| # | Title | Journal | Year | Citations |
|---|
| 1 | Prolonged Survival in Stage III Melanoma with Ipilimumab Adjuvant Therapy | New England Journal of Medicine | 2016 | 1,140 |
| 2 | The clinical symptoms of Parkinson's disease | Journal of Neurochemistry | 2016 | 830 |
| 3 | Confidential inquiry into quality of care before admission to intensive care | BMJ: British Medical Journal | 1998 | 810 |
| 4 | A phase III randomized comparison of lapatinib plus capecitabine versus capecitabine alone in women with advanced breast cancer that has progressed on trastuzumab: updated efficacy and biomarker analyses | Breast Cancer Research and Treatment | 2008 | 732 |
| 5 | Randomized controlled trial to investigate influence of the fluid challenge on duration of hospital stay and perioperative morbidity in patients with hip fractures † †These findings were presented in part at the 13th Annual Meeting of the European Society of Intensive Care Medicine, Rome 2000. | British Journal of Anaesthesia | 2002 | 405 |
| 6 | Zoledronic acid (zoledronate) for postmenopausal women with early breast cancer receiving adjuvant letrozole (ZO-FAST study): final 60-month results | Annals of Oncology | 2013 | 284 |
| 7 | Efficacy of zoledronic acid in postmenopausal women with early breast cancer receiving adjuvant letrozole: 36-month results of the ZO-FAST Study | Annals of Oncology | 2010 | 255 |
| 8 | Effective inhibition of aromatase inhibitor‐associated bone loss by zoledronic acid in postmenopausal women with early breast cancer receiving adjuvant letrozole | Cancer | 2008 | 209 |
| 9 | Expression of the Peptide Antibiotics Human β Defensin-1 and Human β Defensin-2 in Normal Human Skin | Journal of Investigative Dermatology | 2001 | 194 |
| 10 | The management of pain in the burns unit | Burns | 2009 | 189 |
| 11 | Extended schedule, escalated dose temozolomide versus dacarbazine in stage IV melanoma: Final results of a randomised phase III study (EORTC 18032) | European Journal of Cancer | 2011 | 189 |
| 12 | A Fenestrated Covered Suprarenal Aortic Stent | European Journal of Vascular and Endovascular Surgery | 1999 | 184 |
| 13 | The Evolution of Perforator Flap Breast Reconstruction: Twenty Years after the First DIEP Flap | Journal of Reconstructive Microsurgery | 2014 | 176 |
| 14 | Angioleiomyoma: a clinical, pathological and radiological review | International Journal of Clinical Practice | 2004 | 154 |
| 15 | Human β Defensin-1 and -2 Expression in Human Pilosebaceous Units: Upregulation in Acne Vulgaris Lesions | Journal of Investigative Dermatology | 2001 | 144 |
| 16 | Zoledronic acid significantly improves pain scores and quality of life in breast cancer patients with bone metastases: a randomised, crossover study of community vs hospital bisphosphonate administration | British Journal of Cancer | 2005 | 144 |
| 17 | Palate Re-Repair Revisited | Cleft Palate-Craniofacial Journal | 2002 | 139 |
| 18 | A multicentre, parallel-group comparison of calcipotriol ointment and short-contact dithranol therapy in chronic plaque psoriasis | British Journal of Dermatology | 1992 | 138 |
| 19 | The Aetiology of Acute Rupture of Flexor Tendon Repairs in Zones 1 and 2 of the Fingers During Early Mobilization | Journal of Hand Surgery | 1999 | 135 |
| 20 | Treatment of HER2-positive metastatic breast cancer with lapatinib and capecitabine in the lapatinib expanded access programme, including efficacy in brain metastases – the UK experience | British Journal of Cancer | 2010 | 131 |
| 21 | Primary Flexor Tendon Repair in Zone 1 | Journal of Hand Surgery | 2000 | 129 |
| 22 | Replacement of routine liver biopsy by procollagen III aminopeptide for monitoring patients with psoriasis receiving long-term methotrexate: a multicentre audit and health economic analysis | British Journal of Dermatology | 2005 | 124 |
| 23 | Primary Flexor Tendon Repair – Operative Repair, Pulley Management and Rehabilitation | Journal of Hand Surgery | 2002 | 122 |
