| # | Title | Journal | Year | Citations |
|---|
| 1 | EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update | Annals of the Rheumatic Diseases | 2017 | 3,366 |
| 2 | Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers | JAMA - Journal of the American Medical Association | 2017 | 1,898 |
| 3 | Rheumatoid arthritis | Nature Reviews Disease Primers | 2018 | 1,441 |
| 4 | The efficacy and safety of rituximab in patients with active rheumatoid arthritis despite methotrexate treatment: Results of a phase IIB randomized, double-blind, placebo-controlled, dose-ranging trial | Arthritis and Rheumatism | 2006 | 951 |
| 5 | New therapies for treatment of rheumatoid arthritis | Lancet, The | 2007 | 859 |
| 6 | Comparison of methotrexate monotherapy with a combination of methotrexate and etanercept in active, early, moderate to severe rheumatoid arthritis (COMET): a randomised, double-blind, parallel treatment trial | Lancet, The | 2008 | 744 |
| 7 | Group for Research and Assessment of Psoriasis and Psoriatic Arthritis 2015 Treatment Recommendations for Psoriatic Arthritis | Arthritis and Rheumatology | 2016 | 726 |
| 8 | An explanation for the apparent dissociation between clinical remission and continued structural deterioration in rheumatoid arthritis | Arthritis and Rheumatism | 2008 | 712 |
| 9 | Presence of significant synovitis in rheumatoid arthritis patients with disease-modifying antirheumatic drug–induced clinical remission: Evidence from an imaging study may explain structural progression | Arthritis and Rheumatism | 2006 | 606 |
| 10 | Prenatal exome sequencing analysis in fetal structural anomalies detected by ultrasonography (PAGE): a cohort study | Lancet, The | 2019 | 443 |
| 11 | Treating spondyloarthritis, including ankylosing spondylitis and psoriatic arthritis, to target: recommendations of an international task force | Annals of the Rheumatic Diseases | 2014 | 397 |
| 12 | Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders | Nature Neuroscience | 2016 | 388 |
| 13 | Reduction of fatigue in Sjogren syndrome with rituximab: results of a randomised, double-blind, placebo-controlled pilot study | Annals of the Rheumatic Diseases | 2008 | 381 |
| 14 | Current evidence for the management of rheumatoid arthritis with biological disease-modifying antirheumatic drugs: a systematic literature review informing the EULAR recommendations for the management of RA | Annals of the Rheumatic Diseases | 2010 | 376 |
| 15 | Rheumatoid arthritis association at 6q23 | Nature Genetics | 2007 | 361 |
| 16 | Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer | Nature Genetics | 2017 | 356 |
| 17 | Distinct genetic architectures for syndromic and nonsyndromic congenital heart defects identified by exome sequencing | Nature Genetics | 2016 | 351 |
| 18 | High Rate of Recurrent De Novo Mutations in Developmental and Epileptic Encephalopathies | American Journal of Human Genetics | 2017 | 337 |
| 19 | Severity of baseline magnetic resonance imaging–evident sacroiliitis and HLA–B27 status in early inflammatory back pain predict radiographically evident ankylosing spondylitis at eight years | Arthritis and Rheumatism | 2008 | 323 |
| 20 | The concept of a “synovio‐entheseal complex” and its implications for understanding joint inflammation and damage in psoriatic arthritis and beyond | Arthritis and Rheumatism | 2007 | 317 |
| 21 | DICER1 syndrome: clarifying the diagnosis, clinical features and management implications of a pleiotropic tumour predisposition syndrome | Journal of Medical Genetics | 2011 | 312 |
| 22 | Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer | Nature Genetics | 2017 | 289 |
| 23 | Efficacy of biological disease-modifying antirheumatic drugs: a systematic literature review informing the 2013 update of the EULAR recommendations for the management of rheumatoid arthritis | Annals of the Rheumatic Diseases | 2014 | 270 |
| 24 | Cancer Risks Associated With Germline PALB2 Pathogenic Variants: An International Study of 524 Families | Journal of Clinical Oncology | 2020 | 270 |
