| # | Title | Journal | Year | Citations |
|---|
| 1 | Development of a simple noninvasive index to predict significant fibrosis in patients with HIV/HCV coinfection | Hepatology | 2006 | 3,343 |
| 2 | A systematic review of evidence on the links between patient experience and clinical safety and effectiveness | BMJ Open | 2013 | 1,451 |
| 3 | Third European Evidence-based Consensus on Diagnosis and Management of Ulcerative Colitis. Part 1: Definitions, Diagnosis, Extra-intestinal Manifestations, Pregnancy, Cancer Surveillance, Surgery, and Ileo-anal Pouch Disorders | Journal of Crohn's and Colitis | 2017 | 1,324 |
| 4 | Methods to increase response to postal and electronic questionnaires | The Cochrane Library | 2010 | 885 |
| 5 | The emerging spectrum of COVID-19 neurology: clinical, radiological and laboratory findings | Brain | 2020 | 880 |
| 6 | Neuropathic pain: an updated grading system for research and clinical practice | Pain | 2016 | 824 |
| 7 | Tuberculosis-associated immune reconstitution inflammatory syndrome: case definitions for use in resource-limited settings | Lancet Infectious Diseases, The | 2008 | 681 |
| 8 | Comparison of first-line antiretroviral therapy with regimens including nevirapine, efavirenz, or both drugs, plus stavudine and lamivudine: a randomised open-label trial, the 2NN Study | Lancet, The | 2004 | 665 |
| 9 | Article Commentary: Patient-Reported Outcomes (PROs) and Patient-Reported Outcome Measures (PROMs) | Health Services Insights | 2013 | 661 |
| 10 | Effect of antioxidants on the occurrence of pre-eclampsia in women at increased risk: a randomised trial | Lancet, The | 1999 | 635 |
| 11 | Role of interleukin‐1β in postoperative cognitive dysfunction | Annals of Neurology | 2010 | 623 |
| 12 | Tumor necrosis factor-α triggers a cytokine cascade yielding postoperative cognitive decline | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 600 |
| 13 | Dexmedetomidine for prevention of delirium in elderly patients after non-cardiac surgery: a randomised, double-blind, placebo-controlled trial | Lancet, The | 2016 | 563 |
| 14 | NEW AGENTS FOR SEDATION IN THE INTENSIVE CARE UNIT | Critical Care Clinics | 2001 | 547 |
| 15 | Transdermal oestrogen for treatment of severe postnatal depression | Lancet, The | 1996 | 544 |
| 16 | British HIV Association guidelines for the treatment of HIV‐1‐infected adults with antiretroviral therapy 2008 | HIV Medicine | 2008 | 530 |
| 17 | Tenofovir alafenamide versus tenofovir disoproxil fumarate, coformulated with elvitegravir, cobicistat, and emtricitabine, for initial treatment of HIV-1 infection: two randomised, double-blind, phase 3, non-inferiority trials | Lancet, The | 2015 | 521 |
| 18 | Clinical and MRI Correlates of Cerebral Palsy | JAMA - Journal of the American Medical Association | 2006 | 508 |
| 19 | Efficacy of short-term monotherapy with maraviroc, a new CCR5 antagonist, in patients infected with HIV-1 | Nature Medicine | 2005 | 467 |
| 20 | Once-daily atazanavir/ritonavir versus twice-daily lopinavir/ritonavir, each in combination with tenofovir and emtricitabine, for management of antiretroviral-naive HIV-1-infected patients: 48 week efficacy and safety results of the CASTLE study | Lancet, The | 2008 | 442 |
| 21 | Recommendations for standards of monitoring during anaesthesia and recovery 2015 : Association of Anaesthetists of Great Britain and Ireland | Anaesthesia | 2016 | 403 |
| 22 | Persistence of episomal HIV-1 infection intermediates in patients on highly active anti-retroviral therapy | Nature Medicine | 2000 | 401 |
| 23 | Association of Prior Antibiotic Treatment With Survival and Response to Immune Checkpoint Inhibitor Therapy in Patients With Cancer | JAMA Oncology | 2019 | 396 |
| 24 | Guidelines on the radical management of patients with lung cancer | Thorax | 2010 | 393 |
