| # | Title | Journal | Year | Citations |
|---|
| 1 | Intensive versus Conventional Glucose Control in Critically Ill Patients | New England Journal of Medicine | 2009 | 6,065 |
| 2 | Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries | JAMA - Journal of the American Medical Association | 2016 | 3,568 |
| 3 | Validity of the Eating Disorder Examination Questionnaire (EDE-Q) in screening for eating disorders in community samples | Behaviour Research and Therapy | 2004 | 881 |
| 4 | Increase in patient mortality at 10 days associated with emergency department overcrowding | Medical Journal of Australia | 2006 | 666 |
| 5 | Aberrant Mucin Assembly in Mice Causes Endoplasmic Reticulum Stress and Spontaneous Inflammation Resembling Ulcerative Colitis | PLoS Medicine | 2008 | 602 |
| 6 | Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus | Arthritis and Rheumatism | 2010 | 593 |
| 7 | Diagnosis and treatment of acute appendicitis: 2020 update of the WSES Jerusalem guidelines | World Journal of Emergency Surgery | 2020 | 533 |
| 8 | IFN-gamma plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis. | Journal of Immunology | 1996 | 511 |
| 9 | Gestational diabetes mellitus ‐ management guidelines: The Australasian Diabetes in Pregnancy Society | Medical Journal of Australia | 1998 | 506 |
| 10 | The Scourge of Antibiotic Resistance: The Important Role of the Environment | Clinical Infectious Diseases | 2013 | 487 |
| 11 | IFN-gamma plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis | Journal of Immunology | 1996 | 480 |
| 12 | Past exposure to sun, skin phenotype, and risk of multiple sclerosis: case-control study | BMJ: British Medical Journal | 2003 | 457 |
| 13 | Noninvasive Ventilation of Patients with Acute Respiratory Distress Syndrome. Insights from the LUNG SAFE Study | American Journal of Respiratory and Critical Care Medicine | 2017 | 456 |
| 14 | Expert consensus and recommendations on safety criteria for active mobilization of mechanically ventilated critically ill adults | Critical Care | 2014 | 391 |
| 15 | Stereotactic ablative radiotherapy versus standard radiotherapy in stage 1 non-small-cell lung cancer (TROG 09.02 CHISEL): a phase 3, open-label, randomised controlled trial | Lancet Oncology, The | 2019 | 386 |
| 16 | Neonatal Acute Kidney Injury | Pediatrics | 2015 | 384 |
| 17 | Human Health Consequences of Use of Antimicrobial Agents in Aquaculture | Clinical Infectious Diseases | 2009 | 382 |
| 18 | NAFLD in Asia—as common and important as in the West | Nature Reviews Gastroenterology and Hepatology | 2013 | 377 |
| 19 | Pesticide poisoning in the developing world—a minimum pesticides list | Lancet, The | 2002 | 375 |
| 20 | Sonography in the diagnosis of carpal tunnel syndrome. | American Journal of Roentgenology | 1999 | 368 |
| 21 | Fatty Acid Signaling in the -Cell and Insulin Secretion | Diabetes | 2006 | 359 |
| 22 | Asia–Pacific Working Party on Non‐alcoholic Fatty Liver Disease guidelines 2017—Part 1: Definition, risk factors and assessment | Journal of Gastroenterology and Hepatology (Australia) | 2018 | 358 |
| 23 | Two-Year Combination Antibiotic Therapy With Clarithromycin, Rifabutin, and Clofazimine for Crohn’s Disease | Gastroenterology | 2007 | 339 |
| 24 | NASH is an Infl ammatory Disorder: Pathogenic, Prognostic and Therapeutic Implications | Gut and Liver | 2012 | 334 |
| 25 | Fatal toxicity of serotoninergic and other antidepressant drugs: analysis of United Kingdom mortality data | BMJ: British Medical Journal | 2002 | 329 |
