| # | Title | Journal | Year | Citations |
|---|
| 1 | Classical Renin‐Angiotensin System in Kidney Physiology | Annals of Emergency Medicine | 2014 | 409 |
| 2 | Trim28 Is Required for Epigenetic Stability During Mouse Oocyte to Embryo Transition | Science | 2012 | 287 |
| 3 | Nuclear localization of dengue virus (DENV) 1–4 non-structural protein 5; protection against all 4 DENV serotypes by the inhibitor Ivermectin | Antiviral Research | 2013 | 244 |
| 4 | Insights into RNA unwinding and ATP hydrolysis by the flavivirus NS3 protein | EMBO Journal | 2008 | 221 |
| 5 | ICTV Virus Taxonomy Profile: Pneumoviridae | Journal of General Virology | 2017 | 215 |
| 6 | Efficacy and safety of celgosivir in patients with dengue fever (CELADEN): a phase 1b, randomised, double-blind, placebo-controlled, proof-of-concept trial | Lancet Infectious Diseases, The | 2014 | 187 |
| 7 | Update on Dengue: Epidemiology, Virus Evolution, Antiviral Drugs, and Vaccine Development | Current Infectious Disease Reports | 2010 | 176 |
| 8 | Prevalence of Major Depressive Episode in CKD | American Journal of Kidney Diseases | 2009 | 162 |
| 9 | Targeting triple-negative breast cancer: optimising therapeutic outcomes | Annals of Oncology | 2012 | 141 |
| 10 | Validation of Depression Screening Scales in Patients With CKD | American Journal of Kidney Diseases | 2009 | 111 |
| 11 | Vector-borne diseases | OIE Revue Scientifique Et Technique | 2009 | 100 |
| 12 | On a mouse monoclonal antibody that neutralizes all four dengue virus serotypes | Journal of General Virology | 2009 | 73 |
| 13 | Montreal Cognitive Assessment for the screening and prediction of cognitive decline in early Parkinson's disease | Parkinsonism and Related Disorders | 2014 | 73 |
| 14 | Release of Dengue Virus Genome Induced by a Peptide Inhibitor | PLoS ONE | 2012 | 71 |
| 15 | A Phase II Trial of Hu14.18K322A in Combination with Induction Chemotherapy in Children with Newly Diagnosed High-Risk Neuroblastoma | Clinical Cancer Research | 2019 | 61 |
| 16 | B-Vitamins and Bone Health–A Review of the Current Evidence | Nutrients | 2015 | 60 |
| 17 | Association of Depressive Symptoms with Hippocampal Volume in 1936 Adults | Neuropsychopharmacology | 2014 | 59 |
| 18 | Screening for major and minor depression in a multiethnic sample of Asian primary care patients: A comparison of the nine-item Patient Health Questionnaire (PHQ-9) and the 16-item Quick Inventory of Depressive Symptomatology - Self-Report (QIDS-SR16) | Asia-Pacific Psychiatry | 2013 | 57 |
| 19 | The Magnitude of Dengue Virus NS1 Protein Secretion Is Strain Dependent and Does Not Correlate with Severe Pathologies in the Mouse Infection Model | Journal of Virology | 2012 | 54 |
| 20 | Is prior course of illness relevant to acute or longer-term outcomes in depressed out-patients? A STAR*D report | Psychological Medicine | 2012 | 52 |
| 21 | Structure-guided fragment-based in silico drug design of dengue protease inhibitors | Journal of Computer-Aided Molecular Design | 2011 | 51 |
| 22 | The Influence of Anxiety and Depressive Symptoms During Pregnancy on Birth Size | Paediatric and Perinatal Epidemiology | 2014 | 46 |
| 23 | Does early-onset chronic or recurrent major depression impact outcomes with antidepressant medications? A CO-MED Trial Report | Psychological Medicine | 2013 | 45 |
| 24 | Association of carbamazepine-induced severe cutaneous drug reactions and HLA-B*1502 allele status, and dose and treatment duration in paediatric neurology patients in Singapore | Archives of Disease in Childhood | 2014 | 45 |
| 25 | Outcomes on the pharmacopsychometric triangle in bupropion‐SR vs. buspirone augmentation of citalopram in the STAR*D trial | Acta Psychiatrica Scandinavica | 2012 | 42 |
| 26 | Visual contrast sensitivity in major depressive disorder | Journal of Psychosomatic Research | 2013 | 41 |
| 27 | A Randomized, Double-Blind, Placebo-Controlled Trial of Quetiapine in Patients with Bipolar Disorder, Mixed or Depressed Phase, and Alcohol Dependence | Alcoholism: Clinical and Experimental Research | 2014 | 41 |
