| # | Title | Journal | Year | Citations |
|---|
| 1 | The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic | Nature Reviews Gastroenterology and Hepatology | 2014 | 5,773 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 3 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 4 | Intramuscular interferon beta-1a for disease progression in relapsing multiple sclerosis | Annals of Neurology | 1996 | 2,365 |
| 5 | Estimates of the prevalence of arthritis and selected musculoskeletal disorders in the United States | Arthritis and Rheumatism | 1998 | 2,294 |
| 6 | Guidelines of the American Thyroid Association for the Diagnosis and Management of Thyroid Disease During Pregnancy and Postpartum | Thyroid | 2011 | 2,014 |
| 7 | The Effect of Race and Sex on Physicians' Recommendations for Cardiac Catheterization | New England Journal of Medicine | 1999 | 1,745 |
| 8 | Maps and streams in the auditory cortex: nonhuman primates illuminate human speech processing | Nature Neuroscience | 2009 | 1,462 |
| 9 | Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate | Nature | 1996 | 1,443 |
| 10 | Robust Object Recognition with Cortex-Like Mechanisms | IEEE Transactions on Pattern Analysis and Machine Intelligence | 2007 | 1,408 |
| 11 | Meta-Analysis of the Functional Neuroanatomy of Single-Word Reading: Method and Validation | NeuroImage | 2002 | 1,393 |
| 12 | The InterPro protein families and domains database: 20 years on | Nucleic Acids Research | 2021 | 1,385 |
| 13 | InterPro in 2017—beyond protein family and domain annotations | Nucleic Acids Research | 2017 | 1,358 |
| 14 | InterPro in 2019: improving coverage, classification and access to protein sequence annotations | Nucleic Acids Research | 2019 | 1,291 |
| 15 | A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor | Cell | 1993 | 1,286 |
| 16 | Opportunities and obstacles for deep learning in biology and medicine | Journal of the Royal Society Interface | 2018 | 1,282 |
| 17 | Mechanisms and streams for processing of "what" and "where" in auditory cortex | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 1,281 |
| 18 | Oxidants as Stimulators of Signal Transduction | Free Radical Biology and Medicine | 1997 | 1,252 |
| 19 | Prevalence of Inappropriate Antibiotic Prescriptions Among US Ambulatory Care Visits, 2010-2011 | JAMA - Journal of the American Medical Association | 2016 | 1,250 |
| 20 | Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function | Trends in Pharmacological Sciences | 2006 | 1,237 |
| 21 | The InterPro protein families database: the classification resource after 15 years | Nucleic Acids Research | 2015 | 1,205 |
| 22 | Dual streams of auditory afferents target multiple domains in the primate prefrontal cortex | Nature Neuroscience | 1999 | 1,141 |
| 23 | High-resolution donor-recipient HLA matching contributes to the success of unrelated donor marrow transplantation | Blood | 2007 | 1,105 |
| 24 | Functional magnetic resonance imaging evidence of augmented pain processing in fibromyalgia | Arthritis and Rheumatism | 2002 | 1,098 |
| 25 | Monoclonal antibodies: versatile platforms for cancer immunotherapy | Nature Reviews Immunology | 2010 | 1,056 |
| 26 | The Universal Protein Resource (UniProt): an expanding universe of protein information | Nucleic Acids Research | 2006 | 961 |
| 27 | Probiotics and prebiotics in intestinal health and disease: from biology to the clinic | Nature Reviews Gastroenterology and Hepatology | 2019 | 951 |
| 28 | Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a phase I trial | Gene Therapy | 2000 | 914 |
| 29 | Elastography of breast lesions: initial clinical results. | Radiology | 1997 | 897 |
| 30 | Plasma phospholipids identify antecedent memory impairment in older adults | Nature Medicine | 2014 | 885 |
| 31 | Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens | Nature | 1993 | 877 |
| 32 | Effects of Rofecoxib or Naproxen vs Placebo on Alzheimer Disease Progression | JAMA - Journal of the American Medical Association | 2003 | 862 |
| 33 | Radiochromic film dosimetry: Recommendations of AAPM Radiation Therapy Committee Task Group 55 | Medical Physics | 1998 | 854 |
| 34 | Stress Hormones, Proinflammatory and Antiinflammatory Cytokines, and Autoimmunity | Annals of the New York Academy of Sciences | 2002 | 818 |
| 35 | Lifetime risk of symptomatic knee osteoarthritis | Arthritis and Rheumatism | 2008 | 815 |
| 36 | Demyelination occurring during anti-tumor necrosis factor ? therapy for inflammatory arthritides | Arthritis and Rheumatism | 2001 | 813 |
| 37 | Diagnosis, Evaluation, and Treatment of Hyponatremia: Expert Panel Recommendations | American Journal of Medicine | 2013 | 806 |
| 38 | Efficacy of romiplostim in patients with chronic immune thrombocytopenic purpura: a double-blind randomised controlled trial | Lancet, The | 2008 | 784 |
| 39 | Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders | Nature Reviews Drug Discovery | 2010 | 774 |
| 40 | Attenuated multi–mutated herpes simplex virus–1 for the treatment of malignant gliomas | Nature Medicine | 1995 | 761 |
| 41 | Association between endometriosis and risk of histological subtypes of ovarian cancer: a pooled analysis of case–control studies | Lancet Oncology, The | 2012 | 753 |
| 42 | Efficacy and Safety of Nivolumab Plus Ipilimumab in Patients With Advanced Hepatocellular Carcinoma Previously Treated With Sorafenib | JAMA Oncology | 2020 | 746 |
| 43 | Active Tamoxifen Metabolite Plasma Concentrations After Coadministration of Tamoxifen and the Selective Serotonin Reuptake Inhibitor Paroxetine | Journal of the National Cancer Institute | 2003 | 739 |
| 44 | Sex Differences in Pharmacokinetics and Pharmacodynamics | Clinical Pharmacokinetics | 2009 | 724 |
| 45 | Recovery from spinal cord injury mediated by antibodies to neurite growth inhibitors | Nature | 1995 | 698 |
| 46 | Functional Specialization in Rhesus Monkey Auditory Cortex | Science | 2001 | 694 |
| 47 | Sphingolipid metabolism and cell growth regulation | FASEB Journal | 1996 | 691 |
| 48 | PGC-1 α, A Potential Therapeutic Target for Early Intervention in Parkinson’s Disease | Science Translational Medicine | 2010 | 691 |
| 49 | Lower Risk of Heart Failure and Death in Patients Initiated on Sodium-Glucose Cotransporter-2 Inhibitors Versus Other Glucose-Lowering Drugs | Circulation | 2017 | 672 |
| 50 | A subtype of nicotinic cholinergic receptor in rat brain is composed of alpha 4 and beta 2 subunits and is up-regulated by chronic nicotine treatment | Molecular Pharmacology | 1992 | 669 |
