| # | Title | Journal | Year | Citations |
|---|
| 1 | Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial | Lancet, The | 2002 | 3,147 |
| 2 | Gut microbiota composition correlates with diet and health in the elderly | Nature | 2012 | 2,618 |
| 3 | Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials | Lancet, The | 2010 | 2,064 |
| 4 | DNA methylation-based classification of central nervous system tumours | Nature | 2018 | 1,872 |
| 5 | STOPP/START criteria for potentially inappropriate prescribing in older people: version 2 | Age and Ageing | 2014 | 1,775 |
| 6 | STOPP (Screening Tool of Older Persons Prescriptions) and START (Screening Tool to Alert doctors to Right Treatment). Consensus validation | International Journal of Clinical Pharmacology and Therapeutics | 2008 | 1,203 |
| 7 | Exercise and associated dietary extremes impact on gut microbial diversity | Gut | 2014 | 987 |
| 8 | Clinical Outcomes after Hepatitis C Infection from Contaminated Anti-D Immune Globulin | New England Journal of Medicine | 1999 | 877 |
| 9 | STOPP (Screening Tool of Older Persons' potentially inappropriate Prescriptions): application to acutely ill elderly patients and comparison with Beers' criteria | Age and Ageing | 2008 | 626 |
| 10 | Ticagrelor plus aspirin for 1 month, followed by ticagrelor monotherapy for 23 months vs aspirin plus clopidogrel or ticagrelor for 12 months, followed by aspirin monotherapy for 12 months after implantation of a drug-eluting stent: a multicentre, open-label, randomised superiority trial | Lancet, The | 2018 | 555 |
| 11 | ICON: Food allergy | Journal of Allergy and Clinical Immunology | 2012 | 542 |
| 12 | ECFS best practice guidelines: the 2018 revision | Journal of Cystic Fibrosis | 2018 | 521 |
| 13 | Posterior Reversible Encephalopathy Syndrome in End-Stage Kidney Disease: Not Strictly Posterior or Reversible | American Journal of Nephrology | 2015 | 497 |
| 14 | EFNS guidelines for diagnosis, therapy and prevention of Wernicke encephalopathy | European Journal of Neurology | 2010 | 484 |
| 15 | Crohn's disease | Lancet, The | 2002 | 467 |
| 16 | Effect of fibre, antispasmodics, and peppermint oil in the treatment of irritable bowel syndrome: systematic review and meta-analysis | BMJ: British Medical Journal | 2008 | 454 |
| 17 | Rucaparib in Men With Metastatic Castration-Resistant Prostate Cancer Harboring a BRCA1 or BRCA2 Gene Alteration | Journal of Clinical Oncology | 2020 | 448 |
| 18 | Standardized End Point Definitions for Coronary Intervention Trials: The Academic Research Consortium-2 Consensus Document | Circulation | 2018 | 435 |
| 19 | Prevention of Potentially Inappropriate Prescribing for Elderly Patients: A Randomized Controlled Trial Using STOPP/START Criteria | Clinical Pharmacology and Therapeutics | 2011 | 415 |
| 20 | Microbiota of Human Breast Tissue | Applied and Environmental Microbiology | 2014 | 376 |
| 21 | Inappropriate prescribing in the elderly | Journal of Clinical Pharmacy and Therapeutics | 2007 | 349 |
| 22 | Neuraxial opioid-induced pruritus: a review | Journal of Clinical Anesthesia | 2003 | 344 |
| 23 | Delirium in an adult acute hospital population: predictors, prevalence and detection | BMJ Open | 2013 | 343 |
| 24 | Diagnosis and management of Silver–Russell syndrome: first international consensus statement | Nature Reviews Endocrinology | 2017 | 336 |
| 25 | Plasma cytokine profiles in depressed patients who fail to respond to selective serotonin reuptake inhibitor therapy | Journal of Psychiatric Research | 2007 | 317 |
| 26 | Crohn's disease: factors associated with exposure to high levels of diagnostic radiation | Gut | 2008 | 307 |
