| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Two dimensional thin layer chromatographic separation of polar lipids and determination of phospholipids by phosphorus analysis of spots | Lipids | 1970 | 3,221 |
| 3 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 4 | Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial | Lancet, The | 2008 | 2,848 |
| 5 | Clinical Practice Guideline for the Use of Antimicrobial Agents in Neutropenic Patients with Cancer: 2010 Update by the Infectious Diseases Society of America | Clinical Infectious Diseases | 2011 | 2,434 |
| 6 | Association of reactive oxygen species levels and radioresistance in cancer stem cells | Nature | 2009 | 2,232 |
| 7 | Binding of soluble form of fibroblast surface protein, fibronectin, to collagen | International Journal of Cancer | 1977 | 1,953 |
| 8 | Quantitative analysis of phospholipids by thin‐layer chromatography and phosphorus analysis of spots | Lipids | 1966 | 1,607 |
| 9 | Long-term outcome in patients with a pathological complete response after chemoradiation for rectal cancer: a pooled analysis of individual patient data | Lancet Oncology, The | 2010 | 1,532 |
| 10 | Long-term safety and activity of axicabtagene ciloleucel in refractory large B-cell lymphoma (ZUMA-1): a single-arm, multicentre, phase 1–2 trial | Lancet Oncology, The | 2019 | 1,467 |
| 11 | Karyotypic analysis predicts outcome of preremission and postremission therapy in adult acute myeloid leukemia: a Southwest Oncology Group/Eastern Cooperative Oncology Group study | Blood | 2000 | 1,442 |
| 12 | The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity | Nature | 2019 | 1,375 |
| 13 | Endogenous Bile Acids Are Ligands for the Nuclear Receptor FXR/BAR | Molecular Cell | 1999 | 1,345 |
| 14 | Venetoclax combined with decitabine or azacitidine in treatment-naive, elderly patients with acute myeloid leukemia | Blood | 2019 | 1,254 |
| 15 | A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes | Nature Genetics | 2004 | 1,226 |
| 16 | Lisocabtagene maraleucel for patients with relapsed or refractory large B-cell lymphomas (TRANSCEND NHL 001): a multicentre seamless design study | Lancet, The | 2020 | 1,224 |
| 17 | The Heidelberg classification of renal cell tumours | Lancet, The | 1997 | 1,142 |
| 18 | Improving the Quality of Spiritual Care as a Dimension of Palliative Care: The Report of the Consensus Conference | Journal of Palliative Medicine | 2009 | 1,084 |
| 19 | The human tumor microbiome is composed of tumor type–specific intracellular bacteria | Science | 2020 | 1,077 |
| 20 | Safety and activity of blinatumomab for adult patients with relapsed or refractory B-precursor acute lymphoblastic leukaemia: a multicentre, single-arm, phase 2 study | Lancet Oncology, The | 2015 | 1,031 |
| 21 | Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3 | Nature Genetics | 2000 | 994 |
| 22 | Systematic Review and Meta-analysis of Studies Reporting Urinary Continence Recovery After Robot-assisted Radical Prostatectomy | European Urology | 2012 | 961 |
| 23 | Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells | Nature Biotechnology | 2002 | 937 |
| 24 | Development of PD-1 and PD-L1 inhibitors as a form of cancer immunotherapy: a comprehensive review of registration trials and future considerations | Nature Biotechnology | 2018 | 936 |
| 25 | Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity | Nature Medicine | 2005 | 917 |
| 26 | Cytokeratin 7 and Cytokeratin 20 Expression in Epithelial Neoplasms: A Survey of 435 Cases | Modern Pathology | 2000 | 916 |
| 27 | The current state and future directions of RNAi-based therapeutics | Nature Reviews Drug Discovery | 2019 | 896 |
| 28 | Breast-cancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis | Nature Cell Biology | 2015 | 895 |
| 29 | Breast Cancer, Version 3.2020, NCCN Clinical Practice Guidelines in Oncology | Journal of the National Comprehensive Cancer Network: JNCCN | 2020 | 848 |
| 30 | Expression in Escherichia coli of a chemically synthesized gene for the hormone somatostatin | Science | 1977 | 845 |
| 31 | The MDM2 gene amplification database | Nucleic Acids Research | 1998 | 843 |
| 32 | The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux | Nature Medicine | 2001 | 798 |
| 33 | The Reward Deficiency Syndrome: A Biogenetic Model for the Diagnosis and Treatment of Impulsive, Addictive and Compulsive Behaviors | Journal of Psychoactive Drugs | 2000 | 794 |
| 34 | R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling | Cell | 2018 | 794 |
| 35 | Molecular Testing Guideline for Selection of Lung Cancer Patients for EGFR and ALK Tyrosine Kinase Inhibitors: Guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology | Journal of Thoracic Oncology | 2013 | 792 |
| 36 | Palifermin for Oral Mucositis after Intensive Therapy for Hematologic Cancers | New England Journal of Medicine | 2004 | 791 |
| 37 | Cabozantinib versus everolimus in advanced renal cell carcinoma (METEOR): final results from a randomised, open-label, phase 3 trial | Lancet Oncology, The | 2016 | 789 |
| 38 | Efficacy of romiplostim in patients with chronic immune thrombocytopenic purpura: a double-blind randomised controlled trial | Lancet, The | 2008 | 784 |
| 39 | METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification | Cell Stem Cell | 2018 | 749 |
| 40 | Breast-Cancer Risk in Families with Mutations in PALB2 | New England Journal of Medicine | 2014 | 745 |
| 41 | Daratumumab monotherapy in patients with treatment-refractory multiple myeloma (SIRIUS): an open-label, randomised, phase 2 trial | Lancet, The | 2016 | 724 |
| 42 | Keratin expression in human tissues and neoplasms | Histopathology | 2002 | 722 |
| 43 | An enhanced International Prognostic Index (NCCN-IPI) for patients with diffuse large B-cell lymphoma treated in the rituximab era | Blood | 2014 | 693 |
| 44 | Nilotinib (formerly AMN107), a highly selective BCR-ABL tyrosine kinase inhibitor, is effective in patients with Philadelphia chromosome–positive chronic myelogenous leukemia in chronic phase following imatinib resistance and intolerance | Blood | 2007 | 688 |
| 45 | Esophageal and Esophagogastric Junction Cancers, Version 2.2019, NCCN Clinical Practice Guidelines in Oncology | Journal of the National Comprehensive Cancer Network: JNCCN | 2019 | 672 |
| 46 | Mutations induced by ultraviolet light | Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis | 2005 | 656 |
| 47 | Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 654 |
| 48 | A Randomized, Controlled Trial of Prophylactic Ganciclovir for Cytomegalovirus Pulmonary Infection in Recipients of Allogeneic Bone Marrow Transplants | New England Journal of Medicine | 1991 | 648 |
| 49 | Executive Summary: Clinical Practice Guideline for the Use of Antimicrobial Agents in Neutropenic Patients with Cancer: 2010 Update by the Infectious Diseases Society of America | Clinical Infectious Diseases | 2011 | 635 |
| 50 | Brentuximab vedotin as consolidation therapy after autologous stem-cell transplantation in patients with Hodgkin's lymphoma at risk of relapse or progression (AETHERA): a randomised, double-blind, placebo-controlled, phase 3 trial | Lancet, The | 2015 | 633 |