| 26 | World Health Organization Ranking of Antimicrobials According to Their Importance in Human Medicine: A Critical Step for Developing Risk Management Strategies for the Use of Antimicrobials in Food Production Animals | Clinical Infectious Diseases | 2009 | 306 |
| 27 | “Platinum resistant” ovarian cancer: What is it, who to treat and how to measure benefit? | Gynecologic Oncology | 2014 | 305 |
| 28 | Parkinson's disease, pesticides, and glutathione transferase polymorphisms | Lancet, The | 1998 | 303 |
| 29 | Resistance in bacteria of the food chain: epidemiology and control strategies | Expert Review of Anti-Infective Therapy | 2008 | 302 |
| 30 | Streptokinase for Acute Ischemic Stroke With Relationship to Time of Administration | JAMA - Journal of the American Medical Association | 1996 | 290 |
| 31 | Effect of Dexmedetomidine Added to Standard Care on Ventilator-Free Time in Patients With Agitated Delirium | JAMA - Journal of the American Medical Association | 2016 | 289 |
| 32 | WSES Jerusalem guidelines for diagnosis and treatment of acute appendicitis | World Journal of Emergency Surgery | 2016 | 288 |
| 33 | Hepatic Free Cholesterol Accumulates in Obese, Diabetic Mice and Causes Nonalcoholic Steatohepatitis | Gastroenterology | 2011 | 279 |
| 34 | Impact of endometriosis on women’s lives: a qualitative study | BMC Women's Health | 2014 | 269 |
| 35 | Bologna guidelines for diagnosis and management of adhesive small bowel obstruction (ASBO): 2017 update of the evidence-based guidelines from the world society of emergency surgery ASBO working group | World Journal of Emergency Surgery | 2018 | 265 |
| 36 | Society's failure to protect a precious resource: antibiotics | Lancet, The | 2011 | 259 |
| 37 | Non-beneficial treatments in hospital at the end of life: a systematic review on extent of the problem | International Journal for Quality in Health Care | 2016 | 253 |
| 38 | Characteristics of left ventricular diastolic dysfunction in the community: an echocardiographic survey | Heart | 2006 | 247 |
| 39 | Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study | Intensive Care Medicine | 2016 | 247 |
| 40 | The Aging Liver | Clinical Pharmacokinetics | 1998 | 245 |
| 41 | 2019 HRS/EHRA/APHRS/LAHRS expert consensus statement on catheter ablation of ventricular arrhythmias | Europace | 2019 | 245 |
| 42 | 2016 WSES guidelines on acute calculous cholecystitis | World Journal of Emergency Surgery | 2016 | 244 |
| 43 | Hartnup disorder is caused by mutations in the gene encoding the neutral amino acid transporter SLC6A19 | Nature Genetics | 2004 | 241 |
| 44 | Left Atrial Reverse Remodeling | JACC: Cardiovascular Imaging | 2017 | 240 |
| 45 | Serial circulating tumour DNA analysis during multimodality treatment of locally advanced rectal cancer: a prospective biomarker study | Gut | 2019 | 234 |
| 46 | Immune evasion via PD-1/PD-L1 on NK cells and monocyte/macrophages is more prominent in Hodgkin lymphoma than DLBCL | Blood | 2018 | 231 |
| 47 | World Health Organization Ranking of Antimicrobials According to Their Importance in Human Medicine: A Critical Step for Developing Risk Management Strategies to Control Antimicrobial Resistance From Food Animal Production | Clinical Infectious Diseases | 2016 | 230 |
| 48 | Molecular Cloning of Mouse Amino Acid Transport System B0, a Neutral Amino Acid Transporter Related to Hartnup Disorder | Journal of Biological Chemistry | 2004 | 222 |
| 49 | What are the risk factors and settings for non-alcoholic fatty liver disease in Asia?Pacific? | Journal of Gastroenterology and Hepatology (Australia) | 2007 | 220 |
| 50 | Cardiac troponin may be released by ischemia alone, without necrosis | Clinica Chimica Acta | 2010 | 218 |