| 24 | ORTHOPAEDIC BONE DRILLS – CAN THEY BE IMPROVED? | Journal of Bone and Joint Surgery: British Volume | 1996 | 120 |
| 25 | Smoke inhalation injury | BJA Education | 2015 | 114 |
| 26 | Repair and Reconstruction of Thumb and Finger Tip Injuries | Clinics in Plastic Surgery | 2014 | 112 |
| 27 | Clonidine prolongs the effect of ropivacaine for axillary brachial plexus blockade | Canadian Journal of Anaesthesia | 2000 | 105 |
| 28 | Venous augmentation of the free TRAM flap | Journal of Plastic, Reconstructive and Aesthetic Surgery | 2001 | 104 |
| 29 | Hyponatraemic states following 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') ingestion | QJM - Monthly Journal of the Association of Physicians | 2002 | 104 |
| 30 | “Venting” or Partial Lateral Release of the A2 and A4 Pulleys after Repair of Zone 2 Flexor Tendon Injuries | Journal of Hand Surgery | 1998 | 102 |
| 31 | Palate Re-Repair Revisited | Cleft Palate-Craniofacial Journal | 2002 | 102 |
| 32 | Submucous Cleft Palate: A Grading System and Review of 40 Consecutive Submucous Cleft Palate Repairs | Cleft Palate-Craniofacial Journal | 2004 | 101 |
| 33 | The prognostic value of end tidal carbon dioxide during cardiac arrest: A systematic review | Resuscitation | 2013 | 100 |
| 34 | Adjuvant bevacizumab in patients with melanoma at high risk of recurrence (AVAST-M): preplanned interim results from a multicentre, open-label, randomised controlled phase 3 study | Lancet Oncology, The | 2014 | 96 |
| 35 | Stat1 and CD74 overexpression is co-dependent and linked to increased invasion and lymph node metastasis in triple-negative breast cancer | Journal of Proteomics | 2012 | 92 |
| 36 | Population-based cohort study of outcomes following cholecystectomy for benign gallbladder diseases | British Journal of Surgery | 2016 | 84 |
| 37 | Comparative effects of calcipotriol solution (50 μg/ml) and betamethasone 17-valerate solution (1 mg/ml) in the treatment of scalp psoriasis | British Journal of Dermatology | 1994 | 81 |
| 38 | The Acute Care Undergraduate TEaching (ACUTE) Initiative: consensus development of core competencies in acute care for undergraduates in the United Kingdom | Intensive Care Medicine | 2005 | 81 |
| 39 | The transverse myocutaneous gracilis flap: technical refinements | Journal of Plastic, Reconstructive and Aesthetic Surgery | 2010 | 80 |
| 40 | Periorbital Fat Atrophy — An Unfamiliar Side Effect of Prostaglandin Analogues | Orbit | 2010 | 80 |
| 41 | Cardiovascular co-morbidity in chronic kidney disease: Current knowledge and future research needs | World Journal of Nephrology | 2014 | 79 |
| 42 | Breast implant associated anaplastic large cell lymphoma: The UK experience. Recommendations on its management and implications for informed consent | European Journal of Surgical Oncology | 2017 | 79 |
| 43 | Challenges and new horizons in the management of advanced basal cell carcinoma: a UK perspective | British Journal of Cancer | 2014 | 77 |
| 44 | The need to manage the risk of thromboembolism in COVID-19 patients | Journal of Vascular Surgery | 2020 | 77 |
| 45 | Indocyanine green-based fluorescent angiography in breast reconstruction | Gland Surgery | 2016 | 76 |
| 46 | Treatment of End-Neuromas, Neuromas-in-Continuity and Scarred Nerves of the Digits by Proximal Relocation | Journal of Hand Surgery | 2004 | 75 |
| 47 | A Systemic Review of Adult Mesenchymal Stem Cell Sources and their Multilineage Differentiation Potential Relevant to Musculoskeletal Tissue Repair and Regeneration | Current Stem Cell Research and Therapy | 2017 | 75 |
| 48 | Prostanoid receptor EP1 and Cox-2 in injured human nerves and a rat model of nerve injury: a time-course study | BMC Neurology | 2006 | 74 |
| 49 | Pruritus in Burns: Review Article | Journal of Burn Care and Research | 2009 | 74 |
| 50 | Epidemiology, diagnosis, and management of esophageal perforations: systematic review | Ecological Management and Restoration | 2017 | 74 |
