| # | Title | Journal | Year | Citations |
|---|
| 1 | Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase | Cell Research | 2014 | 1,719 |
| 2 | Nuclear m 6 A Reader YTHDC1 Regulates mRNA Splicing | Molecular Cell | 2016 | 1,432 |
| 3 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 4 | KaKs_Calculator 2.0: A Toolkit Incorporating Gamma-Series Methods and Sliding Window Strategies | Genomics, Proteomics and Bioinformatics | 2010 | 1,301 |
| 5 | On the classification of long non-coding RNAs | RNA Biology | 2013 | 1,040 |
| 6 | KaKs_Calculator: Calculating Ka and Ks Through Model Selection and Model Averaging | Genomics, Proteomics and Bioinformatics | 2006 | 940 |
| 7 | FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesis | Cell Research | 2014 | 869 |
| 8 | Resequencing 50 accessions of cultivated and wild rice yields markers for identifying agronomically important genes | Nature Biotechnology | 2012 | 818 |
| 9 | Heightened Innate Immune Responses in the Respiratory Tract of COVID-19 Patients | Cell Host and Microbe | 2020 | 811 |
| 10 | The Genomes of Oryza sativa: A History of Duplications | PLoS Biology | 2005 | 808 |
| 11 | Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects | Nature Methods | 2014 | 716 |
| 12 | A Brief Review on the Mechanisms of miRNA Regulation | Genomics, Proteomics and Bioinformatics | 2009 | 711 |
| 13 | Natural selection on EPAS1 ( HIF2α ) associated with low hemoglobin concentration in Tibetan highlanders | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 708 |
| 14 | An Aboriginal Australian Genome Reveals Separate Human Dispersals into Asia | Science | 2011 | 675 |
| 15 | 5-methylcytosine promotes mRNA export — NSUN2 as the methyltransferase and ALYREF as an m5C reader | Cell Research | 2017 | 666 |
| 16 | The genomes of four tapeworm species reveal adaptations to parasitism | Nature | 2013 | 603 |
| 17 | The human urinary proteome contains more than 1500 proteins, including a large proportion of membrane proteins | Genome Biology | 2006 | 598 |
| 18 | Genome sequence and genetic diversity of the common carp, Cyprinus carpio | Nature Genetics | 2014 | 576 |
| 19 | GSA: Genome Sequence Archive * | Genomics, Proteomics and Bioinformatics | 2017 | 563 |
| 20 | PGAP: pan-genomes analysis pipeline | Bioinformatics | 2012 | 498 |
| 21 | m6A RNA Methylation Is Regulated by MicroRNAs and Promotes Reprogramming to Pluripotency | Cell Stem Cell | 2015 | 483 |
| 22 | TreeFam: a curated database of phylogenetic trees of animal gene families | Nucleic Acids Research | 2006 | 465 |
| 23 | Programming and Inheritance of Parental DNA Methylomes in Mammals | Cell | 2014 | 451 |
| 24 | Unguided Species Delimitation Using DNA Sequence Data from Multiple Loci | Molecular Biology and Evolution | 2014 | 449 |
| 25 | Sperm, but Not Oocyte, DNA Methylome Is Inherited by Zebrafish Early Embryos | Cell | 2013 | 428 |
| 26 | 3D Chromatin Structures of Mature Gametes and Structural Reprogramming during Mammalian Embryogenesis | Cell | 2017 | 415 |
| 27 | ParaAT: A parallel tool for constructing multiple protein-coding DNA alignments | Biochemical and Biophysical Research Communications | 2012 | 377 |
| 28 | Full‐length transcriptome sequences and splice variants obtained by a combination of sequencing platforms applied to different root tissues of Salvia miltiorrhiza and tanshinone biosynthesis | Plant Journal | 2015 | 337 |
| 29 | Activating mutations of STAT5B and STAT3 in lymphomas derived from γδ-T or NK cells | Nature Communications | 2015 | 334 |
| 30 | The rubber tree genome reveals new insights into rubber production and species adaptation | Nature Plants | 2016 | 324 |
| 31 | Mettl3-mediated m6A regulates spermatogonial differentiation and meiosis initiation | Cell Research | 2017 | 306 |
| 32 | Fungal diversity notes 1–110: taxonomic and phylogenetic contributions to fungal species | Fungal Diversity | 2015 | 304 |
| 33 | Metagenomic Analysis of Fever, Thrombocytopenia and Leukopenia Syndrome (FTLS) in Henan Province, China: Discovery of a New Bunyavirus | PLoS Pathogens | 2011 | 298 |
| 34 | TreeFam: 2008 Update | Nucleic Acids Research | 2007 | 294 |
| 35 | Global genome expression analysis of rice in response to drought and high-salinity stresses in shoot, flag leaf, and panicle | Plant Molecular Biology | 2007 | 275 |
| 36 | Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations | Nature Genetics | 2011 | 260 |
| 37 | The Complete Chloroplast Genome Sequence of Date Palm (Phoenix dactylifera L.) | PLoS ONE | 2010 | 255 |
| 38 | Identification of ten serum microRNAs from a genome‐wide serum microRNA expression profile as novel noninvasive biomarkers for nonsmall cell lung cancer diagnosis | International Journal of Cancer | 2012 | 251 |
| 39 | A novel m6A reader Prrc2a controls oligodendroglial specification and myelination | Cell Research | 2019 | 250 |
| 40 | On the nature of human housekeeping genes | Trends in Genetics | 2008 | 249 |
| 41 | MicroRNA Cluster 302–367 Enhances Somatic Cell Reprogramming by Accelerating a Mesenchymal-to-Epithelial Transition | Journal of Biological Chemistry | 2011 | 231 |
| 42 | Long Non-coding RNAs and Their Biological Roles in Plants | Genomics, Proteomics and Bioinformatics | 2015 | 231 |
| 43 | Cassava genome from a wild ancestor to cultivated varieties | Nature Communications | 2014 | 230 |
| 44 | Scleral hypoxia is a target for myopia control | Proceedings of the National Academy of Sciences of the United States of America | 2018 | 224 |
| 45 | Taxonomy of the order Mononegavirales: update 2019 | Archives of Virology | 2019 | 224 |
| 46 | METTL3-mediated m6A modification is required for cerebellar development | PLoS Biology | 2018 | 216 |
| 47 | A pyrosequencing-based metagenomic study of methane-producing microbial community in solid-state biogas reactor | Biotechnology for Biofuels | 2013 | 213 |
| 48 | Oral Microbiota Community Dynamics Associated With Oral Squamous Cell Carcinoma Staging | Frontiers in Microbiology | 2018 | 211 |
| 49 | Comparative transcriptome analysis of transporters, phytohormone and lipid metabolism pathways in response to arsenic stress in rice (Oryza sativa) | New Phytologist | 2012 | 193 |
| 50 | EWAS Atlas: a curated knowledgebase of epigenome-wide association studies | Nucleic Acids Research | 2019 | 193 |
