| # | Title | Journal | Year | Citations |
|---|
| 1 | Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis | Nature Medicine | 2013 | 3,355 |
| 2 | Discovery and refinement of loci associated with lipid levels | Nature Genetics | 2013 | 2,641 |
| 3 | Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel | European Heart Journal | 2017 | 2,292 |
| 4 | Cultural Humility Versus Cultural Competence: A Critical Distinction in Defining Physician Training Outcomes in Multicultural Education | Journal of Health Care for the Poor and Underserved | 1998 | 2,268 |
| 5 | Genome sequence, comparative analysis and haplotype structure of the domestic dog | Nature | 2005 | 2,215 |
| 6 | A conditional knockout resource for the genome-wide study of mouse gene function | Nature | 2011 | 1,488 |
| 7 | The Genome Sequence of Trypanosoma cruzi, Etiologic Agent of Chagas Disease | Science | 2005 | 1,273 |
| 8 | Identification of Vaccine Candidates Against Serogroup B Meningococcus by Whole-Genome Sequencing | Science | 2000 | 1,258 |
| 9 | Mutations in a new member of the chromodomain gene family cause CHARGE syndrome | Nature Genetics | 2004 | 1,098 |
| 10 | Statin-associated muscle symptoms: impact on statin therapy—European Atherosclerosis Society Consensus Panel Statement on Assessment, Aetiology and Management | European Heart Journal | 2015 | 1,024 |
| 11 | The Atlantic salmon genome provides insights into rediploidization | Nature | 2016 | 1,021 |
| 12 | From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus | Nature | 2010 | 1,018 |
| 13 | High-throughput discovery of novel developmental phenotypes | Nature | 2016 | 1,001 |
| 14 | The DNA sequence of the human X chromosome | Nature | 2005 | 985 |
| 15 | Low-density lipoproteins cause atherosclerotic cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus statement from the European Atherosclerosis Society Consensus Panel | European Heart Journal | 2020 | 776 |
| 16 | Common variants associated with plasma triglycerides and risk for coronary artery disease | Nature Genetics | 2013 | 754 |
| 17 | Draft Genome Sequence of the Sexually Transmitted Pathogen Trichomonas vaginalis | Science | 2007 | 731 |
| 18 | Basal cell carcinomas: attack of the hedgehog | Nature Reviews Cancer | 2008 | 711 |
| 19 | Hyaluronidases: Their Genomics, Structures, and Mechanisms of Action | Chemical Reviews | 2006 | 675 |
| 20 | Antibacterial Effect of Human Mesenchymal Stem Cells Is Mediated in Part from Secretion of the Antimicrobial Peptide LL-37 | Stem Cells | 2010 | 672 |
| 21 | Allogeneic human mesenchymal stem cells for treatment of E. coli endotoxin-induced acute lung injury in the ex vivo perfused human lung | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 653 |
| 22 | HLA DR-DQ Haplotypes and Genotypes and Type 1 Diabetes Risk | Diabetes | 2008 | 631 |
| 23 | Comparative analyses of multi-species sequences from targeted genomic regions | Nature | 2003 | 584 |
| 24 | HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials | Lancet, The | 2015 | 562 |
| 25 | The animal fatty acid synthase: one gene, one polypeptide, seven enzymes | FASEB Journal | 1994 | 528 |
| 26 | Structural and functional organization of the animal fatty acid synthase | Progress in Lipid Research | 2003 | 519 |
| 27 | Inhibiting the Hedgehog Pathway in Patients with the Basal-Cell Nevus Syndrome | New England Journal of Medicine | 2012 | 490 |
| 28 | Itraconazole, a Commonly Used Antifungal that Inhibits Hedgehog Pathway Activity and Cancer Growth | Cancer Cell | 2010 | 454 |
| 29 | Antiparallel β-sheet: a signature structure of the oligomeric amyloid β-peptide | Biochemical Journal | 2009 | 445 |
| 30 | A Short-Term Trial of Butyrate to Stimulate Fetal-Globin-Gene Expression in the β-Globin Disorders | New England Journal of Medicine | 1993 | 443 |
| 31 | Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs | Neuron | 2016 | 437 |
| 32 | Array-Based Comparative Genomic Hybridization for the Genomewide Detection of Submicroscopic Chromosomal Abnormalities | American Journal of Human Genetics | 2003 | 423 |
| 33 | HDL Measures, Particle Heterogeneity, Proposed Nomenclature, and Relation to Atherosclerotic Cardiovascular Events | Clinical Chemistry | 2011 | 417 |
| 34 | Apo B versus cholesterol in estimating cardiovascular risk and in guiding therapy: report of the thirty-person/ten-country panel | Journal of Internal Medicine | 2006 | 405 |
| 35 | Vaccination against Neisseria meningitidis Using Three Variants of the Lipoprotein GNA1870 | Journal of Experimental Medicine | 2003 | 388 |
| 36 | Selection-free genome editing of the sickle mutation in human adult hematopoietic stem/progenitor cells | Science Translational Medicine | 2016 | 386 |
| 37 | From The Cover: Germ-line epigenetic modification of the murine Avy allele by nutritional supplementation | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 382 |
| 38 | The Clinical Pharmacogenetics Implementation Consortium Guideline for SLCO1B1 and Simvastatin-Induced Myopathy: 2014 Update | Clinical Pharmacology and Therapeutics | 2014 | 379 |
| 39 | Versatile P[acman] BAC libraries for transgenesis studies in Drosophila melanogaster | Nature Methods | 2009 | 375 |
| 40 | Mammalian Long-Chain Acyl-CoA Synthetases | Experimental Biology and Medicine | 2008 | 372 |
| 41 | Energy requirements during pregnancy and lactation | Public Health Nutrition | 2005 | 367 |
| 42 | The Meningococcal Vaccine Candidate GNA1870 Binds the Complement Regulatory Protein Factor H and Enhances Serum Resistance | Journal of Immunology | 2006 | 366 |
| 43 | The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals | Nature Genetics | 2016 | 362 |
| 44 | An overview of evidence for a causal relation between iron deficiency during development and deficits in cognitive or behavioral function | American Journal of Clinical Nutrition | 2007 | 359 |
| 45 | Biomarkers of Nutrition for Development (BOND)—Zinc Review | Journal of Nutrition | 2016 | 359 |
| 46 | Is there convincing biological or behavioral evidence linking vitamin D deficiency to brain dysfunction? | FASEB Journal | 2008 | 355 |
| 47 | Identifying genetic risk factors for serious adverse drug reactions: current progress and challenges | Nature Reviews Drug Discovery | 2007 | 351 |
| 48 | Vitamin D and the omega‐3 fatty acids control serotonin synthesis and action, part 2: relevance for ADHD, bipolar disorder, schizophrenia, and impulsive behavior | FASEB Journal | 2015 | 343 |
| 49 | Food Consumption and its Impact on Cardiovascular Disease: Importance of Solutions Focused on the Globalized Food System | Journal of the American College of Cardiology | 2015 | 343 |
| 50 | Is docosahexaenoic acid, an n−3 long-chain polyunsaturated fatty acid, required for development of normal brain function? An overview of evidence from cognitive and behavioral tests in humans and animals | American Journal of Clinical Nutrition | 2005 | 341 |
