1.1K(top 1%)
papers
56.0K(top 0.1%)
citations
115(top 0.1%)
h-index
191(top 0.1%)
g-index
1.1K
all documents
58.2K
doc citations
4.0K
citing journals

Top Articles

#TitleJournalYearCitations
1Signalling through the lipid products of phosphoinositide-3-OH kinaseNature19971,290
2Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALSNature20131,249
3Cellular Defenses against Unfolded ProteinsNeuron2001948
4Mechanisms of smooth muscle contractionPhysiological Reviews1996659
5Regulation of protein kinase C ζ by PI 3-kinase and PDK-1Current Biology1998600
6Activation of Phosphoinositide 3-OH Kinase by the α6β4 Integrin Promotes Carcinoma InvasionCell1997588
7Single-column purification of free recombinant proteins using a self-cleavable affinity tag derived from a protein splicing elementGene1997579
8Boundary analysis in sedimentation transport experiments: A procedure for obtaining sedimentation coefficient distributions using the time derivative of the concentration profileAnalytical Biochemistry1992572
9The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative diseaseBrain Research2012572
10The Rat Grimace Scale: A Partially Automated Method for Quantifying Pain in the Laboratory Rat via Facial ExpressionsMolecular Pain2011521
11Mechanical compression drives cancer cells toward invasive phenotypeProceedings of the National Academy of Sciences of the United States of America2012507
12The Crystal Structure of Uncomplexed Actin in the ADP StateScience2001484
13Hsp70 Prevents Activation of Stress KinasesJournal of Biological Chemistry1997473
14AKT-Independent Signaling Downstream of Oncogenic PIK3CA Mutations in Human CancerCancer Cell2009472
15Akt/Protein Kinase B Is Regulated by Autophosphorylation at the Hypothetical PDK-2 SiteJournal of Biological Chemistry2000436
16Protein Splicing and Related Forms of Protein AutoprocessingAnnual Review of Biochemistry2000420
17Phosphoinositide 3-kinase and Akt are essential for Sonic Hedgehog signalingProceedings of the National Academy of Sciences of the United States of America2006418
18Evidence that Inositol Polyphosphate 4-Phosphatase Type II Is a Tumor Suppressor that Inhibits PI3K SignalingCancer Cell2009411
19Rotational diffusion studied by passage saturation transfer electron paramagnetic resonanceJournal of Chemical Physics1976410
20Akt Blocks Breast Cancer Cell Motility and Invasion through the Transcription Factor NFATMolecular Cell2005390
21Identification of the miR-106b ~ 25 MicroRNA Cluster as a Proto-Oncogenic PTEN -Targeting Intron That Cooperates with Its Host Gene MCM7 in TransformationScience Signaling2010390
22Thin Filament Proteins and Thin Filament-Linked Regulation of Vertebrate Muscle ContractioCritical Reviews in Biochemistry1984388
23Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulinNature2002388
24A yeast functional screen predicts new candidate ALS disease genesProceedings of the National Academy of Sciences of the United States of America2011365
25Regulation of conventional protein kinase C isozymes by phosphoinositide-dependent kinase 1 (PDK-1)Current Biology1998357
26Structural basis of protein phosphatase 1 regulationNature2004355
27Systemic Elevation of PTEN Induces a Tumor-Suppressive Metabolic StateCell2012339
28Structural Basis for Diversity of the EF-hand Calcium-binding ProteinsJournal of Molecular Biology2006334
29The motor protein myosin-I produces its working stroke in two stepsNature1999328
30Signaling through protein kinase CFrontiers in Bioscience - Landmark1998294
31Purification and Properties of the Components from TroponinJournal of Biological Chemistry1973293
32Proteasome Inhibitors Activate Stress Kinases and Induce Hsp72Journal of Biological Chemistry1998280
33Fast and slow dynamics of the cytoskeletonNature Materials2006279
34Three-dimensional structure of adenyl kinaseNature1974277
35Prion-like disorders: blurring the divide between transmissibility and infectivityJournal of Cell Science2010268
36The amino acid sequence of rabbit skeletal muscle troponin C: Gene replication and homology with calcium -binding proteins from carp and hake muscleFEBS Letters1973261
37The synthesis and cellular roles of phosphatidylinositol 4,5-bisphosphateCurrent Opinion in Cell Biology1998257
38Analysis of heterologous interacting systems by sedimentation velocity: curve fitting algorithms for estimation of sedimentation coefficients, equilibrium and kinetic constantsBiophysical Chemistry2004246
39Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosisHuman Molecular Genetics2012246
40Preparation of bispecific antibodies by chemical recombination of monoclonal immunoglobulin G1 fragmentsScience1985244
41Postulated role of calsequestrin in the regulation of calcium release from sarcoplasmic reticulumBiochemistry1989234
42Protein-Damaging Stresses Activate c-Jun N-Terminal Kinase via Inhibition of Its Dephosphorylation: a Novel Pathway Controlled by HSP72Molecular and Cellular Biology1999234
43Protein Splicing Involving the Saccharomyces cerevisiae VMA InteinJournal of Biological Chemistry1996233
44The content of troponin, tropomyosin, actin, and myosin in rabbit skeletal muscle myofibrilsArchives of Biochemistry and Biophysics1974229
45Actin-bound structures of Wiskott-Aldrich syndrome protein (WASP)-homology domain 2 and the implications for filament assemblyProceedings of the National Academy of Sciences of the United States of America2005228
46Rnd Proteins Function as RhoA Antagonists by Activating p190 RhoGAPCurrent Biology2003222
47Leptin Signaling Promotes the Growth of Mammary Tumors and Increases the Expression of Vascular Endothelial Growth Factor (VEGF) and Its Receptor Type Two (VEGF-R2)Journal of Biological Chemistry2006216
48Role of Hsp70 in regulation of stress-kinase JNK: implications in apoptosis and agingFEBS Letters1998215
49Phosphoinositides and signal transductionCellular and Molecular Life Sciences2002213
50Invited Review: Cross-bridge regulation by thin filament-associated proteinsJournal of Applied Physiology2001212