| # | Title | Journal | Year | Citations |
|---|
| 1 | Atezolizumab versus docetaxel for patients with previously treated non-small-cell lung cancer (POPLAR): a multicentre, open-label, phase 2 randomised controlled trial | Lancet, The | 2016 | 2,390 |
| 2 | TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis | Science | 2008 | 2,268 |
| 3 | Comparison of endovascular aneurysm repair with open repair in patients with abdominal aortic aneurysm (EVAR trial 1), 30-day operative mortality results: randomised controlled trial | Lancet, The | 2004 | 1,810 |
| 4 | Ramucirumab plus docetaxel versus placebo plus docetaxel for second-line treatment of stage IV non-small-cell lung cancer after disease progression on platinum-based therapy (REVEL): a multicentre, double-blind, randomised phase 3 trial | Lancet, The | 2014 | 1,068 |
| 5 | Consensus Statement on the classification of tremors. from the task force on tremor of the International Parkinson and Movement Disorder Society | Movement Disorders | 2018 | 918 |
| 6 | CONTROLLED TRIAL OF PREDNISOLONE IN ACUTE POLYNEUROPATHY | Lancet, The | 1978 | 865 |
| 7 | Epidemiology of sepsis and infection in ICU patients from an international multicentre cohort study | Intensive Care Medicine | 2002 | 835 |
| 8 | Vestibular migraine: Diagnostic criteria | Journal of Vestibular Research: Equilibrium and Orientation | 2012 | 787 |
| 9 | Triple-negative breast cancer: therapeutic options | Lancet Oncology, The | 2007 | 769 |
| 10 | Experimental validation of novel and conventional approaches to quantitative real-time PCR data analysis | Nucleic Acids Research | 2003 | 754 |
| 11 | Temozolomide: a review of its discovery, chemical properties, pre-clinical development and clinical trials | Cancer Treatment Reviews | 1997 | 717 |
| 12 | Shear-wave Elastography Improves the Specificity of Breast US: The BE1 Multinational Study of 939 Masses | Radiology | 2012 | 714 |
| 13 | Maintaining internal representations: the role of the human superior parietal lobe | Nature Neuroscience | 1998 | 670 |
| 14 | Reduced dendritic spine density on cerebral cortical pyramidal neurons in schizophrenia | Journal of Neurology, Neurosurgery and Psychiatry | 1998 | 644 |
| 15 | Mesenchymal precursor cells in the blood of normal individuals | Arthritis Research and Therapy | 2000 | 625 |
| 16 | The peripheral benzodiazepine binding site in the brain in multiple sclerosis | Brain | 2000 | 605 |
| 17 | Silver in Health Care: Antimicrobial Effects and Safety in Use | | 2006 | 575 |
| 18 | Cost-effectiveness analysis of micafungin versus caspofungin for treatment of systemic Candida infections in the UK | Current Medical Research and Opinion | 2009 | 570 |
| 19 | Characterization of an ocular photopigment capable of driving pupillary constriction in mice | Nature Neuroscience | 2001 | 546 |
| 20 | White matter damage and cognitive impairment after traumatic brain injury | Brain | 2011 | 541 |
| 21 | Zinc in wound healing: Theoretical, experimental, and clinical aspects | Wound Repair and Regeneration | 2007 | 516 |
| 22 | Paradox lost? Exploring the role of alpha oscillations during externally vs. internally directed attention and the implications for idling and inhibition hypotheses | International Journal of Psychophysiology | 2003 | 501 |
| 23 | Current and future developments in the use of temozolomide for the treatment of brain tumours | Lancet Oncology, The | 2001 | 493 |
| 24 | Determinant spreading and the dynamics of the autoimmune T-cell repertoire | Trends in Immunology | 1993 | 474 |
| 25 | Non-spatially lateralized mechanisms in hemispatial neglect | Nature Reviews Neuroscience | 2003 | 471 |
| 26 | Parkinson's disease symptoms: The patient's perspective | Movement Disorders | 2010 | 464 |
| 27 | Distinct frontal systems for response inhibition, attentional capture, and error processing | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 464 |
| 28 | Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H | Nature Genetics | 2002 | 461 |
| 29 | Phase I trial of temozolomide (CCRG 81045: M&B 39831: NSC 362856) | British Journal of Cancer | 1992 | 435 |
| 30 | Glycine receptor antibodies in PERM and related syndromes: characteristics, clinical features and outcomes | Brain | 2014 | 430 |
| 31 | Regional Brain Activity in Chronic Schizophrenic Patients during the Performance of a Verbal Fluency Task | British Journal of Psychiatry | 1995 | 417 |
| 32 | Default mode network functional and structural connectivity after traumatic brain injury | Brain | 2011 | 398 |
| 33 | The Symptomatic Carotid Plaque | Stroke | 2000 | 396 |
| 34 | Association of Prior Antibiotic Treatment With Survival and Response to Immune Checkpoint Inhibitor Therapy in Patients With Cancer | JAMA Oncology | 2019 | 396 |
| 35 | Reductions in all-cause, cancer, and coronary mortality in statin-treated patients with heterozygous familial hypercholesterolaemia: a prospective registry study | European Heart Journal | 2008 | 391 |
| 36 | Visualising microglial activation in vivo | Glia | 2002 | 383 |
| 37 | The effect of training distinct neurofeedback protocols on aspects of cognitive performance | International Journal of Psychophysiology | 2003 | 381 |
| 38 | Neuroprotective properties of the natural phenolic antioxidants curcumin and naringenin but not quercetin and fisetin in a 6-OHDA model of Parkinson's disease | Free Radical Research | 2005 | 380 |
| 39 | HISTOPATHOLOGY IN THE PREDICTION OF RELAPSE OF PATIENTS WITH STAGE I TESTICULAR TERATOMA TREATED BY ORCHIDECTOMY ALONE | Lancet, The | 1987 | 379 |
| 40 | Regulation of cytokines, cytokine inhibitors, and acute-phase proteins following anti-TNF-alpha therapy in rheumatoid arthritis | Journal of Immunology | 1999 | 377 |
| 41 | Regulation of Cytokines, Cytokine Inhibitors, and Acute-Phase Proteins Following Anti-TNF-α Therapy in Rheumatoid Arthritis | Journal of Immunology | 1999 | 368 |
| 42 | European Association of Urology Guidelines on Sexual and Reproductive Health—2021 Update: Male Sexual Dysfunction | European Urology | 2021 | 360 |
| 43 | Malnutrition and ageing | Postgraduate Medical Journal | 2006 | 358 |
| 44 | Defining response of ovarian carcinoma to initial chemotherapy according to serum CA 125. | Journal of Clinical Oncology | 1996 | 353 |
| 45 | Survival of Functionally Anuric Patients on Automated Peritoneal Dialysis: The European APD Outcome Study | Journal of the American Society of Nephrology: JASN | 2003 | 353 |
| 46 | Phase III Study of Gefitinib Compared With Intravenous Methotrexate for Recurrent Squamous Cell Carcinoma of the Head and Neck | Journal of Clinical Oncology | 2009 | 353 |
| 47 | The anterolateral ligament | Bone and Joint Journal | 2014 | 348 |
| 48 | The role of the pre-supplementary motor area in the control of action | NeuroImage | 2007 | 346 |
| 49 | Bowel dysfunction in spinal-cord-injury patients | Lancet, The | 1996 | 345 |
| 50 | Abnormal temporal dynamics of visual attention in spatial neglect patients | Nature | 1997 | 345 |
