| Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases | Cell Research | 2008 | 3.5K |
| The diploid genome sequence of an Asian individual | Nature | 2008 | 744 |
| TreeFam: 2008 Update | Nucleic Acids Research | 2008 | 234 |
| On the nature of human housekeeping genes | Trends in Genetics | 2008 | 194 |
| Genome-wide assessment of worldwide chicken SNP genetic diversity indicates significant absence of rare alleles in commercial breeds | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 180 |
| Genetic susceptibility to heroin addiction: a candidate gene association study | Genes, Brain and Behavior | 2008 | 167 |
| CFH and LOC387715/ARMS2 genotypes and treatment with antioxidants and zinc for age-related macular degeneration | Ophthalmology | 2008 | 141 |
| ABCB1 (MDR1) genetic variants are associated with methadone doses required for effective treatment of heroin dependence | Human Molecular Genetics | 2008 | 133 |
| The binding of thioflavin T and its neutral analog BTA-1 to protofibrils of the Alzheimer's disease Abeta(16-22) peptide probed by molecular dynamics simulations | Journal of Molecular Biology | 2008 | 119 |
| Evolution and pathogenesis of Staphylococcus aureus: lessons learned from genotyping and comparative genomics | FEMS Microbiology Reviews | 2008 | 111 |
| How many human genes can be defined as housekeeping with current expression data? | BMC Genomics | 2008 | 106 |
| The silkworm (Bombyx mori) microRNAs and their expressions in multiple developmental stages | PLoS ONE | 2008 | 105 |
| MethyCancer: the database of human DNA methylation and cancer | Nucleic Acids Research | 2008 | 102 |
| Environmental adaptation: genomic analysis of the piezotolerant and psychrotolerant deep-sea iron reducing bacterium Shewanella piezotolerans WP3 | PLoS ONE | 2008 | 101 |
| The Well-of-the-Well system: an efficient approach to improve embryo development | Reproductive BioMedicine Online | 2008 | 93 |
| CpG island methylator phenotype associates with low-degree chromosomal abnormalities in colorectal cancer | Clinical Cancer Research | 2008 | 86 |
| A novel OxyR sensor and regulator of hydrogen peroxide stress with one cysteine residue in Deinococcus radiodurans | PLoS ONE | 2008 | 85 |
| Rhesus monkeys and humans share common susceptibility genes for age-related macular disease | Human Molecular Genetics | 2008 | 82 |
| Alleles in the HtrA serine peptidase 1 gene alter the risk of neovascular age-related macular degeneration | Ophthalmology | 2008 | 80 |
| Genotype patterns that contribute to increased risk for or protection from developing heroin addiction | Molecular Psychiatry | 2008 | 78 |
| A novel gene, encoding 6-hydroxy-3-succinoylpyridine hydroxylase, involved in nicotine degradation by Pseudomonas putida strain S16 | Applied and Environmental Microbiology | 2008 | 58 |
| Independent losses of function in a polyphenol oxidase in rice: differentiation in grain discoloration between subspecies and the role of positive selection under domestication | Plant Cell | 2008 | 58 |
| Proteomic profiling of rice embryos from a hybrid rice cultivar and its parental lines | Proteomics | 2008 | 47 |
| Comparative analysis of ESTs in response to drought stress in chickpea (C. arietinum L.) | Biochemical and Biophysical Research Communications | 2008 | 41 |
| Gene conversion in the rice genome | BMC Genomics | 2008 | 40 |
