| # | Title | Journal | Year | Citations |
|---|
| 1 | LIGAND: A versatile computerized approach for characterization of ligand-binding systems | Analytical Biochemistry | 1980 | 8,732 |
| 2 | Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose | Proceedings of the National Academy of Sciences of the United States of America | 1972 | 7,134 |
| 3 | The Genome Sequence of Drosophila melanogaster | Science | 2000 | 5,566 |
| 4 | Genomic Expression Programs in the Response of Yeast Cells to Environmental Changes | Molecular Biology of the Cell | 2000 | 4,281 |
| 5 | The BDNF val66met Polymorphism Affects Activity-Dependent Secretion of BDNF and Human Memory and Hippocampal Function | Cell | 2003 | 3,472 |
| 6 | What's the Relative Risk? | JAMA - Journal of the American Medical Association | 1998 | 3,365 |
| 7 | Circulating Angiogenic Factors and the Risk of Preeclampsia | New England Journal of Medicine | 2004 | 3,158 |
| 8 | Bullying Behaviors Among US Youth | JAMA - Journal of the American Medical Association | 2001 | 2,850 |
| 9 | In vivo fiber tractography using DT-MRI data | Magnetic Resonance in Medicine | 2000 | 2,778 |
| 10 | Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets | Cell | 2009 | 2,754 |
| 11 | The Transcriptional Coactivators p300 and CBP Are Histone Acetyltransferases | Cell | 1996 | 2,691 |
| 12 | Reliability of diagnosing bacterial vaginosis is improved by a standardized method of gram stain interpretation | Journal of Clinical Microbiology | 1991 | 2,688 |
| 13 | National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: I. The 2014 Diagnosis and Staging Working Group Report | Biology of Blood and Marrow Transplantation | 2015 | 2,636 |
| 14 | Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription | Nature Genetics | 1998 | 2,484 |
| 15 | The Hypothalamic–Pituitary–Adrenal Axis and Immune-Mediated Inflammation | New England Journal of Medicine | 1995 | 2,378 |
| 16 | Neonatal Outcomes of Extremely Preterm Infants From the NICHD Neonatal Research Network | Pediatrics | 2010 | 2,252 |
| 17 | The Diagnosis of Cushing's Syndrome: An Endocrine Society Clinical Practice Guideline | Journal of Clinical Endocrinology and Metabolism | 2008 | 2,131 |
| 18 | Late-Onset Sepsis in Very Low Birth Weight Neonates: The Experience of the NICHD Neonatal Research Network | Pediatrics | 2002 | 2,061 |
| 19 | Trends in Care Practices, Morbidity, and Mortality of Extremely Preterm Neonates, 1993-2012 | JAMA - Journal of the American Medical Association | 2015 | 2,008 |
| 20 | In Vivo Imaging of Embryonic Vascular Development Using Transgenic Zebrafish | Developmental Biology | 2002 | 1,917 |
| 21 | Signals for Sorting of Transmembrane Proteins to Endosomes and Lysosomes | Annual Review of Biochemistry | 2003 | 1,850 |
| 22 | Brefeldin A: insights into the control of membrane traffic and organelle structure. | Journal of Cell Biology | 1992 | 1,827 |
| 23 | Measurement invariance conventions and reporting: The state of the art and future directions for psychological research | Developmental Review | 2016 | 1,826 |
| 24 | Defining the role of common variation in the genomic and biological architecture of adult human height | Nature Genetics | 2014 | 1,818 |
| 25 | NMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurones | Nature | 1986 | 1,777 |
| 26 | Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: Evidence for membrane cycling from Golgi to ER | Cell | 1989 | 1,710 |
| 27 | Soluble Endoglin and Other Circulating Antiangiogenic Factors in Preeclampsia | New England Journal of Medicine | 2006 | 1,666 |
| 28 | Soluble endoglin contributes to the pathogenesis of preeclampsia | Nature Medicine | 2006 | 1,653 |
| 29 | The Mechanisms of Vesicle Budding and Fusion | Cell | 2004 | 1,628 |
| 30 | Targeted Disruption of the α Isoform of the Peroxisome Proliferator-Activated Receptor Gene in Mice Results in Abolishment of the Pleiotropic Effects of Peroxisome Proliferators | Molecular and Cellular Biology | 1995 | 1,585 |
| 31 | Lattice light-sheet microscopy: Imaging molecules to embryos at high spatiotemporal resolution | Science | 2014 | 1,567 |
| 32 | A Photoactivatable GFP for Selective Photolabeling of Proteins and Cells | Science | 2002 | 1,518 |
| 33 | Imaging coexisting fluid domains in biomembrane models coupling curvature and line tension | Nature | 2003 | 1,444 |
| 34 | A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A | Nature | 1996 | 1,442 |
| 35 | Overadjustment Bias and Unnecessary Adjustment in Epidemiologic Studies | Epidemiology | 2009 | 1,441 |
| 36 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 37 | Regulatory RNAs in Bacteria | Cell | 2009 | 1,404 |
| 38 | Plasticity in gray and white: neuroimaging changes in brain structure during learning | Nature Neuroscience | 2012 | 1,358 |
| 39 | The Inconsistency of “Optimal” Cutpoints Obtained using Two Criteria based on the Receiver Operating Characteristic Curve | American Journal of Epidemiology | 2006 | 1,354 |
| 40 | ENDOCRINOLOGY OF THE STRESS RESPONSE | Annual Review of Physiology | 2005 | 1,322 |
| 41 | A definition of dyslexia | Annals of Dyslexia | 2003 | 1,304 |
| 42 | Termination of autophagy and reformation of lysosomes regulated by mTOR | Nature | 2010 | 1,303 |
| 43 | Normal growth and development in the absence of hepatic insulin-like growth factor I | Proceedings of the National Academy of Sciences of the United States of America | 1999 | 1,291 |
| 44 | Diffusion-tensor MRI: theory, experimental design and data analysis - a technical review | NMR in Biomedicine | 2002 | 1,291 |
| 45 | Phosphoinositides: Tiny Lipids With Giant Impact on Cell Regulation | Physiological Reviews | 2013 | 1,281 |
| 46 | Very Low Birth Weight Outcomes of the National Institute of Child Health and Human Development Neonatal Research Network, January 1995 Through December 1996 | Pediatrics | 2001 | 1,272 |
| 47 | Regulating the fate of mRNA: The control of cellular iron metabolism | Cell | 1993 | 1,266 |
| 48 | Regulation of Cell Fate Decision of Undifferentiated Spermatogonia by GDNF | Science | 2000 | 1,219 |
| 49 | Fruit and vegetable consumption and mortality from all causes, cardiovascular disease, and cancer: systematic review and dose-response meta-analysis of prospective cohort studies | BMJ, The | 2014 | 1,212 |
| 50 | Childhood obesity | Lancet, The | 2010 | 1,203 |
