| # | Title | Journal | Year | Citations |
|---|
| 1 | Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials | Lancet, The | 2016 | 5,331 |
| 2 | DNA methylation-based classification of central nervous system tumours | Nature | 2018 | 1,872 |
| 3 | Ibrutinib versus Ofatumumab in Previously Treated Chronic Lymphoid Leukemia | New England Journal of Medicine | 2014 | 1,427 |
| 4 | Superiority of Ambulatory Over Clinic Blood Pressure Measurement in Predicting Mortality | Hypertension | 2005 | 1,098 |
| 5 | Prognostic Value of Ambulatory Blood-Pressure Recordings in Patients with Treated Hypertension | New England Journal of Medicine | 2003 | 997 |
| 6 | A Mutation in the TRPC6 Cation Channel Causes Familial Focal Segmental Glomerulosclerosis | Science | 2005 | 967 |
| 7 | A BLINDED, RANDOMIZED CLINICAL TRIAL OF MYCOPHENOLATE MOFETIL FOR THE PREVENTION OF ACUTE REJECTION IN CADAVERIC RENAL TRANSPLANTATION1 | Transplantation | 1996 | 933 |
| 8 | Blood pressure measuring devices: recommendations of the European Society of Hypertension | BMJ: British Medical Journal | 2001 | 731 |
| 9 | Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma | Cancer Cell | 2017 | 716 |
| 10 | Natural selection on EPAS1 ( HIF2α ) associated with low hemoglobin concentration in Tibetan highlanders | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 708 |
| 11 | A Prospective, Randomized Clinical Trial of Hemodynamic Support With Impella 2.5 Versus Intra-Aortic Balloon Pump in Patients Undergoing High-Risk Percutaneous Coronary Intervention | Circulation | 2012 | 680 |
| 12 | Skin test concentrations for systemically administered drugs – an ENDA/EAACI Drug Allergy Interest Group position paper | Allergy: European Journal of Allergy and Clinical Immunology | 2013 | 656 |
| 13 | Working Group on Blood Pressure Monitoring of the European Society of Hypertension International Protocol for validation of blood pressure measuring devices in adults | Blood Pressure Monitoring | 2002 | 641 |
| 14 | Practice guidelines of the European Society of Hypertension for clinic, ambulatory and self blood pressure measurement | Journal of Hypertension | 2005 | 628 |
| 15 | The British Hypertension Society protocol for the evaluation of automated and semi-automated blood pressure measuring devices with special reference to ambulatory systems | Journal of Hypertension | 1990 | 598 |
| 16 | Angiogenic and cell survival functions of Vascular Endothelial Growth Factor (VEGF) | Journal of Cellular and Molecular Medicine | 2005 | 598 |
| 17 | Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: ASCO Guideline Update | Journal of Clinical Oncology | 2021 | 580 |
| 18 | Cognitive impairment in amyotrophic lateral sclerosis | Lancet Neurology, The | 2007 | 566 |
| 19 | The syndrome of cognitive impairment in amyotrophic lateral sclerosis: a population-based study | Journal of Neurology, Neurosurgery and Psychiatry | 2012 | 557 |
| 20 | STS-ACC TVT Registry of Transcatheter Aortic Valve Replacement | Journal of the American College of Cardiology | 2020 | 511 |
| 21 | Predictors of infection in rheumatoid arthritis | Arthritis and Rheumatism | 2002 | 507 |
| 22 | The Pharmacology, Metabolism, Analysis, and Applications of Coumarin and Coumarin-Related Compounds | Drug Metabolism Reviews | 1990 | 497 |
| 23 | Cognitive and clinical characteristics of patients with amyotrophic lateral sclerosis carrying a C9orf72 repeat expansion: a population-based cohort study | Lancet Neurology, The | 2012 | 493 |
| 24 | Characterization of the Inflammatory Response to Severe COVID-19 Illness | American Journal of Respiratory and Critical Care Medicine | 2020 | 487 |
| 25 | Tumour hypoxia, chemotherapeutic resistance and hypoxia-related therapies | Cancer Treatment Reviews | 2003 | 484 |
