| # | Title | Journal | Year | Citations |
|---|
| 1 | Modified Glomerular Filtration Rate Estimating Equation for Chinese Patients with Chronic Kidney Disease | Journal of the American Society of Nephrology: JASN | 2006 | 1,580 |
| 2 | Randomized, Double-Blind, Placebo-Controlled Phase III Trial of Apatinib in Patients With Chemotherapy-Refractory Advanced or Metastatic Adenocarcinoma of the Stomach or Gastroesophageal Junction | Journal of Clinical Oncology | 2016 | 756 |
| 3 | Long noncoding RNA high expression in hepatocellular carcinoma facilitates tumor growth through enhancer of zeste homolog 2 in humans | Hepatology | 2011 | 594 |
| 4 | Epidemiology of Esophageal Cancer in Japan and China | Journal of Epidemiology | 2013 | 476 |
| 5 | Chemical and Pharmacological Research of the Plants in Genus Euphorbia | Chemical Reviews | 2008 | 406 |
| 6 | Alterations in Conserved Kir Channel-PIP2 Interactions Underlie Channelopathies | Neuron | 2002 | 368 |
| 7 | Plasma microRNAs as potential biomarkers for non-small-cell lung cancer | Laboratory Investigation | 2011 | 361 |
| 8 | Constituents from Salvia Species and Their Biological Activities | Chemical Reviews | 2012 | 348 |
| 9 | The acute nociceptive signals induced by bradykinin in rat sensory neurons are mediated by inhibition of M-type K+ channels and activation of Ca2+-activated Cl– channels | Journal of Clinical Investigation | 2010 | 264 |
| 10 | Identification and characterization of neuroblasts in the subventricular zone and rostral migratory stream of the adult human brain | Cell Research | 2011 | 262 |
| 11 | Evaluating glymphatic pathway function utilizing clinically relevant intrathecal infusion of CSF tracer | Journal of Translational Medicine | 2013 | 262 |
| 12 | ‘Hit & Run’ Model of Closed-Skull Traumatic Brain Injury (TBI) Reveals Complex Patterns of Post-Traumatic AQP4 Dysregulation | Journal of Cerebral Blood Flow and Metabolism | 2013 | 240 |
| 13 | The regulation of FOXO1 and its role in disease progression | Life Sciences | 2018 | 234 |
| 14 | Quercetin Inhibit Human SW480 Colon Cancer Growth in Association with Inhibition of Cyclin D1and Survivin Expression through Wnt/β-Catenin Signaling Pathway | Cancer Investigation | 2009 | 206 |
| 15 | CSH guidelines for the diagnosis and treatment of drug-induced liver injury | Hepatology International | 2017 | 206 |
| 16 | Development of a SERS-based lateral flow immunoassay for rapid and ultra-sensitive detection of anti-SARS-CoV-2 IgM/IgG in clinical samples | Sensors and Actuators B: Chemical | 2021 | 206 |
| 17 | Downregulation of miR-486-5p contributes to tumor progression and metastasis by targeting protumorigenic ARHGAP5 in lung cancer | Oncogene | 2014 | 202 |
| 18 | Risk of fracture with thiazolidinediones: An updated meta-analysis of randomized clinical trials | Bone | 2014 | 200 |
| 19 | An ultra-sensitive acetylcholinesterase biosensor based on reduced graphene oxide-Au nanoparticles-β-cyclodextrin/Prussian blue-chitosan nanocomposites for organophosphorus pesticides detection | Biosensors and Bioelectronics | 2015 | 199 |
| 20 | Inflammation and atherosclerosis: signaling pathways and therapeutic intervention | Signal Transduction and Targeted Therapy | 2022 | 190 |
| 21 | The Common Inhalational Anesthetic Isoflurane Induces Apoptosis via Activation of Inositol 1,4,5-Trisphosphate Receptors | Anesthesiology | 2008 | 176 |
| 22 | Natural Taxanes: Developments Since 1828 | Chemical Reviews | 2011 | 175 |
| 23 | miR‐146a and Krüppel‐like factor 4 form a feedback loop to participate in vascular smooth muscle cell proliferation | EMBO Reports | 2011 | 169 |
| 24 | Activation of the Cl − Channel ANO1 by Localized Calcium Signals in Nociceptive Sensory Neurons Requires Coupling with the IP 3 Receptor | Science Signaling | 2013 | 168 |
| 25 | Clinical Benefit of Statin Pretreatment in Patients Undergoing Percutaneous Coronary Intervention | Circulation | 2011 | 166 |
