| # | Title | Journal | Year | Citations |
|---|
| 1 | ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing | Genetics in Medicine | 2013 | 2,186 |
| 2 | Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals | Nature Genetics | 2018 | 1,835 |
| 3 | Practice Guidelines for the Diagnosis and Management of Skin and Soft Tissue Infections: 2014 Update by the Infectious Diseases Society of America | Clinical Infectious Diseases | 2014 | 1,711 |
| 4 | Effect of Tumor-Treating Fields Plus Maintenance Temozolomide vs Maintenance Temozolomide Alone on Survival in Patients With Glioblastoma | JAMA - Journal of the American Medical Association | 2017 | 1,619 |
| 5 | Executive Summary: Practice Guidelines for the Diagnosis and Management of Skin and Soft Tissue Infections: 2014 Update by the Infectious Diseases Society of America | Clinical Infectious Diseases | 2014 | 1,156 |
| 6 | Multiple Recurrent De Novo CNVs, Including Duplications of the 7q11.23 Williams Syndrome Region, Are Strongly Associated with Autism | Neuron | 2011 | 1,146 |
| 7 | Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma | JAMA - Journal of the American Medical Association | 2015 | 982 |
| 8 | Do “Brain-Training” Programs Work? | Psychological Science in the Public Interest: A Journal of the American Psychological Society | 2016 | 810 |
| 9 | Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019 | JAMA Oncology | 2022 | 719 |
| 10 | Proton Pump Inhibitor Use and the Risk of Chronic Kidney Disease | JAMA Internal Medicine | 2016 | 553 |
| 11 | Biobank-driven genomic discovery yields new insight into atrial fibrillation biology | Nature Genetics | 2018 | 547 |
| 12 | Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences | Nature Genetics | 2019 | 536 |
| 13 | Adverse effects of antiepileptic drugs | Lancet Neurology, The | 2012 | 511 |
| 14 | Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program | Nature Genetics | 2018 | 497 |
| 15 | American Society of Addiction Medicine (ASAM) National Practice Guideline for the Use of Medications in the Treatment of Addiction Involving Opioid Use | Journal of Addiction Medicine | 2015 | 474 |
| 16 | Implementing genomic medicine in the clinic: the future is here | Genetics in Medicine | 2013 | 472 |
| 17 | Racial, Economic, and Health Inequality and COVID-19 Infection in the United States | Journal of Racial and Ethnic Health Disparities | 2021 | 471 |
| 18 | Distribution and clinical impact of functional variants in 50,726 whole-exome sequences from the DiscovEHR study | Science | 2016 | 464 |
| 19 | Systematic review: Efficacy and safety of medical marijuana in selected neurologic disorders | Neurology | 2014 | 462 |
| 20 | Ethnic-Specific Prevalence of Peripheral Arterial Disease in the United States | American Journal of Preventive Medicine | 2007 | 445 |
| 21 | Practice guideline update summary: Botulinum neurotoxin for the treatment of blepharospasm, cervical dystonia, adult spasticity, and headache | Neurology | 2016 | 432 |
| 22 | Standardizing terms for clinical pharmacogenetic test results: consensus terms from the Clinical Pharmacogenetics Implementation Consortium (CPIC) | Genetics in Medicine | 2017 | 410 |
| 23 | Evaluating the Clinical Validity of Gene-Disease Associations: An Evidence-Based Framework Developed by the Clinical Genome Resource | American Journal of Human Genetics | 2017 | 403 |
| 24 | Multisociety Consensus Quality Improvement Revised Consensus Statement for Endovascular Therapy of Acute Ischemic Stroke | Journal of Vascular and Interventional Radiology | 2018 | 403 |
| 25 | The management of diabetic foot: A clinical practice guideline by the Society for Vascular Surgery in collaboration with the American Podiatric Medical Association and the Society for Vascular Medicine | Journal of Vascular Surgery | 2016 | 385 |
| 26 | Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases | JAMA Oncology | 2017 | 376 |
| 27 | First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma | Journal of Translational Medicine | 2018 | 376 |
| 28 | Guidelines for Patient Radiation Dose Management | Journal of Vascular and Interventional Radiology | 2009 | 375 |
| 29 | Common genetic variants, acting additively, are a major source of risk for autism | Molecular Autism | 2012 | 357 |
| 30 | Genetic identification of familial hypercholesterolemia within a single U.S. health care system | Science | 2016 | 349 |
| 31 | Practice Guideline for Adult Antibiotic Prophylaxis during Vascular and Interventional Radiology Procedures | Journal of Vascular and Interventional Radiology | 2010 | 348 |
| 32 | Lost Productive Work Time Costs From Health Conditions in the United States: Results From the American Productivity Audit | Journal of Occupational and Environmental Medicine | 2003 | 342 |
| 33 | Return of Genomic Results to Research Participants: The Floor, the Ceiling, and the Choices In Between | American Journal of Human Genetics | 2014 | 342 |
| 34 | The Geisinger MyCode community health initiative: an electronic health record–linked biobank for precision medicine research | Genetics in Medicine | 2016 | 340 |
| 35 | Prevalence and Socioeconomic Impact of Upper Gastrointestinal Disorders in the United States: Results of the US Upper Gastrointestinal Study | Clinical Gastroenterology and Hepatology | 2005 | 339 |
| 36 | Risk factors for drug dependence among out‐patients on opioid therapy in a large US health‐care system | Addiction | 2010 | 316 |
| 37 | Economic and Health Consequences of Selling a Kidney in India | JAMA - Journal of the American Medical Association | 2002 | 310 |
| 38 | Measurement and predictors of resilience among community-dwelling older women | Journal of Psychiatric Research | 2008 | 307 |
| 39 | Quality Improvement Guidelines for Percutaneous Needle Biopsy | Journal of Vascular and Interventional Radiology | 2010 | 298 |
| 40 | Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity | Nature Genetics | 2018 | 286 |
| 41 | PheKB: a catalog and workflow for creating electronic phenotype algorithms for transportability | Journal of the American Medical Informatics Association: JAMIA | 2016 | 284 |
| 42 | Preoperative prediction of type 2 diabetes remission after Roux-en-Y gastric bypass surgery: a retrospective cohort study | Lancet Diabetes and Endocrinology,the | 2014 | 278 |
| 43 | The Cost of Inflammatory Bowel Disease: An Initiative From the Crohn’s & Colitis Foundation | Inflammatory Bowel Diseases | 2020 | 274 |
| 44 | Developmental brain dysfunction: revival and expansion of old concepts based on new genetic evidence | Lancet Neurology, The | 2013 | 268 |
| 45 | Understanding the pathogenesis of abdominal aortic aneurysms | Expert Review of Cardiovascular Therapy | 2015 | 262 |
| 46 | Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets | Nature Genetics | 2017 | 257 |
| 47 | Artificial Intelligence Transforms the Future of Health Care | American Journal of Medicine | 2019 | 255 |
| 48 | Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls | Nature | 2019 | 248 |
| 49 | Quality Improvement Guidelines for Percutaneous Transcatheter Embolization | Journal of Vascular and Interventional Radiology | 2010 | 246 |
| 50 | Continuous Innovation In Health Care: Implications Of The Geisinger Experience | Health Affairs | 2008 | 236 |
