| # | Title | Journal | Year | Citations |
|---|
| 1 | Dementia prevention, intervention, and care: 2020 report of the Lancet Commission | Lancet, The | 2020 | 4,658 |
| 2 | Biological, clinical and population relevance of 95 loci for blood lipids | Nature | 2010 | 3,249 |
| 3 | Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing | Nature Genetics | 2019 | 1,962 |
| 4 | Screening for Colorectal Cancer | JAMA - Journal of the American Medical Association | 2016 | 1,725 |
| 5 | Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease | Nature Genetics | 2011 | 1,676 |
| 6 | Prevention and treatment of low back pain: evidence, challenges, and promising directions | Lancet, The | 2018 | 1,363 |
| 7 | The Use of Computed Tomography in Pediatrics and the Associated Radiation Exposure and Estimated Cancer Risk | JAMA Pediatrics | 2013 | 1,123 |
| 8 | Opioid Prescriptions for Chronic Pain and Overdose | Annals of Internal Medicine | 2010 | 1,109 |
| 9 | Screening for Depression in Adults | JAMA - Journal of the American Medical Association | 2016 | 1,086 |
| 10 | Analysis of shared heritability in common disorders of the brain | Science | 2018 | 1,085 |
| 11 | Psychometric assessment of three newly developed implementation outcome measures | Implementation Science | 2017 | 960 |
| 12 | Screening for Prostate Cancer | JAMA - Journal of the American Medical Association | 2018 | 876 |
| 13 | Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data | Nature Biotechnology | 2013 | 846 |
| 14 | Cumulative Use of Strong Anticholinergics and Incident Dementia | JAMA Internal Medicine | 2015 | 843 |
| 15 | Use of Interrupted Time Series Analysis in Evaluating Health Care Quality Improvements | Academic Pediatrics | 2013 | 769 |
| 16 | Durability of Responses after SARS-CoV-2 mRNA-1273 Vaccination | New England Journal of Medicine | 2021 | 665 |
| 17 | The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future | Genetics in Medicine | 2013 | 611 |
| 18 | A Comparison of the Prevalence of Dementia in the United States in 2000 and 2012 | JAMA Internal Medicine | 2017 | 611 |
| 19 | Antibody Persistence through 6 Months after the Second Dose of mRNA-1273 Vaccine for Covid-19 | New England Journal of Medicine | 2021 | 603 |
| 20 | Screening for Obesity in Children and Adolescents | JAMA - Journal of the American Medical Association | 2017 | 588 |
| 21 | US Health Care Spending by Payer and Health Condition, 1996-2016 | JAMA - Journal of the American Medical Association | 2020 | 587 |
| 22 | Multi-ethnic genome-wide association study for atrial fibrillation | Nature Genetics | 2018 | 552 |
| 23 | Evaluation of the Patient Health Questionnaire-9 Item for Detecting Major Depression Among Adolescents | Pediatrics | 2010 | 551 |
| 24 | Benefits and Risks of Bariatric Surgery in Adults | JAMA - Journal of the American Medical Association | 2020 | 541 |
| 25 | Using the E-Value to Assess the Potential Effect of Unmeasured Confounding in Observational Studies | JAMA - Journal of the American Medical Association | 2019 | 525 |
| 26 | Statistical software for analyzing the health effects of multiple concurrent exposures via Bayesian kernel machine regression | Environmental Health | 2018 | 506 |
| 27 | Screening for Thyroid Cancer | JAMA - Journal of the American Medical Association | 2017 | 500 |
| 28 | Effect of Mindfulness-Based Stress Reduction vs Cognitive Behavioral Therapy or Usual Care on Back Pain and Functional Limitations in Adults With Chronic Low Back Pain | JAMA - Journal of the American Medical Association | 2016 | 499 |
| 29 | Acupuncture for Chronic Pain: Update of an Individual Patient Data Meta-Analysis | Journal of Pain | 2018 | 494 |
| 30 | The Group Health Medical Home At Year Two: Cost Savings, Higher Patient Satisfaction, And Less Burnout For Providers | Health Affairs | 2010 | 476 |
| 31 | Risk of Heart Failure in Breast Cancer Patients After Anthracycline and Trastuzumab Treatment: A Retrospective Cohort Study | Journal of the National Cancer Institute | 2012 | 469 |
| 32 | Health Care Contacts in the Year Before Suicide Death | Journal of General Internal Medicine | 2014 | 468 |
| 33 | Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure | Nature Communications | 2020 | 466 |
| 34 | Statin Use for the Primary Prevention of Cardiovascular Disease in Adults | JAMA - Journal of the American Medical Association | 2016 | 459 |
| 35 | Durability of mRNA-1273 vaccine–induced antibodies against SARS-CoV-2 variants | Science | 2021 | 459 |
| 36 | Diagnostic Accuracy of Digital Screening Mammography With and Without Computer-Aided Detection | JAMA Internal Medicine | 2015 | 452 |
| 37 | Type 2 Diabetes as a Risk Factor for Dementia in Women Compared With Men: A Pooled Analysis of 2.3 Million People Comprising More Than 100,000 Cases of Dementia | Diabetes Care | 2016 | 450 |
| 38 | Surveillance for Adverse Events After COVID-19 mRNA Vaccination | JAMA - Journal of the American Medical Association | 2021 | 442 |
| 39 | Depression and Advanced Complications of Diabetes | Diabetes Care | 2010 | 423 |
| 40 | Using the Consolidated Framework for Implementation Research (CFIR) to produce actionable findings: a rapid-cycle evaluation approach to improving implementation | Implementation Science | 2017 | 420 |
| 41 | Does Response on the PHQ-9 Depression Questionnaire Predict Subsequent Suicide Attempt or Suicide Death? | Psychiatric Services | 2013 | 419 |
| 42 | The test-negative design for estimating influenza vaccine effectiveness | Vaccine | 2013 | 406 |
| 43 | New gene functions in megakaryopoiesis and platelet formation | Nature | 2011 | 401 |
| 44 | Self-monitoring of blood pressure in hypertension: A systematic review and individual patient data meta-analysis | PLoS Medicine | 2017 | 401 |
| 45 | Trends in the incidence and prevalence of Alzheimer's disease, dementia, and cognitive impairment in the United States | Alzheimer's and Dementia | 2011 | 399 |
| 46 | Safety and Immunogenicity of Tetanus Diphtheria and Acellular Pertussis (Tdap) Immunization During Pregnancy in Mothers and Infants | JAMA - Journal of the American Medical Association | 2014 | 397 |
| 47 | Estimation of Benefits, Burden, and Harms of Colorectal Cancer Screening Strategies | JAMA - Journal of the American Medical Association | 2016 | 388 |
| 48 | Opioids for low back pain | BMJ, The | 2015 | 387 |
| 49 | Representativeness of the Patient-Reported Outcomes Measurement Information System Internet panel | Journal of Clinical Epidemiology | 2010 | 383 |
| 50 | The Epidemic of Extended-Spectrum-β-Lactamase-Producing Escherichia coli ST131 Is Driven by a Single Highly Pathogenic Subclone, H 30-Rx | MBio | 2013 | 380 |
