| # | Title | Journal | Year | Citations |
|---|
| 1 | Biological, clinical and population relevance of 95 loci for blood lipids | Nature | 2010 | 3,249 |
| 2 | Organizing Care for Patients with Chronic Illness | Milbank Quarterly | 1996 | 2,245 |
| 3 | Collaborative Care Management of Late-Life Depression in the Primary Care Setting | JAMA - Journal of the American Medical Association | 2002 | 2,031 |
| 4 | Gestational Diabetes and the Incidence of Type 2 Diabetes: A systematic review | Diabetes Care | 2002 | 1,905 |
| 5 | A hierarchical regression approach to meta-analysis of diagnostic test accuracy evaluations | Statistics in Medicine | 2001 | 1,205 |
| 6 | Exercise Is Associated with Reduced Risk for Incident Dementia among Persons 65 Years of Age and Older | Annals of Internal Medicine | 2006 | 1,156 |
| 7 | A copy number variation morbidity map of developmental delay | Nature Genetics | 2011 | 1,141 |
| 8 | Association Between Obesity and Psychiatric Disorders in the US Adult Population | Archives of General Psychiatry | 2006 | 1,074 |
| 9 | Outcome Measures for Low Back Pain Research | Spine | 1998 | 1,064 |
| 10 | An International Study of the Relation between Somatic Symptoms and Depression | New England Journal of Medicine | 1999 | 1,056 |
| 11 | Collaborative Management of Chronic Illness | Annals of Internal Medicine | 1997 | 1,002 |
| 12 | Relationship of Depression and Diabetes Self-Care, Medication Adherence, and Preventive Care | Diabetes Care | 2004 | 921 |
| 13 | Common Chronic Pain Conditions in Developed and Developing Countries: Gender and Age Differences and Comorbidity With Depression-Anxiety Disorders | Journal of Pain | 2008 | 918 |
| 14 | Mood Disorders in the Medically Ill: Scientific Review and Recommendations | Biological Psychiatry | 2005 | 913 |
| 15 | Breast Density as a Predictor of Mammographic Detection: Comparison of Interval- and Screen-Detected Cancers | Journal of the National Cancer Institute | 2000 | 865 |
| 16 | Impact of mHealth Chronic Disease Management on Treatment Adherence and Patient Outcomes: A Systematic Review | Journal of Medical Internet Research | 2015 | 864 |
| 17 | Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data | Nature Biotechnology | 2013 | 846 |
| 18 | Acupuncture for Chronic Pain | Archives of Internal Medicine | 2012 | 835 |
| 19 | Reducing Antibiotic Use in Children: A Randomized Trial in 12 Practices | Pediatrics | 2001 | 781 |
| 20 | The association of depression and anxiety with medical symptom burden in patients with chronic medical illness | General Hospital Psychiatry | 2007 | 780 |
| 21 | A Multifaceted Intervention to Improve Treatment of Depression in Primary Care | Archives of General Psychiatry | 1996 | 763 |
| 22 | The Risk of Myocardial Infarction Associated With Antihypertensive Drug Therapies | JAMA - Journal of the American Medical Association | 1995 | 755 |
| 23 | Calcified Coronary Artery Plaque Measurement with Cardiac CT in Population-based Studies: Standardized Protocol of Multi-Ethnic Study of Atherosclerosis (MESA) and Coronary Artery Risk Development in Young Adults (CARDIA) Study | Radiology | 2005 | 746 |
| 24 | Self-management: Enabling and empowering patients living with cancer as a chronic illness | Ca-A Cancer Journal for Clinicians | 2011 | 726 |
| 25 | Exercise Plus Behavioral Management in Patients With Alzheimer Disease | JAMA - Journal of the American Medical Association | 2003 | 653 |
| 26 | The eMERGE Network: A consortium of biorepositories linked to electronic medical records data for conducting genomic studies | BMC Medical Genomics | 2011 | 618 |
| 27 | Clinical Empathy as Emotional Labor in the Patient-Physician Relationship | JAMA - Journal of the American Medical Association | 2005 | 612 |
| 28 | The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future | Genetics in Medicine | 2013 | 611 |
| 29 | Analysis of Case-Cohort Designs | Journal of Clinical Epidemiology | 1999 | 598 |
| 30 | Inviting Patients to Read Their Doctors' Notes: A Quasi-experimental Study and a Look Ahead | Annals of Internal Medicine | 2012 | 575 |
| 31 | Effectiveness of an intervention led by lay health counsellors for depressive and anxiety disorders in primary care in Goa, India (MANAS): a cluster randomised controlled trial | Lancet, The | 2010 | 566 |
| 32 | Effectiveness of Home Blood Pressure Monitoring, Web Communication, and Pharmacist Care on Hypertension Control | JAMA - Journal of the American Medical Association | 2008 | 565 |
| 33 | Effectiveness of Pneumococcal Polysaccharide Vaccine in Older Adults | New England Journal of Medicine | 2003 | 561 |
| 34 | Comparison of the Lay Diagnostic Interview Schedule and a Standardized Psychiatric Diagnosis | Archives of General Psychiatry | 1985 | 552 |
| 35 | Adult health status of women with histories of childhood abuse and neglect | American Journal of Medicine | 1999 | 548 |
| 36 | The Role of the Primary Care Physician in Patientsʼ Adherence to Antidepressant Therapy | Medical Care | 1995 | 543 |
| 37 | Intimate Partner Violence and Women’s Physical, Mental, and Social Functioning | American Journal of Preventive Medicine | 2006 | 527 |
| 38 | De Facto Long-term Opioid Therapy for Noncancer Pain | Clinical Journal of Pain | 2008 | 527 |
| 39 | Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium | Circulation: Cardiovascular Genetics | 2009 | 519 |
| 40 | Phenotypic Heterogeneity of Genomic Disorders and Rare Copy-Number Variants | New England Journal of Medicine | 2012 | 519 |
| 41 | Effect of Improving Depression Care on Pain and Functional Outcomes Among Older Adults With Arthritis | JAMA - Journal of the American Medical Association | 2003 | 510 |
| 42 | A Chronic Disease Score with Empirically Derived Weights | Medical Care | 1995 | 507 |
| 43 | Assessing Global Pain Severity by Self-Report in Clinical and Health Services Research | Spine | 2000 | 507 |
| 44 | Influence of Computer-Aided Detection on Performance of Screening Mammography | New England Journal of Medicine | 2007 | 504 |
| 45 | Detection of Ductal Carcinoma In Situ in Women Undergoing Screening Mammography | Journal of the National Cancer Institute | 2002 | 503 |
| 46 | Intimate Partner Violence | American Journal of Preventive Medicine | 2006 | 503 |
| 47 | Ultrasonography versus Computed Tomography for Suspected Nephrolithiasis | New England Journal of Medicine | 2014 | 501 |
| 48 | Health care costs associated with depressive and anxiety disorders in primary care | American Journal of Psychiatry | 1995 | 495 |
| 49 | Chronic spinal pain and physical–mental comorbidity in the United States: results from the national comorbidity survey replication | Pain | 2005 | 495 |
| 50 | Mental disorders among persons with chronic back or neck pain: Results from the world mental health surveys | Pain | 2007 | 471 |