| 27 | START (screening tool to alert doctors to the right treatment) an evidence-based screening tool to detect prescribing omissions in elderly patients | Age and Ageing | 2007 | 299 |
| 28 | Ryanodine receptor mutations in malignant hyperthermia and central core disease | Age and Ageing | 2000 | 296 |
| 29 | Alterations in the colonic flora and intestinal permeability and evidence of immune activation in chronic constipation | Digestive and Liver Disease | 2005 | 284 |
| 30 | Prevalence of potentially inappropriate prescribing in an acutely ill population of older patients admitted to six European hospitals | European Journal of Clinical Pharmacology | 2011 | 284 |
| 31 | Predicting risk of adverse drug reactions in older adults | Therapeutic Advances in Drug Safety | 2016 | 276 |
| 32 | Cytokines: abnormalities in major depression and implications for pharmacological treatment | Human Psychopharmacology | 2004 | 271 |
| 33 | Abiraterone plus prednisone added to androgen deprivation therapy and docetaxel in de novo metastatic castration-sensitive prostate cancer (PEACE-1): a multicentre, open-label, randomised, phase 3 study with a 2 × 2 factorial design | Lancet, The | 2022 | 261 |
| 34 | Proprioception in the cruciate deficient knee | Journal of Bone and Joint Surgery: British Volume | 1992 | 255 |
| 35 | The Fas Counterattack In Vivo: Apoptotic Depletion of Tumor-Infiltrating Lymphocytes Associated with Fas Ligand Expression by Human Esophageal Carcinoma | Journal of Immunology | 1998 | 255 |
| 36 | Review: A systematic review of hypothalamic-pituitary-adrenal axis function in schizophrenia: implications for mortality | Journal of Psychopharmacology | 2010 | 251 |
| 37 | Cell Response to Surgery | Archives of Surgery | 2006 | 250 |
| 38 | Zotarolimus-Eluting Versus Bare-Metal Stents in Uncertain Drug-Eluting Stent Candidates | Journal of the American College of Cardiology | 2015 | 248 |
| 39 | Preemptive analgesia I: physiological pathways and pharmacological modalities | Canadian Journal of Anaesthesia | 2001 | 246 |
| 40 | Inappropriate Prescribing | Drugs and Aging | 2012 | 245 |
| 41 | Hyponatremia Independent of Osteoporosis is Associated with Fracture Occurrence | Clinical Journal of the American Society of Nephrology: CJASN | 2010 | 240 |
| 42 | Pravastatin and cognitive function in the elderly. Results of the PROSPER study | Journal of Neurology | 2010 | 238 |
| 43 | Potentially inappropriate prescribing in an Irish elderly population in primary care | British Journal of Clinical Pharmacology | 2009 | 234 |
| 44 | Is Adipose Tissue a Reservoir for Viral Spread, Immune Activation, and Cytokine Amplification in Coronavirus Disease 2019? | Obesity | 2020 | 233 |
| 45 | Inappropriate prescribing in the older population: need for new criteria | Age and Ageing | 2008 | 232 |
| 46 | Proinflammatory Mediators Stimulate Neutrophil-Directed Angiogenesis | Archives of Surgery | 1999 | 231 |
| 47 | A Molecular Analysis of Fecal and Mucosal Bacterial Communities in Irritable Bowel Syndrome | Digestive Diseases and Sciences | 2010 | 228 |
| 48 | DNA Damage Response and Repair Gene Alterations Are Associated with Improved Survival in Patients with Platinum-Treated Advanced Urothelial Carcinoma | Clinical Cancer Research | 2017 | 225 |
| 49 | Risk Factors for Coronary Heart Disease in Type 1 Diabetic Patients in Europe: The EURODIAB Prospective Complications Study | Diabetes Care | 2004 | 224 |
| 50 | The Fas counterattack in vivo: apoptotic depletion of tumor-infiltrating lymphocytes associated with Fas ligand expression by human esophageal carcinoma | Journal of Immunology | 1998 | 219 |
