR-205 Expression Distinguishes Squamous From Nonsquamous Non–Small-Cell Lung Carcinoma | Journal of Clinical Oncology | 2009 | 381 |
| 41 | Intravenous ibandronate reduces the incidence of skeletal complications in patients with breast cancer and bone metastases | Annals of Oncology | 2003 | 373 |
| 42 | Association of insulin receptor substrate-1 with integrins | Science | 1994 | 363 |
| 43 | Phage Libraries Displaying Cyclic Peptides with Different Ring Sizes: Ligand Specificities of the RGD-Directed Integrins | Nature Biotechnology | 1995 | 359 |
| 44 | Merosin, a protein specific for basement membranes of Schwann cells, striated muscle, and trophoblast, is expressed late in nerve and muscle development. | Proceedings of the National Academy of Sciences of the United States of America | 1988 | 342 |
| 45 | Distribution and isolation of four laminin variants; tissue restricted distribution of heterotrimers assembled from five different subunits. | Molecular Biology of the Cell | 1990 | 336 |
| 46 | Oral ibandronate reduces the risk of skeletal complications in breast cancer patients with metastatic bone disease: results from two randomised, placebo-controlled phase III studies | British Journal of Cancer | 2004 | 332 |
| 47 | PROTEINKINASECθINT CELLACTIVATION | Annual Review of Immunology | 2002 | 331 |
| 48 | Vitronectin—A major cell attachment-promoting protein in fetal bovine serum | Experimental Cell Research | 1985 | 325 |
| 49 | Dual regulatory role for thyroid-hormone receptors allows control of retinoic-acid receptor activity | Nature | 1989 | 325 |
| 50 | Activation of protein kinase C precedes alpha 5 beta 1 integrin-mediated cell spreading on fibronectin. | Journal of Biological Chemistry | 1993 | 325 |