| 28 | OPA1: 516 unique variants and 831 patients registered in an updated centralized Variome database | Orphanet Journal of Rare Diseases | 2019 | 39 |
| 29 | Pregnenolone sulfate normalizes schizophrenia-like behaviors in dopamine transporter knockout mice through the AKT/GSK3β pathway | Translational Psychiatry | 2015 | 37 |
| 30 | The English and Chinese versions of the five-level EuroQoL Group's five-dimension questionnaire (EQ-5D) were valid and reliable and provided comparable scores in Asian breast cancer patients | Supportive Care in Cancer | 2013 | 36 |
| 31 | Underlying liver disease influences volumetric changes in the spared hemiliver after selective internal radiation therapy with 90Y in patients with hepatocellular carcinoma | Journal of Digestive Diseases | 2014 | 36 |
| 32 | Brief, unidimensional melancholia rating scales are highly sensitive to the effect of citalopram and may have biological validity: Implications for the Research Domain Criteria (RDoC) | Journal of Affective Disorders | 2014 | 36 |
| 33 | COQ2 gene variants associate with cerebellar subtype of multiple system atrophy in Chinese | Movement Disorders | 2015 | 36 |
| 34 | Exploring the origin and potential for spread of the 2013 dengue outbreak in Luanda, Angola | Global Health Action | 2013 | 35 |
| 35 | Role of lncRNAs in Cellular Aging | Frontiers in Endocrinology | 2016 | 35 |
| 36 | High Affinity Human Antibody Fragments to Dengue Virus Non-Structural Protein 3 | PLoS Neglected Tropical Diseases | 2010 | 34 |
| 37 | Comparing Statistical Models to Predict Dengue Fever Notifications | Computational and Mathematical Methods in Medicine | 2012 | 33 |
| 38 | Bats and Rodents Shape Mammalian Retroviral Phylogeny | Scientific Reports | 2015 | 31 |
| 39 | Fatigue in Nondialysis Chronic Kidney Disease: Correlates and Association with Kidney Outcomes | American Journal of Nephrology | 2019 | 31 |
| 40 | Blocking the PI3K/AKT pathway enhances mammalian reovirus replication by repressing IFN-stimulated genes | Frontiers in Microbiology | 2015 | 29 |
| 41 | Multiplex Reverse Transcription-PCR for Simultaneous Surveillance of Influenza A and B Viruses | Journal of Clinical Microbiology | 2017 | 29 |
| 42 | Prognostic role of adjuvant radiotherapy in triple‐negative breast cancer: A historical cohort study | International Journal of Cancer | 2015 | 28 |
| 43 | Rationale and design of the Chronic Kidney Disease Antidepressant Sertraline Trial (CAST) | Contemporary Clinical Trials | 2013 | 26 |
| 44 | Factors Contributing to Inappropriate Visits of Frequent Attenders and Their Economic Effects at an Emergency Department in Singapore | Academic Emergency Medicine | 2015 | 25 |
| 45 | Novel dengue virus inhibitor 4-HPR activates ATF4 independent of protein kinase R–like Endoplasmic Reticulum Kinase and elevates levels of eIF2α phosphorylation in virus infected cells | Antiviral Research | 2016 | 25 |
| 46 | The Impact of Chronic Depression on Acute and Long-Term Outcomes in a Randomized Trial Comparing Selective Serotonin Reuptake Inhibitor Monotherapy Versus Each of 2 Different Antidepressant Medication Combinations | Journal of Clinical Psychiatry | 2012 | 25 |
| 47 | Maternal Antibody-Mediated Disease Enhancement in Type I Interferon-Deficient Mice Leads to Lethal Disease Associated with Liver Damage | PLoS Neglected Tropical Diseases | 2016 | 24 |
| 48 | Hypothalamus–Pituitary–Thyroid Feedback Control: Implications of Mathematical Modeling and Consequences for Thyrotropin (TSH) and Free Thyroxine (FT4) Reference Ranges | Bulletin of Mathematical Biology | 2014 | 22 |
| 49 | Limited knowledge of chronic kidney disease among primary care patients – a cross-sectional survey | BMC Nephrology | 2012 | 21 |
| 50 | Daily activity level improvement with antidepressant medications predicts long-term clinical outcomes in outpatients with major depressive disorder | Neuropsychiatric Disease and Treatment | 2017 | 21 |