| 25 | TRPC channel activation by extracellular thioredoxin | Nature | 2008 | 260 |
| 26 | Scoring ultrasound synovitis in rheumatoid arthritis: a EULAR-OMERACT ultrasound taskforce — Part 1: definition and development of a standardised, consensus-based scoring system | RMD Open | 2017 | 250 |
| 27 | Tapering biologic and conventional DMARD therapy in rheumatoid arthritis: current evidence and future directions | Annals of the Rheumatic Diseases | 2016 | 232 |
| 28 | Development of psoriasis after B cell depletion with rituximab | Arthritis and Rheumatism | 2007 | 231 |
| 29 | British Association of Dermatologists guidelines for biologic therapy for psoriasis 2017 | British Journal of Dermatology | 2017 | 226 |
| 30 | Mutational spectrum in a worldwide study of 29,700 families withBRCA1orBRCA2mutations | Human Mutation | 2018 | 224 |
| 31 | The relationship between the extensor tendon enthesis and the nail in distal interphalangeal joint disease in psoriatic arthritis--a high-resolution MRI and histological study | Rheumatology | 2006 | 223 |
| 32 | Mosaic PPM1D mutations are associated with predisposition to breast and ovarian cancer | Nature | 2013 | 218 |
| 33 | A phase III randomised, double-blind, parallel-group study comparing SB4 with etanercept reference product in patients with active rheumatoid arthritis despite methotrexate therapy | Annals of the Rheumatic Diseases | 2017 | 201 |
| 34 | Consensus statement on the use of rituximab in patients with rheumatoid arthritis | Annals of the Rheumatic Diseases | 2006 | 194 |
| 35 | Randomized Controlled Trial of Rituximab and Cost‐Effectiveness Analysis in Treating Fatigue and Oral Dryness in Primary Sjögren's Syndrome | Arthritis and Rheumatology | 2017 | 194 |
| 36 | The 2017 EULAR standardised procedures for ultrasound imaging in rheumatology | Annals of the Rheumatic Diseases | 2017 | 191 |
| 37 | Risk factors for congenital anomaly in a multiethnic birth cohort: an analysis of the Born in Bradford study | Lancet, The | 2013 | 190 |
| 38 | Should imaging be a component of rheumatoid arthritis remission criteria? A comparison between traditional and modified composite remission scores and imaging assessments | Annals of the Rheumatic Diseases | 2011 | 185 |
| 39 | A diagnostic algorithm for persistence of very early inflammatory arthritis: the utility of power Doppler ultrasound when added to conventional assessment tools | Annals of the Rheumatic Diseases | 2010 | 177 |
| 40 | Synovial tissue research: a state-of-the-art review | Nature Reviews Rheumatology | 2017 | 175 |
| 41 | Native joint-resident mesenchymal stem cells for cartilage repair in osteoarthritis | Nature Reviews Rheumatology | 2017 | 173 |
| 42 | Consensus-based recommendations for the use of biosimilars to treat rheumatological diseases | Annals of the Rheumatic Diseases | 2018 | 173 |
| 43 | Patients with RA in remission on TNF blockers: when and in whom can TNF blocker therapy be stopped? | Annals of the Rheumatic Diseases | 2010 | 169 |
| 44 | Predicting the development of clinical arthritis in anti-CCP positive individuals with non-specific musculoskeletal symptoms: a prospective observational cohort study | Annals of the Rheumatic Diseases | 2015 | 169 |
| 45 | Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response to anti-TNF treatment | Annals of the Rheumatic Diseases | 2014 | 166 |
| 46 | Comprehensive Study of the Clinical Phenotype of GermlineBAP1Variant-Carrying Families Worldwide | Journal of the National Cancer Institute | 2018 | 164 |
| 47 | Glossary of terms for musculoskeletal radiology | Skeletal Radiology | 2020 | 163 |
| 48 | Development of a health index in patients with ankylosing spondylitis (ASAS HI): final result of a global initiative based on the ICF guided by ASAS | Annals of the Rheumatic Diseases | 2015 | 161 |
| 49 | A high-resolution magnetic resonance imaging study of distal interphalangeal joint arthropathy in psoriatic arthritis and osteoarthritis: Are they the same? | Arthritis and Rheumatism | 2006 | 160 |
| 50 | Tendon and ligament imaging | British Journal of Radiology | 2012 | 160 |