| 26 | Genome-wide association study identifies five loci associated with susceptibility to pancreatic cancer in Chinese populations | Nature Genetics | 2012 | 164 |
| 27 | Characteristic Interactions with Phosphatidylinositol 4,5-Bisphosphate Determine Regulation of Kir Channels by Diverse Modulators | Journal of Biological Chemistry | 2004 | 162 |
| 28 | Human SEIPIN Binds Anionic Phospholipids | Developmental Cell | 2018 | 159 |
| 29 | N-terminal transmembrane domain of the SUR controls trafficking and gating of Kir6 channel subunits | EMBO Journal | 2003 | 156 |
| 30 | Evaluation of the Chronic Kidney Disease Epidemiology Collaboration equation for estimating glomerular filtration rate in the Chinese population | Nephrology Dialysis Transplantation | 2013 | 156 |
| 31 | National incidence of traumatic fractures in China: a retrospective survey of 512 187 individuals | The Lancet Global Health | 2017 | 155 |
| 32 | Chronic Noncommunicable Diseases in 6 Low- and Middle-Income Countries: Findings From Wave 1 of the World Health Organization's Study on Global Ageing and Adult Health (SAGE) | American Journal of Epidemiology | 2017 | 152 |
| 33 | Mesenchymal stem cells: a potential targeted-delivery vehicle for anti-cancer drug loaded nanoparticles | Nanomedicine: Nanotechnology, Biology, and Medicine | 2013 | 151 |
| 34 | Significance of perihematomal edema in acute intracerebral hemorrhage | Neurology | 2009 | 147 |
| 35 | Knockdown of ferroportin accelerates erastin-induced ferroptosis in neuroblastoma cells | European Review for Medical and Pharmacological Sciences | 2018 | 144 |
| 36 | MicroRNA-218 Inhibits Cell Cycle Progression and Promotes Apoptosis in Colon Cancer by Downregulating BMI1 Polycomb Ring Finger Oncogene | Molecular Medicine | 2012 | 142 |
| 37 | NLRP3 deficiency ameliorates renal inflammation and fibrosis in diabetic mice | Molecular and Cellular Endocrinology | 2018 | 142 |
| 38 | A comparison of the Mini-Mental State Examination (MMSE) with the Montreal Cognitive Assessment (MoCA) for mild cognitive impairment screening in Chinese middle-aged and older population: a cross-sectional study | BMC Psychiatry | 2021 | 138 |
| 39 | CpG methylation patterns of human mitochondrial DNA | Scientific Reports | 2016 | 137 |
| 40 | Nuclear actin and actin‐binding proteins in the regulation of transcription and gene expression | FEBS Journal | 2009 | 135 |
| 41 | Dysregulation of p53-RBM25-mediated circAMOTL1L biogenesis contributes to prostate cancer progression through the circAMOTL1L-miR-193a-5p-Pcdha pathway | Oncogene | 2019 | 135 |
| 42 | Therapeutic Benefit of Human Umbilical Cord Derived Mesenchymal Stromal Cells in Intracerebral Hemorrhage Rat: Implications of Anti-inflammation and Angiogenesis | Cellular Physiology and Biochemistry | 2009 | 131 |
| 43 | Anti-inflammatory effects of zinc and alterations in zinc transporter mRNA in mouse models of allergic inflammation | American Journal of Physiology - Lung Cellular and Molecular Physiology | 2007 | 128 |
| 44 | Functional bundles of the medial patellofemoral ligament | Knee Surgery, Sports Traumatology, Arthroscopy | 2010 | 128 |
| 45 | A zirconium-porphyrin MOF-based ratiometric fluorescent biosensor for rapid and ultrasensitive detection of chloramphenicol | Biosensors and Bioelectronics | 2020 | 126 |
| 46 | Monkeypox virus: a re-emergent threat to humans | Virologica Sinica | 2022 | 124 |
| 47 | Salidroside attenuates beta amyloid-induced cognitive deficits via modulating oxidative stress and inflammatory mediators in rat hippocampus | Behavioural Brain Research | 2013 | 123 |
| 48 | Prevalence and Secular Trends in Obesity Among Chinese Adults, 1991−2011 | American Journal of Preventive Medicine | 2015 | 122 |
| 49 | PSA-responsive and PSMA-mediated multifunctional liposomes for targeted therapy of prostate cancer | Biomaterials | 2013 | 121 |
| 50 | Gegen Qinlian decoction enhances the effect of PD-1 blockade in colorectal cancer with microsatellite stability by remodelling the gut microbiota and the tumour microenvironment | Cell Death and Disease | 2019 | 121 |