| 26 | The consequences of refractory epilepsy and its treatment | Epilepsy and Behavior | 2014 | 482 |
| 27 | Hypertensive emergencies | Lancet, The | 2000 | 479 |
| 28 | Effect of tamoxifen and radiotherapy in women with locally excised ductal carcinoma in situ: long-term results from the UK/ANZ DCIS trial | Lancet Oncology, The | 2011 | 476 |
| 29 | Iron Status and Restless Legs Syndrome in the Elderly | Age and Ageing | 1994 | 470 |
| 30 | Structure-based design of aliskiren, a novel orally effective renin inhibitor | Biochemical and Biophysical Research Communications | 2003 | 470 |
| 31 | Real-time differentiation of adenomatous and hyperplastic diminutive colorectal polyps during analysis of unaltered videos of standard colonoscopy using a deep learning model | Gut | 2019 | 462 |
| 32 | Surgical Versus Nonoperative Treatment for Lumbar Spinal Stenosis Four-Year Results of the Spine Patient Outcomes Research Trial | Spine | 2010 | 454 |
| 33 | Controversies and priorities in amyotrophic lateral sclerosis | Lancet Neurology, The | 2013 | 454 |
| 34 | Guidelines for topical photodynamic therapy: report of a workshop of the British Photodermatology Group | British Journal of Dermatology | 2002 | 444 |
| 35 | Safety Recommendations for Evaluation and Surgery of the Head and Neck During the COVID-19 Pandemic | JAMA Otolaryngology - Head and Neck Surgery | 2020 | 430 |
| 36 | 2016 Annual Report of The Society of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy Registry | Journal of the American College of Cardiology | 2017 | 429 |
| 37 | A NovelStaphylococcus aureusBiofilm Phenotype Mediated by the Fibronectin-Binding Proteins, FnBPA and FnBPB | Journal of Bacteriology | 2008 | 425 |
| 38 | Survival in rheumatoid arthritis: A population-based analysis of trends over 40 years | Arthritis and Rheumatism | 2003 | 423 |
| 39 | Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects | Nature Medicine | 2012 | 423 |
| 40 | Intravenous augmentation treatment and lung density in severe α1 antitrypsin deficiency (RAPID): a randomised, double-blind, placebo-controlled trial | Lancet, The | 2015 | 408 |
| 41 | Randomized Trial of Percutaneous Tibial Nerve Stimulation Versus Sham Efficacy in the Treatment of Overactive Bladder Syndrome: Results From the SUmiT Trial | Journal of Urology | 2010 | 404 |
| 42 | Clinical Features of Amyotrophic Lateral Sclerosis According to the El Escorial and Airlie House Diagnostic Criteria | Archives of Neurology | 2000 | 403 |
| 43 | Effect of a multidisciplinary amyotrophic lateral sclerosis (ALS) clinic on ALS survival: a population based study, 1996-2000 | Journal of Neurology, Neurosurgery and Psychiatry | 2003 | 403 |
| 44 | The Prognostic Significance of Delirium in Older Hospital Patients | Journal of the American Geriatrics Society | 1997 | 402 |
| 45 | Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial | Lancet, The | 2020 | 400 |
| 46 | A population-based study of skin cancer incidence and prevalence in renal transplant recipients | British Journal of Dermatology | 2006 | 394 |
| 47 | Clinicopathological significance of psychotic experiences in non-psychotic young people: evidence from four population-based studies | British Journal of Psychiatry | 2012 | 389 |
| 48 | Reduction in Cardiovascular Events With Atorvastatin in 2,532 Patients With Type 2 Diabetes | Diabetes Care | 2005 | 377 |
| 49 | Use and interpretation of ambulatory blood pressure monitoring: recommendations of the British Hypertension Society | BMJ: British Medical Journal | 2000 | 366 |
| 50 | Accuracy of the SpaceLabs 90207 determined by the British Hypertension Society Protocol | Journal of Hypertension | 1991 | 354 |