| 25 | Systemic Inflammatory Priming in Normal Pregnancy and Preeclampsia: The Role of Circulating Syncytiotrophoblast Microparticles | Journal of Immunology | 2007 | 389 |
| 26 | Responses to a 1 month self-report on adherence to antiretroviral therapy are consistent with electronic data and virological treatment outcome | Aids | 2002 | 379 |
| 27 | Outcome of pregnancy in patients with structural or ischaemic heart disease: results of a registry of the European Society of Cardiology | European Heart Journal | 2013 | 378 |
| 28 | Mucosal healing and a fall in mucosal pro-inflammatory cytokine mRNA induced by a specific oral polymeric diet in paediatric Crohn’s disease | Alimentary Pharmacology and Therapeutics | 2000 | 359 |
| 29 | Association of severe intrahepatic cholestasis of pregnancy with adverse pregnancy outcomes: A prospective population‐based case‐control study | Hepatology | 2014 | 347 |
| 30 | Effect of transmitted drug resistance on virological and immunological response to initial combination antiretroviral therapy for HIV (EuroCoord-CHAIN joint project): a European multicohort study | Lancet Infectious Diseases, The | 2011 | 345 |
| 31 | Scoping review on the use of socially assistive robot technology in elderly care | BMJ Open | 2018 | 343 |
| 32 | MR Imaging Evaluation of the Activity of Crohn's Disease | American Journal of Roentgenology | 2001 | 342 |
| 33 | Guidelines for the diagnosis and management of cow's milk protein allergy in infants | Archives of Disease in Childhood | 2007 | 340 |
| 34 | Continuous low dose Thalidomide: a phase II study in advanced melanoma, renal cell, ovarian and breast cancer | British Journal of Cancer | 2000 | 336 |
| 35 | Meteorological conditions, climate change, new emerging factors, and asthma and related allergic disorders. A statement of the World Allergy Organization | World Allergy Organization Journal | 2015 | 328 |
| 36 | Episodic Sexual Transmission of HIV Revealed by Molecular Phylodynamics | PLoS Medicine | 2008 | 326 |
| 37 | Emergence of CXCR4-Using Human Immunodeficiency Virus Type 1 (HIV-1) Variants in a Minority of HIV-1-Infected Patients following Treatment with the CCR5 Antagonist Maraviroc Is from a Pretreatment CXCR4-Using Virus Reservoir | Journal of Virology | 2006 | 317 |
| 38 | Postoperative adhesions | Diseases of the Colon and Rectum | 2001 | 312 |
| 39 | Primary ciliary dyskinesia: current state of the art | Archives of Disease in Childhood | 2007 | 311 |
| 40 | WHO multicentre randomised trial of misoprostol in the management of the third stage of labour | Lancet, The | 2001 | 310 |
| 41 | Early and nonreversible decrease of CD161++/MAIT cells in HIV infection | Blood | 2013 | 307 |
| 42 | Biologic Effects of Nitrous Oxide | Anesthesiology | 2008 | 301 |
| 43 | miR-132 regulates antiviral innate immunity through suppression of the p300 transcriptional co-activator | Nature Cell Biology | 2010 | 301 |
| 44 | Rich-club organization of the newborn human brain | Proceedings of the National Academy of Sciences of the United States of America | 2014 | 300 |
| 45 | Prospective Study of Placental Angiogenic Factors and Maternal Vascular Function Before and After Preeclampsia and Gestational Hypertension | Circulation | 2010 | 299 |
| 46 | Cell salvage in obstetrics | International Journal of Obstetric Anesthesia | 2008 | 289 |
| 47 | The safety of tenofovir disoproxil fumarate for the treatment of HIV infection in adults: the first 4 years | Aids | 2007 | 287 |
| 48 | Efficacy and safety of grazoprevir (MK-5172) and elbasvir (MK-8742) in patients with hepatitis C virus and HIV co-infection (C-EDGE CO-INFECTION): a non-randomised, open-label trial | Lancet HIV,the | 2015 | 285 |
| 49 | Cannabinoid 1 receptors are expressed in nociceptive primary sensory neurons | Neuroscience | 2000 | 283 |
| 50 | Quality at general practice consultations: cross sectional survey | BMJ: British Medical Journal | 1999 | 282 |
